Zobrazeno 1 - 10
of 16
pro vyhledávání: '"C N, Habecker"'
Autor:
Brian T. Phillips, J.J. Lynch, David A. Claremon, Stella W. King, C. N. Habecker, John W. Butcher, Elliott Jason M, H. G. Selnick, John J. Baldwin, Buhrow Sa
Publikováno v:
Journal of Medicinal Chemistry. 35:3973-3976
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c774878b59977cdbbcfd6f0058a247
https://doi.org/10.1021/jm00099a028
https://doi.org/10.1021/jm00099a028
Autor:
G M, Smith, R S, Alexander, D W, Christianson, B M, McKeever, G S, Ponticello, J P, Springer, W C, Randall, J J, Baldwin, C N, Habecker
Publikováno v:
Protein science : a publication of the Protein Society. 3(1)
The 3-dimensional structure of human carbonic anhydrase II (HCAII; EC 4.2.1.1) complexed with 3 structurally related inhibitors, 1a, 1b, and 1c, has been determined by X-ray crystallographic methods. The 3 inhibitors (1a = C8H12N2O4S3) vary only in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c04f59e61e42db18c27e213a21e2f5bf
https://pubmed.ncbi.nlm.nih.gov/8142888
https://pubmed.ncbi.nlm.nih.gov/8142888
Autor:
Marcia E. Christy, Robert L. Smith, Anthony M. Smith, J. M. Sondey, K. M. Strohmaier, P. Gautheron, Samuel L. Graham, Stuart R. Michelson, P. A. Lyle, Gerald S. Ponticello, C. M. Robb, D. B. Best, J. M. Hoffman, M. F. Sugrue, Kenneth L. Shepard, Mark B. Freedman, P. S. Anderson, John J. Baldwin, C. N. Habecker, Harvey Schwam, Sandor L. Varga
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb14c5e88db3a417b1974766bb6325c7
https://doi.org/10.1002/chin.199017166
https://doi.org/10.1002/chin.199017166
Autor:
Adolph M. Pietruszkiewicz, William A. Bolhofer, C. N. Habecker, Henry I. Jacoby, M. L. Torchiana, Clement A. Stone
Publikováno v:
Journal of Medicinal Chemistry. 22:295-301
A series of N-substituted 2-mercaptoacetamidines was synthesized and evaluated for gastric antisecretory activity in dogs stimulated with gastrin tetrapeptide. The most potent analogues showed 80--95% inhibition of acid secretion after an oral dose o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab794c23208d884fdd9d6ae8ceb2069f
https://doi.org/10.1021/jm00189a015
https://doi.org/10.1021/jm00189a015
Autor:
M. L. Torchiana, William A. Bolhofer, C. N. Habecker, Jacob M. Hoffman, Adolph M. Pietruszkiewicz, Edward J. Cragoe
Publikováno v:
Journal of Medicinal Chemistry. 22:301-306
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fec34f0528f62d844e1fd104c0e55c
https://doi.org/10.1021/jm00189a016
https://doi.org/10.1021/jm00189a016
Autor:
W C, Lumma, P S, Anderson, J J, Baldwin, W A, Bolhofer, C N, Habecker, J M, Hirshfield, A M, Pietruszkiewicz, W C, Randall, M L, Torchiana, S F, Britcher, B V, Clineschmidt, G H, Denny, R, Hirschmann, M J, Hoffman, B T, Phillips, K B, Streeter
Publikováno v:
Journal of Medicinal Chemistry. 25:207-210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eada44763f65fb6833747fe15d1ca09
https://doi.org/10.1021/jm00345a002
https://doi.org/10.1021/jm00345a002
Autor:
C. N. Habecker, Samuel L. Graham, D. B. Best, John J. Baldwin, Marcia E. Christy, Mark B. Freedman, Kenneth L. Shepard, P. Gautheron, Jacob M. Hoffman, P. S. Anderson
Publikováno v:
Journal of Medicinal Chemistry. 32:2548-2554
Derivatives of benzo[b]thiophene-2-sulfonamide were prepared to investigate their potential utility as topically active inhibitors of ocular carbonic anhydrase. Such an agent would be useful in the treatment of glaucoma. Among the compounds described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672b0bec8893bfb409749f70db2b986b
https://doi.org/10.1021/jm00132a009
https://doi.org/10.1021/jm00132a009
Autor:
J. J. BALDWIN, M. E. CHRISTY, G. H. DENNY, C. N. HABECKER, M. B. FREEDMAN, P. A. LYLE, G. S. PONTICELLO, S. L. VARGA, D. M. GROSS, C. S. SWEET
Publikováno v:
Chemischer Informationsdienst. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03603b1ee207ed2c7a44adfaf90dcf06
https://doi.org/10.1002/chin.198644181
https://doi.org/10.1002/chin.198644181
Autor:
J J, Baldwin, M E, Christy, G H, Denny, C N, Habecker, M B, Freedman, P A, Lyle, G S, Ponticello, S L, Varga, D M, Gross, C S, Sweet
Publikováno v:
Journal of medicinal chemistry. 29(6)
An attempt to develop a highly cardioselective beta-adrenoceptor antagonist devoid of intrinsic sympathomimetic activity (ISA) focused on exploring structure-activity relationships around (S)-[p-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-hydroxypropo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17d871b3bfc35a73d98b7128ab388948
https://pubmed.ncbi.nlm.nih.gov/2872332
https://pubmed.ncbi.nlm.nih.gov/2872332
Autor:
Marcia E. Christy, D. M. Gross, P. A. Lyle, Mark B. Freedman, Charles S. Sweet, George H. Denny, C. N. Habecker, John J. Baldwin, Sandor L. Varga, Gerald S. Ponticello
Publikováno v:
Chemischer Informationsdienst. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::799124fa407bf50a8a8b0f438aceee18
https://doi.org/10.1002/chin.198348210
https://doi.org/10.1002/chin.198348210