Zobrazeno 1 - 10
of 152
pro vyhledávání: '"C N, Falany"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 6, Pp 1139-1148 (1997)
A mouse liver lambda Zap XR cDNA library was screened using the coding region of human bile acid CoA:amino acid N-acyltransferase (BAT) cDNA as a probe. Ten positive clones were isolated and purified, two of which apparently possessed complete open r
Externí odkaz:
https://doaj.org/article/1c448cbe44a5469098637474ea819230
Autor:
Mo, Jia‐Wen1 (AUTHOR), Kong, Peng‐Li1 (AUTHOR), Ding, Li1 (AUTHOR), Fan, Jun1 (AUTHOR), Ren, Jing1 (AUTHOR), Lu, Cheng‐Lin1,2 (AUTHOR), Guo, Fang1 (AUTHOR), Chen, Liang‐Yu1 (AUTHOR), Mo, Ran1 (AUTHOR), Zhong, Qiu‐Ling1 (AUTHOR), Wen, You‐Lu3 (AUTHOR), Gu, Ting‐Ting3 (AUTHOR), Wang, Qian‐Wen4 (AUTHOR), Li, Shu‐Ji1 (AUTHOR), Guo, Ting1 (AUTHOR), Gao, Tian‐Ming1 (AUTHOR), Cao, Xiong1,2,5 (AUTHOR) caoxiong@smu.edu.cn
Publikováno v:
Advanced Science. 11/6/2024, Vol. 11 Issue 41, p1-17. 17p.
Autor:
Vyas SK; Department of Medicinal Chemistry, Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Govt. of India, Sila Katamur (Halugurisuk), P.O.: Changsari, Dist: Kamrup, Pin, National Institute of Pharmaceutical Education and Research, Guwahati, (NIPER Guwahati), Guwahati, Assam, 781101, India., Das A; Department of Pharmacy, Birla Institute of Technology and Sciences Pilani (BITS-Pilani), Vidya Vihar Campus 41, Pilani, Rajasthan, 333031, India.; Current address: Department of Primary Intelligence, IQVIA, Sarjapur-Marathahalli Outer Ring Road Embassy Tech Square, Bangalore, 560103 Karnataka, India., Suryanarayana Murty U; Department of Medicinal Chemistry, Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Govt. of India, Sila Katamur (Halugurisuk), P.O.: Changsari, Dist: Kamrup, Pin, National Institute of Pharmaceutical Education and Research, Guwahati, (NIPER Guwahati), Guwahati, Assam, 781101, India., Dixit VA; Department of Medicinal Chemistry, Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Govt. of India, Sila Katamur (Halugurisuk), P.O.: Changsari, Dist: Kamrup, Pin, National Institute of Pharmaceutical Education and Research, Guwahati, (NIPER Guwahati), Guwahati, Assam, 781101, India.
Publikováno v:
Molecular informatics [Mol Inform] 2024 Oct; Vol. 43 (10), pp. e202400008. Date of Electronic Publication: 2024 Aug 07.
Publikováno v:
Journal of Biological Chemistry. 273:10888-10892
Estrogen sulfotransferase (EST) catalyzes the transfer of the sulfuryl group from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to 17beta-estradiol (E2). The sulfation of E2 prevents it from binding to, and thereby activating, the estrogen receptor. T
Publikováno v:
Diabetes. 40:1360-1363
Publikováno v:
The Biochemical journal. 356(Pt 3)
Sulphation is an important conjugation pathway in drug metabolism that has been studied in several species including humans. However, few studies have been performed using the dog as a subject. In this report we describe the cloning and characterizat
Autor:
C Wooldridge, Guangping Chen, D Zhang, J L York, C N Falany, Anna Radominska-Pandya, P A Rabjohn
Publikováno v:
Biochemistry. 39(51)
The carboxyl-specific amino acid modification reagent, Woodward's reagent K (WK), was utilized to characterize carboxyl residues (Asp and Glu) in the active site of human phenol sulfotransferase (SULT1A1). SULT1A1 was purified using the pMAL-c2 expre
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(9)
The metabolism of the local anesthetics lidocaine and ropivacaine (ropi) involves several steps in humans. Lidocaine is mainly hydrolyzed and hydroxylated to 4-OH-2,6-xylidine (4-OH-xyl). The metabolism of ropi, involving dealkylation and hydroxylati
Publikováno v:
Carcinogenesis. 19(11)
Cooked food mutagens from fried meat and fish have recently been suggested to contribute to the etiology of breast cancer. Thus, the most prevalent of these compounds, i.e. 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, or rather its more mutagenic
Publikováno v:
Chirality. 10(9)
The beta 2-receptor agonist class of drugs is metabolized in humans almost exclusively by sulfate conjugation. The objective of this investigation was to determine the influence of chemical structure on the stereoselectivity of the sulfoconjugation o