Zobrazeno 1 - 10
of 156
pro vyhledávání: '"C Michael, Hart"'
Autor:
Arun Balasubramaniam, Ge Li, Anita Ramanathan, Simon Musyoka Mwangi, C. Michael Hart, Jack L. Arbiser, Shanthi Srinivasan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Enteric neuron degeneration has been observed during aging, and in individuals with metabolic dysfunction including obesity and diabetes. Honokiol, a naturally occurring compound, is an activator of Sirtuin-3 (SIRT3) that has antioxidant act
Externí odkaz:
https://doaj.org/article/9f3ac1106c164679b78f7efd63352a3e
Autor:
Simon Musyoka Mwangi, Ge Li, Arun Balasubramaniam, Didier Merlin, Paul A. Dawson, Young C. Jang, C. Michael Hart, Mark J. Czaja, Shanthi Srinivasan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Nonalcoholic fatty liver disease (NAFLD) is associated with increased oxidative stress that leads to hepatocyte and mitochondrial damage. In this study we investigated the mechanisms involved in the induction of oxidative stress and impairme
Externí odkaz:
https://doaj.org/article/556901cf6394459b8308f062a92d5843
Publikováno v:
Alcohol. 106:30-43
Alcohol use disorders (AUD) cause alveolar macrophage (AM) immune dysfunction and increase risk of lung infections. Excessive alcohol use causes AM oxidative stress which impairs AM phagocytosis and pathogen clearance from the alveolar space. Alcohol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbae4aced6ab1bdac67c561680698aaf
https://doi.org/10.1016/j.alcohol.2022.10.003
https://doi.org/10.1016/j.alcohol.2022.10.003
Autor:
Nicholas M. Maurice, Brahmchetna Bedi, Zhihong Yuan, Kuo-Chuan Lin, Joanna B. Goldberg, C. Michael Hart, Kristina L. Bailey, Ruxana T. Sadikot
Publikováno v:
Pathogens, Vol 11, Iss 2, p 116 (2022)
The innate immune response to P. aeruginosa pulmonary infections relies on a network of pattern recognition receptors, including intracellular inflammasome complexes, which can recognize both pathogen- and host-derived signals and subsequently promot
Externí odkaz:
https://doaj.org/article/582e055f2e2a4cd39af2972c063ee044
Publikováno v:
Pulmonary Circulation, Vol 9 (2019)
Pulmonary hypertension (PH) occurs when the pulmonary vasculature is itself diseased or becomes affected secondarily by comorbid conditions, commonly left heart or lung disease. The high prevalence of chronic cardiopulmonary conditions among patients
Externí odkaz:
https://doaj.org/article/750b734cade54e049285d3c86f2c4be5
Autor:
Xiangqin Cui, Amit J. Shah, Lawrence S. Phillips, David Benkeser, C. Michael Hart, Anna R. Hemnes, Aaron W. Trammell, Julia W. Gallini
Publikováno v:
Chest. 161:803-806
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::974f2f3b01d251acadd4ee72da709c4a
https://doi.org/10.1016/j.chest.2021.09.005
https://doi.org/10.1016/j.chest.2021.09.005
Autor:
Dong Hun Lee, Sarah S. Chang, Minseong Kim, Raham Lee, Andrew J. Jang, Juyoung Kim, Jing Ma, Michael J. Passineau, Raymond L. Benza, Harry Karmouty-Quintana, Wilbur A. Lam, Roy L. Sutliff, C. Michael Hart, Changwon Park, Bum-Yong Kang
Endothelial-to-mesenchymal transition (EndoMT) plays an important role in pulmonary hypertension (PH). Also, the molecular mechanisms regulating EndoMT in PH remain to be defined. In this study, we first showed that reduced expression of the transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca686d31b02ce814867bc409fcfb6411
https://doi.org/10.21203/rs.3.rs-2380412/v1
https://doi.org/10.21203/rs.3.rs-2380412/v1
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
Pulmonary hypertension (PH) is a clinical disorder characterized by sustained increases in pulmonary vascular resistance and pressure that can lead to right ventricular (RV) hypertrophy and ultimately RV failure and death. The molecular pathogenesis
Externí odkaz:
https://doaj.org/article/7708b538aca94d7ca6ea8984648da90f
Publikováno v:
J Immunol
Alcohol use disorders (AUD) increase susceptibility to respiratory infections by 2- to 4-fold in part because of impaired alveolar macrophage (AM) immune function. Alcohol causes AM oxidative stress, diminishing AM phagocytic capacity and clearance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7dbe2c36fa340a9b5cd0b37c014dac5
https://doi.org/10.4049/jimmunol.2000565
https://doi.org/10.4049/jimmunol.2000565
Autor:
Simon Musyoka Mwangi, Ge Li, Arun Balasubramaniam, Didier Merlin, Paul A. Dawson, Young C. Jang, C. Michael Hart, Mark J. Czaja, Shanthi Sriniva
Nonalcoholic fatty liver disease (NAFLD) is associated with increased oxidative stress that leads to hepatocyte and mitochondrial damage. In this study we investigated the mechanisms involved in the induction of oxidative stress and impairment of mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06374d6362c4d06127dbd891530ee5e4
https://doi.org/10.21203/rs.3.rs-1677830/v1
https://doi.org/10.21203/rs.3.rs-1677830/v1