Zobrazeno 1 - 10
of 77
pro vyhledávání: '"C Mebus"'
Autor:
Bruna G. Sousa, Nathane C. Mebus-Antunes, Lorena O. Fernandes-Siqueira, Marjolly B. Caruso, Georgia N. Saraiva, Clara F. Carvalho, Thais C. Neves-Martins, Antonio Galina, Russolina B. Zingali, Julianna D. Zeidler, Andrea T. Da Poian
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT Dengue virus (DENV) infection is known to affect host cell metabolism, but the molecular players involved are still poorly known. Using a proteomics approach, we identified six DENV proteins associated with mitochondria isolated from infecte
Externí odkaz:
https://doaj.org/article/dd4c809aefcf4eadab15b8b1bed2a978
Autor:
Lorena O. Fernandes-Siqueira, Fabiana A. P. Ferreira, Bruna G. Sousa, Nathane C. Mebus-Antunes, Thais C. Neves-Martins, Fabio C. L. Almeida, Gustavo C. Ferreira, Didier Salmon, Luciana S. Wermelinger, Andrea T. Da Poian
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The Covid-19 pandemic, caused by SARS-CoV-2, has resulted in over 6 million reported deaths worldwide being one of the biggest challenges the world faces today. Here we present optimizations of all steps of an enzyme-linked immunosorbent ass
Externí odkaz:
https://doaj.org/article/3b2218a2321c433fbb4b44938012e554
Autor:
Thais C. Neves-Martins, Nathane C. Mebus-Antunes, Carlos H.G. Neto, Glauce M. Barbosa, Fabio C.L. Almeida, Icaro P. Caruso, Andrea T. Da Poian
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106197- (2023)
Summary: Nucleocapsid (NC) assembly is an essential step of the virus replication cycle. It ensures genome protection and transmission among hosts. Flaviviruses are human viruses for which envelope structure is well known, whereas no information on N
Externí odkaz:
https://doaj.org/article/308c5dd8cc91422d955ed3d55a7cf83e
Autor:
Liliane O. Ortlieb, Ícaro P. Caruso, Nathane C. Mebus-Antunes, Andrea T. Da Poian, Elaine da C. Petronilho, José Daniel Figueroa-Villar, Claudia J. Nascimento, Fabio C. L. Almeida
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 287-298 (2022)
We synthesised and screened 18 aromatic derivatives of guanylhydrazones and oximes aromatic for their capacity to bind to dengue virus capsid protein (DENVC). The intended therapeutic target was the hydrophobic cleft of DENVC, which is a region respo
Externí odkaz:
https://doaj.org/article/ded108e4fe594222bc011e4fbb359cf6
Autor:
Nathane C Mebus-Antunes, Wellington S Ferreira, Glauce M Barbosa, Thais C Neves-Martins, Gilberto Weissmuller, Fabio C L Almeida, Andrea T Da Poian
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0264643 (2022)
Dengue virus (DENV) causes a major arthropod-borne viral disease, with 2.5 billion people living in risk areas. DENV consists in a 50 nm-diameter enveloped particle in which the surface proteins are arranged with icosahedral symmetry, while informati
Externí odkaz:
https://doaj.org/article/a3a7e8867efa41f88d27e5cd8f7fd7d4
Autor:
Ícaro Putinhon Caruso, Fabio C. L. Almeida, Thais Cristtina Neves-Martins, Nathane C. Mebus-Antunes, Andrea T. Da Poian
Publikováno v:
Current Opinion in Virology. 47:106-112
The Flaviviridae family comprises important human pathogens, including Dengue, Zika, West Nile, Yellow Fever and Japanese Encephalitis viruses. The viral genome, a positive-sense single-stranded RNA, is packaged by a single protein, the capsid protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34193e0c0cd73d5179476945c16905c
https://doi.org/10.1016/j.coviro.2021.02.005
https://doi.org/10.1016/j.coviro.2021.02.005
Autor:
Liliane O. Ortlieb, Ícaro P. Caruso, Nathane C. Mebus-Antunes, Andrea T. Da Poian, Elaine da C. Petronilho, José Daniel Figueroa-Villar, Claudia J. Nascimento, Fabio C. L. Almeida
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 287-298 (2022)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 287-298 (2022)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-29T08:37:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01 We synthesised and screened 18 aromatic derivatives of guanylhydrazones and oximes aromatic for their capacity to bind to dengue virus capsid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff60937b38568356ce3cd37d9634e3a0
https://pubmed.ncbi.nlm.nih.gov/34894959
https://pubmed.ncbi.nlm.nih.gov/34894959
Autor:
Thais Cristtina Neves-Martins, Aline de Luna Marques, Gabriela R. Araujo, Mariana J. do Amaral, Isabella Otenio de Lourenço, Vitor S. Almeida, Ícaro Putinhon Caruso, Francisco Gomes-Neto, Guilherme Caldas Andrade, Andrea T. Da Poian, Talita S. Araujo, Glauce M. Barbosa, Karoline Sanches, Ariana A. Vasconcelos, Clara L. F. Malizia-Motta, Katia M. S. Cabral, Peter Reis Bezerra, Marcos Caique Santana-Silva, Nathane C. Mebus-Antunes, Jessica M. Azevedo, Cristiane D. Anobom, Leonardo Bartkevihi, Gisele Cardoso Amorim, Fabio C. L. Almeida, Jessica M. Sa, Anderson S. Pinheiro, Marcius S. Almeida
The SARS-CoV-2 nucleocapsid protein (N) is a multifunctional promiscuous nucleic acid-binding protein, which plays a major role in nucleocapsid assembly and discontinuous RNA transcription, facilitating the template switch of transcriptional regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ba4092d34b6208964bdc927921ac0ff
https://doi.org/10.1101/2021.07.21.453232
https://doi.org/10.1101/2021.07.21.453232
Publikováno v:
International journal of oral and maxillofacial surgery. 47(5)
The objective of this study was to propose a treatment protocol for patients with lateral prognathism based on the unilateral sagittal split ramus osteotomy (USSRO). This was a prospective study involving 31 patients with lateral prognathism, who req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f7afe3e7b378768b2baff84fd89ba0
https://pubmed.ncbi.nlm.nih.gov/29223700
https://pubmed.ncbi.nlm.nih.gov/29223700
Autor:
M M, Hutmacher, K, Papp, S, Krishnaswami, K, Ito, H, Tan, R, Wolk, H, Valdez, C, Mebus, S T, Rottinghaus, P, Gupta
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
Tofacitinib is an oral Janus kinase inhibitor. An integrated analysis was conducted to evaluate dosage optimality for tofacitinib in patients with moderate‐to‐severe plaque psoriasis and the impact of body weight on optimality in this patient pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba783e3b5b4b903d003c872ef714060d
https://pubmed.ncbi.nlm.nih.gov/28317328
https://pubmed.ncbi.nlm.nih.gov/28317328