Zobrazeno 1 - 10
of 445
pro vyhledávání: '"C Mazurier"'
Publikováno v:
ISBT Science Series. 11:111-117
Transfusion needs are diversely fulfilled globally. Besides, with population ageing, the various problems faced by healthcare systems will become more and more prominent. As a consequence, the current model of blood supply has to be strengthened, and
Autor:
L. Douay, C. Mazurier
Publikováno v:
Revue d'Oncologie Hématologie Pédiatrique. 2:141-149
Resume L’accroissement et le vieillissement de la population mondiale conduiront dans les prochaines decennies a une augmentation de l’incidence des pathologies necessitant un support transfusionnel, et parallelement diminueront la proportion de
Autor:
C. Mazurier, L. Douay
Publikováno v:
ISBT Science Series. 8:137-141
The present paper reports the various obstacles cleared during the past decade with the view of generating red blood cells in vitro from various sources of stem cells, for transfusion purposes. We also consider the next developments to be performed f
Autor:
L. Douay, C. Mazurier
Publikováno v:
Transfusion Clinique et Biologique. 20:90-94
In vitro generation of red blood cells (RBC) makes sense in a context of recurrent shortage. It could be an interesting complementary source for "classic" transfusion products by combining the sufficiency of supply, homemade production of a particula
Publikováno v:
Clinical & Laboratory Haematology. 6:193-197
Publikováno v:
Journal of stem cellsregenerative medicine. 6(2)
Autor:
C. Mazurier, Edith Fressinaud, J. Goudemand, Christine Gaucher, Sylvie Jorieux, Dominique Meyer
Publikováno v:
Blood. 95:3139-3145
We report 2 new mutations identified in 3 patients and characterized by the markedly decreased affinity of von Willebrand factor (vWF) for factor VIII (FVIII). Patients 2 and 3, who have a typical type 2N phenotype, were found to be compound heterozy
Autor:
J. A. Van Mourik, C. Mazurier, Patrick H.N. Celie, S. Jorieux, Koen Mertens, G. Van Stempvoort
Publikováno v:
British Journal of Haematology. 106:792-800
The functional defect caused by substitution of Arg527 (--> Trp) and Arg531 (--> Gly, His) in factor VIII (FVIII), was explored by employing FVIII derived from patient plasma and recombinant FVIII variants. Mutation of these residues is associated wi
Publikováno v:
Blood. 92:4663-4670
In type 2N von Willebrand disease (vWD), von Willebrand factor (vWF) is characterized by normal multimeric pattern, normal platelet-dependent function, but a markedly decreased affinity for factor VIII (FVIII). In this report, we describe the case of
Autor:
C Mazurier
Publikováno v:
Haemophilia. 4:40-43
The structural and functional studies of the concentrate of von Willebrand factor (vWF) manufactured by LFB have been first performed as part of the preclinical development of this product specially intended for the treatment of von Willebrand diseas