Zobrazeno 1 - 10
of 37
pro vyhledávání: '"C Marcelo Sergio"'
Autor:
David Gallego-Ortega, Anita Ledger, Daniel L Roden, Andrew M K Law, Astrid Magenau, Zoya Kikhtyak, Christina Cho, Stephanie L Allerdice, Heather J Lee, Fatima Valdes-Mora, David Herrmann, Robert Salomon, Adelaide I J Young, Brian Y Lee, C Marcelo Sergio, Warren Kaplan, Catherine Piggin, James R W Conway, Brian Rabinovich, Ewan K A Millar, Samantha R Oakes, Tatyana Chtanova, Alexander Swarbrick, Matthew J Naylor, Sandra O'Toole, Andrew R Green, Paul Timpson, Julia M W Gee, Ian O Ellis, Susan J Clark, Christopher J Ormandy
Publikováno v:
PLoS Biology, Vol 13, Iss 12, p e1002330 (2015)
During pregnancy, the ETS transcription factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of the mammary luminal progenitor cell. In breast cancer, ELF5 is a key transcriptional determinant of tumor subt
Externí odkaz:
https://doaj.org/article/eb537bc34b10404fbde06ea888ba833f
Autor:
Elizabeth A Musgrove, C Marcelo Sergio, Sherene Loi, Claire K Inman, Luke R Anderson, M Chehani Alles, Mark Pinese, C Elizabeth Caldon, Judith Schütte, Margaret Gardiner-Garden, Christopher J Ormandy, Grant McArthur, Alison J Butt, Robert L Sutherland
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2987 (2008)
BACKGROUND: Estrogen is a pivotal regulator of cell proliferation in the normal breast and breast cancer. Endocrine therapies targeting the estrogen receptor are effective in breast cancer, but their success is limited by intrinsic and acquired resis
Externí odkaz:
https://doaj.org/article/9015bd05c2a54490bfb15d6d943946a8
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 80KB, The effect of BI2536 in endocrine-sensitive and endocrine-resistant breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48de6ce62c37be717935252685c4307a
https://doi.org/10.1158/1535-7163.22499772.v1
https://doi.org/10.1158/1535-7163.22499772.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 41KB, Supplementary Figure 3: Effect of overexpression of cyclins E1 and E2 on antiestrogen-induced growth arrest. T-47D cells overexpressing cyclin E1, cyclin E2 or vector control were treated with fulvestrant or vehicle. Densitometry of W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b56fdd7b8ef1692d5996ff085c1d435
https://doi.org/10.1158/1535-7163.22496367
https://doi.org/10.1158/1535-7163.22496367
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
Cyclin E2, but not cyclin E1, is included in several gene signatures that predict disease progression in either tamoxifen-resistant or metastatic breast cancer. We therefore examined the role of cyclin E2 in antiestrogen resistance in vitro and its p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c5f42b0999852523b1d14a21695d2c
https://doi.org/10.1158/1535-7163.c.6535245.v1
https://doi.org/10.1158/1535-7163.c.6535245.v1
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 221KB, A. Plk1 Expression vs relapse-free survival in endocrine treated ER-positive breast cancer patients (n=287). B. Correlative analysis of ER, BCL-2 and PLK1 gene expression in TCGA breast cohort (n=774).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2017fdbbb2b1d07e283ecb30798a51fe
https://doi.org/10.1158/1535-7163.22499778.v1
https://doi.org/10.1158/1535-7163.22499778.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 56KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c981343b4d6da4a0978ea17836b2e6
https://doi.org/10.1158/1535-7163.22496364.v1
https://doi.org/10.1158/1535-7163.22496364.v1
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 289KB, BCL-2 450K Methylation array probes (n=42).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af155d65b15d794f7dcf5f2211bbdab
https://doi.org/10.1158/1535-7163.22499790.v1
https://doi.org/10.1158/1535-7163.22499790.v1
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
Overexpression of the antiapoptotic factor BCL-2 is a frequent feature of malignant disease and is commonly associated with poor prognosis and resistance to conventional chemotherapy. In breast cancer, however, high BCL-2 expression is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2063975ae1d6d5bbfc9b403a0b5a112a
https://doi.org/10.1158/1535-7163.c.6536253
https://doi.org/10.1158/1535-7163.c.6536253
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 664KB, BCL-2 Gene expression vs methylation status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a71ba8bf6e02ee496d901e53c9767a
https://doi.org/10.1158/1535-7163.22499787.v1
https://doi.org/10.1158/1535-7163.22499787.v1