Zobrazeno 1 - 10
of 47
pro vyhledávání: '"C Marcelo Sergio"'
Autor:
Diar Aziz, Neil Portman, Kristine J. Fernandez, Christine Lee, Sarah Alexandrou, Alba Llop-Guevara, Zoe Phan, Aliza Yong, Ashleigh Wilkinson, C. Marcelo Sergio, Danielle Ferraro, Dariush Etemadmoghadam, David D. Bowtell, kConFab Investigators, Violeta Serra, Paul Waring, Elgene Lim, C. Elizabeth Caldon
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Basal-like breast cancers (BLBC) are aggressive breast cancers that respond poorly to targeted therapies and chemotherapies. In order to define therapeutically targetable subsets of BLBC we examined two markers: cyclin E1 and BRCA1 loss. In
Externí odkaz:
https://doaj.org/article/6daf1a428240435b83fc21ea45524a31
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 80KB, The effect of BI2536 in endocrine-sensitive and endocrine-resistant breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48de6ce62c37be717935252685c4307a
https://doi.org/10.1158/1535-7163.22499772.v1
https://doi.org/10.1158/1535-7163.22499772.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 41KB, Supplementary Figure 3: Effect of overexpression of cyclins E1 and E2 on antiestrogen-induced growth arrest. T-47D cells overexpressing cyclin E1, cyclin E2 or vector control were treated with fulvestrant or vehicle. Densitometry of W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b56fdd7b8ef1692d5996ff085c1d435
https://doi.org/10.1158/1535-7163.22496367
https://doi.org/10.1158/1535-7163.22496367
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
Cyclin E2, but not cyclin E1, is included in several gene signatures that predict disease progression in either tamoxifen-resistant or metastatic breast cancer. We therefore examined the role of cyclin E2 in antiestrogen resistance in vitro and its p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c5f42b0999852523b1d14a21695d2c
https://doi.org/10.1158/1535-7163.c.6535245.v1
https://doi.org/10.1158/1535-7163.c.6535245.v1
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 221KB, A. Plk1 Expression vs relapse-free survival in endocrine treated ER-positive breast cancer patients (n=287). B. Correlative analysis of ER, BCL-2 and PLK1 gene expression in TCGA breast cohort (n=774).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2017fdbbb2b1d07e283ecb30798a51fe
https://doi.org/10.1158/1535-7163.22499778.v1
https://doi.org/10.1158/1535-7163.22499778.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 56KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c981343b4d6da4a0978ea17836b2e6
https://doi.org/10.1158/1535-7163.22496364.v1
https://doi.org/10.1158/1535-7163.22496364.v1
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 289KB, BCL-2 450K Methylation array probes (n=42).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af155d65b15d794f7dcf5f2211bbdab
https://doi.org/10.1158/1535-7163.22499790.v1
https://doi.org/10.1158/1535-7163.22499790.v1
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
Overexpression of the antiapoptotic factor BCL-2 is a frequent feature of malignant disease and is commonly associated with poor prognosis and resistance to conventional chemotherapy. In breast cancer, however, high BCL-2 expression is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2063975ae1d6d5bbfc9b403a0b5a112a
https://doi.org/10.1158/1535-7163.c.6536253
https://doi.org/10.1158/1535-7163.c.6536253
Autor:
Elizabeth A. Musgrove, Susan J. Clark, Cristin G. Print, Robert I. Nicholson, Julia M.W. Gee, Andrew V. Biankin, Christopher J. Ormandy, C. Elizabeth Caldon, David Gallego-Ortega, C. Marcelo Sergio, Rachael A. McCloy, Fatima Valdes-Mora, Mark J. Cowley, Andrew Stone
PDF - 664KB, BCL-2 Gene expression vs methylation status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a71ba8bf6e02ee496d901e53c9767a
https://doi.org/10.1158/1535-7163.22499787.v1
https://doi.org/10.1158/1535-7163.22499787.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 929KB, Supplementary Figure 1: Cyclin E2 association with breast cancer subtype, grade, and outcome. A: Relationship between a second cyclin E2 probeset and breast cancer subtype, or histological grade. Box: upper and lower quartiles; divid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd6eafb562fc2e57bc31afce5e5f10f
https://doi.org/10.1158/1535-7163.22496373.v1
https://doi.org/10.1158/1535-7163.22496373.v1