Zobrazeno 1 - 10
of 1 806
pro vyhledávání: '"C Mackay"'
Autor:
Katelynne M. Collins, Elisabeth Howansky, Sarah C. Macon-Foley, Maria E. Adonay, Vijay Shankar, Richard F. Lyman, Nestor Octavio Nazario-Yepiz, Jordyn K. Brooks, Rachel A. Lyman, Trudy F. C. Mackay, Robert R. H. Anholt
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-14 (2024)
Abstract Background 4-methylimidazole is a ubiquitous and potentially carcinogenic environmental toxicant. Genetic factors that contribute to variation in susceptibility to its toxic effects are challenging to assess in human populations. We used the
Externí odkaz:
https://doaj.org/article/e59933fe43b04c80965ccab72c2b6d57
Autor:
L.K. King, A. Mahmoudian, E.J. Waugh, I. Stanaitis, M. Gomes, V. Hung, C. MacKay, J.W. Liew, Q. Wang, A. Turkiewicz, I.K. Haugen, C.T. Appleton, S. Lohmander, M. Englund, J. Runhaar, T. Neogi, G.A. Hawker
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 1, Pp 100428- (2024)
Objective: As part of the first phase of the OARSI Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) initiative, we explored the first symptoms and experiences recalled by individuals with knee osteoarthritis (OA). Design: This qualitative study,
Externí odkaz:
https://doaj.org/article/995b3deb1ed04a27b4273baa967b5ca4
Autor:
Rebecca A. MacPherson, Vijay Shankar, Lakshmi T. Sunkara, Rachel C. Hannah, Marion R. Campbell, Robert R. H. Anholt, Trudy F. C. Mackay
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Long noncoding RNAs (lncRNAs) are a diverse class of RNAs that are critical for gene regulation, DNA repair, and splicing, and have been implicated in development, stress response, and cancer. However, the functions of many lncRNA
Externí odkaz:
https://doaj.org/article/b1d2d8783ff94f748bf10ce0fadd66ad
Autor:
Tatiana V. Morozova, Vijay Shankar, Rebecca A. MacPherson, Trudy F. C. Mackay, Robert R. H. Anholt
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Prenatal exposure to ethanol can cause fetal alcohol spectrum disorder (FASD), a prevalent, preventable pediatric disorder. Identifying genetic risk alleles for FASD is challenging since time, dose, and frequency of exposure are o
Externí odkaz:
https://doaj.org/article/876d9492f3854dbea9c5a7739bab832f
Autor:
Spencer B. Huggett, Jeffrey S. Hatfield, Joshua D. Walters, John E. McGeary, Justine W. Welsh, Trudy F. C. Mackay, Robert R. H. Anholt, Rohan H. C. Palmer
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Cocaine use presents a worldwide public health problem with high socioeconomic cost. No current pharmacologic treatments are available for cocaine use disorder (CUD) or cocaine toxicity. To explore pharmaceutical treatments for tthis disorde
Externí odkaz:
https://doaj.org/article/7de996ed1d7d4465a6822ead3a34259a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 2 (2022)
AbstractInsect odorant-binding proteins (OBPs) are members of a rapidly evolving multigene family traditionally thought to facilitate chemosensation. However, studies on DrosophilaObp56hD. melanogaster ObpCas9Obp56hObp56h−/−Obp56h−/−Obp56h−
Externí odkaz:
https://doaj.org/article/4127d9ea3e904d8080f458046b724157
Publikováno v:
PLoS Biology, Vol 20, Iss 7 (2022)
Gregor Mendel’s discovery of the laws of segregation and independent assortment and his inference of the existence of non-mendelian interactions between loci remain at the heart of today’s explorations of the genetic architecture of quantitative
Externí odkaz:
https://doaj.org/article/4e4c054fc7d747c28a50ebcca99c2c9d
Autor:
P. Horwich, C. MacKay, M. Bullock, S. M. Taylor, R. Hart, J. Trites, L. Geldenhuys, B. Williams, M. H. Rigby
Publikováno v:
Journal of Otolaryngology - Head and Neck Surgery, Vol 50, Iss 1, Pp 1-12 (2021)
Abstract Objective Evaluate the oncologic outcomes and cost analysis of transitioning to a specimen oriented intraoperative margin assessment protocol from a tumour bed sampling protocol in oral cavity (OCSCC) and oropharyngeal squamous cell carcinom
Externí odkaz:
https://doaj.org/article/f5c58093faee4c83b69d1a01776e738d
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4599-4613 (2020)
Externí odkaz:
https://doaj.org/article/a1829675b613420a86b2cd7ce9e58155
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Huang et al. show that developing under different temperatures changes the genetic architecture of regulatory variation in Drosophila melanogaster gene expression yet the co-expression network remains robust. Data suggest that stabilizing selection o
Externí odkaz:
https://doaj.org/article/6a61c4dc8259471cb7b8dcfc716eb7c7