Zobrazeno 1 - 10
of 12
pro vyhledávání: '"C M Zacharchuk"'
Publikováno v:
The Journal of Immunology. 149:1825-1852
Ly-6A/E molecules were originally implicated in regulation of T cell activation because anti-Ly-6A/E mAb induce IL-2 production. More recently we have shown that anti-Ly-6A/E also inhibits IL-2 production induced by anti-CD3. In the present study we
Publikováno v:
The Journal of Immunology. 147:460-465
Activation of immature thymocytes via the TCR results in programmed cell death and clonal deletion. We have examined thymocytes from mice of different ages and observed that, whereas TCR-mediated signaling caused deletion of thymocytes from newborn a
Publikováno v:
The Journal of Immunology. 145:4037-4045
Both cellular activation signals and exposure to glucocorticoids such as dexamethasone (Dex) cause programmed cell death in T cell hybridomas. When cells were activated in the presence of Dex, however, the degree of killing that was achieved by eithe
Publikováno v:
The Journal of biological chemistry. 271(48)
Bcl-2 is a cytoplasmic integral membrane protein with potent anti-apoptotic activity but whose mechanism of action is poorly understood. The purpose of this paper was to obtain large amounts of soluble Bcl-2 protein for structural and functional stud
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(5)
Expression of the transcription complex AP-1, composed of Jun and Fos family members, can be induced by a variety of stimuli. In lymphocytes, AP-1 transcriptional activity increases after TCR ligation and plays an important role in T cell activation
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 149(6)
Ly-6A/E molecules were originally implicated in regulation of T cell activation because anti-Ly-6A/E mAb induce IL-2 production. More recently we have shown that anti-Ly-6A/E also inhibits IL-2 production induced by anti-CD3. In the present study we
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(2)
Activation of immature thymocytes via the TCR results in programmed cell death and clonal deletion. We have examined thymocytes from mice of different ages and observed that, whereas TCR-mediated signaling caused deletion of thymocytes from newborn a
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(12)
Both cellular activation signals and exposure to glucocorticoids such as dexamethasone (Dex) cause programmed cell death in T cell hybridomas. When cells were activated in the presence of Dex, however, the degree of killing that was achieved by eithe
Publikováno v:
The Journal of Immunology. 131:2362-2367
Peritoneal macrophages from C3HeB/FeJ mice became cytotoxic for 6C3HED lymphosarcoma cells, P815 mastocytoma cells, and L-929 fibroblasts when treated with the calcium ionophore, A23187, at concentrations ranging from 1.0 to 20 microM. The effect of
Publikováno v:
Methods in enzymology. 132