Zobrazeno 1 - 10
of 178
pro vyhledávání: '"C M Morris"'
Autor:
Michelle A. Lawson, Jennifer M. Down, Lisa J. Crawford, Dharminder Chauhan, Andrew D Chantry, Claudia Hamilton, Jonathan J. Morgan, Treen C. M. Morris, Krishnaraj Rajalingam, Alexandra E. Irvine, Roisin McAvera, Aswini Krishnan, David Campbell
Publikováno v:
Oncogene
Crawford, L J, Campbell, D C, Morgan, J J, Lawson, M A, Down, J M, Chauhan, D, McAvera, R M, Morris, T C, Hamilton, C, Krishnan, A, Rajalingam, K, Chantry, A D & Irvine, A E 2020, ' The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in Multiple Myeloma ', Oncogene, vol. 39, pp. 5001–5014 . https://doi.org/10.1038/s41388-020-1345-x
Crawford, L J, Campbell, D C, Morgan, J J, Lawson, M A, Down, J M, Chauhan, D, McAvera, R M, Morris, T C, Hamilton, C, Krishnan, A, Rajalingam, K, Chantry, A D & Irvine, A E 2020, ' The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in Multiple Myeloma ', Oncogene, vol. 39, pp. 5001–5014 . https://doi.org/10.1038/s41388-020-1345-x
Proteasome inhibitors have provided a significant advance in the treatment of multiple myeloma (MM). Consequently, there is increasing interest in developing strategies to target E3 ligases, de-ubiquitinases, and/or ubiquitin receptors within the ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37220f16bcd269c548b5b079bcc895e5
http://europepmc.org/articles/PMC7329634
http://europepmc.org/articles/PMC7329634
Autor:
John A, Snowden, Sam H, Ahmedzai, Angela, Cox, David A, Cairns, A John, Ashcroft, Cathy, Williams, Jamie D, Cavenagh, Anna, Hockaday, Julia M, Brown, Ian W, Brock, Treen C M, Morris, Gordon, Cook
Publikováno v:
Bone marrow transplantation. 57(10)
The Myeloma X trial provided a platform to explore genetics in relation to systematic assessment of patient-reported outcomes at key points during salvage treatment in multiple myeloma (MM) patients. Blood DNA was obtained in 191 subjects for single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90aed5c4b9219940cd26105db060a2c0
https://pubmed.ncbi.nlm.nih.gov/35768571
https://pubmed.ncbi.nlm.nih.gov/35768571
Autor:
Padimac investigators, Laura Clifton-Hadley, Dunnya De-Silva, Treen C. M. Morris, Nicholas Counsell, Wei Yee Chan, Elizabeth H Phillips, Neil Rabin, Roger G. Owen, Gordon Cook, Rakesh Popat, Jamie Cavenagh, Ruth M. de Tute, Matthew Streetly, Mickey Koh, Nivette Braganca, Josephine Crowe, Kwee Yong, Stephen Schey, Toyin Adedayo, Claire Roddie
Publikováno v:
British Journal of Haematology. 196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9900443f58e6b291b392e879118cad73
https://doi.org/10.1111/bjh.17903
https://doi.org/10.1111/bjh.17903
Publikováno v:
Analytical Cellular Pathology, Vol 25, Iss 4, Pp 167-171 (2003)
Direct measurement of monoclonal plasma cell mass in bone marrow biopsies may be a useful parameter to establish in plasma cell dyscrasia. In this study monoclonal plasma cells/mm2 in light chain immunoglobulin immunostained archival bone marrow sect
Externí odkaz:
https://doaj.org/article/81970d84fab24a24979ddc8731ece5da
Autor:
Sam H, Ahmedzai, John A, Snowden, Andrew John, Ashcroft, David Allan, Cairns, Cathy, Williams, Anna, Hockaday, Jamie D, Cavenagh, Debo, Ademokun, Eleni, Tholouli, David, Allotey, Vijay, Dhanapal, Matthew, Jenner, Kwee, Yong, Jim, Cavet, Hannah, Hunter, Jennifer M, Bird, Guy, Pratt, Christopher, Parrish, Julia M, Brown, Treen C M, Morris, Gordon, Cook
Publikováno v:
Journal of Clinical Oncology
J Clin Oncol
J Clin Oncol
PURPOSE Salvage autologous stem-cell transplantation (sASCT) in patients with multiple myeloma (MM) relapsing after a prior autologous stem-cell transplantation leads to increased remission duration and overall survival. We report a comprehensive stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e15f1f463ef2d3739c6f7580bc853ef4
http://europepmc.org/articles/PMC6858007
http://europepmc.org/articles/PMC6858007
Autor:
Treen C. M. Morris, Josephine Crowe, Elizabeth H Phillips, Kwee Yong, Jamie Cavenagh, Toyin Adedayo, Mickey Koh, Claire Roddie, Laura Clifton-Hadley, Steve Schey, Dunnya De-Silva, Gordon Cook, Ruth M. de Tute, Matthew Streetly, Paul Smith, Nivette Braganca, Rakesh Popat, Nicholas Counsell, Neil Rabin, Roger G. Owen
Publikováno v:
Popat, R, Counsell, N, Tute, R D, De-Silva, D, Phillips, E H, Cavenagh, J D, Adedayo, T, Braganca, N, Roddie, C, Streetly, M, Schey, S, Koh, M B C, Crowe, J, Morris, T C, Cook, G, Smith, P, Clifton-Hadley, L, Rabin, N, Owen, R G & Yong, K 2021, ' Using depth of response to stratify patients to front line Autologous Stem Cell Transplant: results of the phase II PADIMAC Myeloma Trial ', British Journal of Haematology, vol. 193, no. 3, pp. e19-e22 . https://doi.org/10.1111/bjh.17391
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a2e1492f73084d9edf3e4a2a1318fd
https://doi.org/10.1111/bjh.17391
https://doi.org/10.1111/bjh.17391
Autor:
David A Cairns, Alberto Alvarez-Iglesias, Helen Enright, Tracey McGuigan, M. Drake, Gordon Cook, Rakesh Popat, Heather Oakervee, Jamie Cavenagh, Tanya O’Shea, Maeve Leahy, P Kettle, Michael O'Dwyer, Treen C. M. Morris, Kwee Yong
Publikováno v:
Morris, T C M, Drake, M B, Kettle, P J, McGuigan, T, Leahy, M, O'Dwyer, M, Enright, H, O'Shea, T, Popat, R, Oakervee, H E, Yong, K, Cavenagh, J D, Cairns, D A, Alvarez-Iglesias, A & Cook, G 2021, ' How to Simplify the Evaluation of Newly Introduced Chemotherapeutic Interventions in Myeloma ', Clinical hematology international, vol. 3, no. 1, pp. 27-33 . https://doi.org/10.2991/chi.k.210201.001
Clinical Hematology International, Vol 3, Iss 1 (2021)
Clinical Hematology International
Clinical Hematology International, Vol 3, Iss 1 (2021)
Clinical Hematology International
When the bortezomib [PS341], adriamycin and dexamethasone (PAD) regimen was first evaluated, the response rate in untreated patients was much superior to that elicited by conventional chemotherapeutic agents. We demonstrated the efficacy of PAD in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5de9777f3b787aeec01a78b049bf23
https://pure.qub.ac.uk/en/publications/f92919e9-c0f1-4ad7-83d8-287eab7c95c1
https://pure.qub.ac.uk/en/publications/f92919e9-c0f1-4ad7-83d8-287eab7c95c1
Autor:
Tyrel M. McQueen, Jason W. Krizan, C. M. Morris, J. Viirok, N. P. Armitage, Nisheeta Desai, Ribhu K. Kaul, Toomas Rõõm, Urmas Nagel, D. Hüvonen, Robert J. Cava, Seyed Koohpayeh
The Ising chain in transverse field is a paradigmatic model for a host of physical phenomena, including spontaneous symmetry breaking, topological defects, quantum criticality, and duality. Although the quasi-1D ferromagnet CoNb$_2$O$_6$ has been put
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8460b40c48863fc7131571cdd6077b
Autor:
N. P. Armitage, C. M. Morris, Seyed Koohpayeh, Tyrel M. McQueen, Nicholas Laurita, W. A. Phelan
Publikováno v:
Physica B: Condensed Matter. 536:78-84
Recent experiments have uncovered evidence of low energy excitations in the bulk of SmB 6 that are perhaps associated with unconventional quasiparticles, bringing into question whether this Kondo “insulator” is truly insulating in the bulk. Recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8845987c26becf1d524eb18a6b8e5a2
https://doi.org/10.1016/j.physb.2017.09.015
https://doi.org/10.1016/j.physb.2017.09.015
Publikováno v:
Parkinson's Disease, Vol 2011 (2011)
Parkinson's disease (PD) is a progressive, neurodegenerative condition that has increasingly been linked with mitochondrial dysfunction and inhibition of the electron transport chain. This inhibition leads to the generation of reactive oxygen species
Externí odkaz:
https://doaj.org/article/249dc9aa3f4a4c7cb904a4eb9fff2c46