Zobrazeno 1 - 10
of 1 038
pro vyhledávání: '"C M Lockwood"'
Autor:
E. Pettersson, Allan Wiik, E. C. Hagen, Konrad Andrassy, Loïc Guillevin, Franco Ferrario, J. Dadonlené, Ulrich Specks, Charles D. Pusey, Athanasios G. Tzioufas, Wolfgang L. Gross, Gina Gregorini, Kerstin Westman, D. R. W. Jayne, Conleth Feighery, C. G. M. Kallenberg, L. A. Van Es, P. Lesavre, Daniel Abramowicz, Raashid Luqmani, G. Gaskin, P. Landais, Eduardo Mirapeix, J. Hermans, C. Grönhagen‐Riska, Niels Rasmussen, K de Groot, F. J. Van Der Woude, C. M. Lockwood, Z. Heigl, J. W. Cohen Tervaert, Renato Alberto Sinico, Paul A. Bacon, Caroline O. S. Savage
In previous phases of this project, proteinase 3 (PR3) and myeloperoxidase (MPO), the main antigenic target molecules of antineutrophil cytopiasmic antibodies, were isolated and applied in standardized ELISAs. In this study, standardized ELISAs with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b8a2f32e3ebc7b00f2f894f8bbd702
https://ora.ox.ac.uk/objects/uuid:c7fcd0e9-1601-4b9e-a40f-cb4b669ad36a
https://ora.ox.ac.uk/objects/uuid:c7fcd0e9-1601-4b9e-a40f-cb4b669ad36a
Plasma exchange was introduced by us in 1974 to achieve rapid elimination of circulating auto-antibodies in patients with rapidly progressive glomerulonephritis. This approach had theoretical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ca563eac8cf46b9e52b1919df26cee
https://doi.org/10.1159/000409379
https://doi.org/10.1159/000409379
Autor:
N R Carroll, David A. Lomas, D Bilton, D B Whitehouse, R I Ross-Russell, R C Westerbeek, L Sharples, C M Lockwood, A C Dunn, A K Webb, Ravi Mahadeva
Publikováno v:
Clinical and Experimental Immunology. 117:561-567
SUMMARY Persistent infection with Pseudomonas aeruginosa and inflammatory mechanisms play an important role in cystic fibrosis (CF) lung disease. ANCA against BPI, a potent host defence protein with anti-bacterial and anti-endotoxin properties, have
Autor:
Brownlee Aa, C. M. Lockwood
Publikováno v:
Clinical and Experimental Immunology. 117:183-189
SUMMARYHeat treatment of normal sera to 56°C for 30 min, a common procedure for the inactivation of viruses, e.g. HIV, reveals the presence of antibodies to neutrophil cytoplasm antigens (ANCA), as detected by indirect immunofluorescence on ethanol-
Publikováno v:
Journal of Immunological Methods. 205:127-133
Anti-neutrophil cytoplasmic antibodies (ANCA) against native bactericidal/permeability-increasing protein (nBPI) have gained increasing diagnostic significance in inflammatory bowel disease and cystic fibrosis. However, routine detection of BPI-ANCA
Autor:
I. Fisch, C. M. Lockwood, James D. Marks, R. Finnern, E. Pedrollo, Willem H. Ouwehand, J. Wieslander
Publikováno v:
Clinical and Experimental Immunology. 107:269-281
SUMMARY This is the first study describing recombinant human antibody fragments directed to the autoantigen proteinase 3 (PR3) from an immune B cell source. Detection of these autoantibodies has proven valid for the diagnosis and monitoring of Wegene
Autor:
Roy E. Pounder, A Brownlee, R S Walmsley, Mark I. Hamilton, Andrew J. Wakefield, C. M. Lockwood, M H Zhao, P Chapman
Publikováno v:
Gut. 40:105-109
BACKGROUND: Bactericidal/permeability-increasing protein (BPI), a constituent of primary neutrophil granules, is a potent natural antibiotic and an antineutrophil cytoplasm antibody (ANCA) antigen in cases of vasculitis in which the target antigen is
Autor:
Elena Csernok, Eduardo Mirapeix, Niels Rasmussen, Bettina E. Hansen, Konrad Andrassy, Jens Lüdemann, Athanasios G. Tzioufas, Allan Wiik, Charles D. Pusey, M. R. Daha, C. M. Lockwood, E. C. Hagen, F. Mascart-Lemone, D. R. W. Jayne, Jos Hermans, Jörgen Wieslander, C. G. M. Kallenberg, P. Lesavre, Z. Heigl, Wolfgang L. Gross, Renato Alberto Sinico, F. J. Van Der Woude, G. Gaskin
Publikováno v:
Journal of Immunological Methods, 196(1), 1-15. ELSEVIER SCIENCE BV
Anti-neutrophil cytoplasmic antibodies (ANCA) are diagnostic markers for systemic vasculitis. They are classically detected by an indirect immunofluorescence test using normal donor neutrophils as substrate. This assay lacks antigenic specificity and