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Nicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response

Autor: X R Mao, D M Kaufman, C M Crowder

Publikováno v: Cell Death & Disease

Gain-of-function mutations in the mouse nicotinamide mononucleotide adenylyltransferase type 1 (Nmnat1) produce two remarkable phenotypes: protection against traumatic axonal degeneration and reduced hypoxic brain injury. Despite intensive efforts, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6fa5b8a70b16543a4be2b0095deecb
https://doi.org/10.1038/cddis.2016.5

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Studies of Acetylcholine Receptor Subunit Gene Expression: Chromatin Structural Changes During Myogenesis

Autor: C M Crowder, J P Merlie

Publikováno v: Ciba Foundation Symposium 138-Plasticity of the Neuromuscular System

Myogenesis proceeds stepwise from pluripotential stem cell to differentiated myotube. The precise number of transitions that occur along the developmental pathway remains to be determined. We examined the myogenic pathway as modelled by mouse mesoder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d7c2e892d8861d67faed3fddddbe776
https://doi.org/10.1002/9780470513675.ch5

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A quantitative genetic approach towards volatile anesthetic mechanisms in C. elegans

Autor: B van Swinderen, C M Crowder, Alex Galifianakis

Publikováno v: Toxicology letters.

Quantitative genetics is the study of the heritability of continuous traits such as height or IQ. Quantitative trait loci (QTLs) represent the genes that are responsible for these quantitative traits. Sensitivity to the volatile anesthetic halothane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6746d30bea82503fe14438f4d773b25f
https://pubmed.ncbi.nlm.nih.gov/10049158

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Convection versus conduction cooling for induction of mild hypothermia during neurovascular procedures in adults

Autor: Rene Tempelhoff, Alexandre A. Todorov, Mary Ann Cheng, Ralph G. Dacey, C. M. Crowder, M. A. Theard

Publikováno v: Journal of neurosurgical anesthesiology. 9(3)

Hypothermia for cerebral protection is usually achieved by administration of intravenous fluids at room temperature, cooling ambient air, ice packs, and a temperature-adjustable circulating water mattress. We compared cooling by conduction by using a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7635093e7de9293bacb0ba0e4681a590
https://pubmed.ncbi.nlm.nih.gov/9239588

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