Zobrazeno 1 - 10
of 30
pro vyhledávání: '"C M Anjam Khan"'
Autor:
David M Bulmer, Lubna Kharraz, Andrew J Grant, Paul Dean, Fiona J E Morgan, Michail H Karavolos, Anne C Doble, Emma J McGhie, Vassilis Koronakis, Richard A Daniel, Pietro Mastroeni, C M Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://doaj.org/article/0e54051753e7417a9ab0ff1ecf95a74a
Autor:
Catherine F. Hatton, Rachel A. Botting, Maria Emilia Dueñas, Iram J. Haq, Bernard Verdon, Benjamin J. Thompson, Jarmila Stremenova Spegarova, Florian Gothe, Emily Stephenson, Aaron I. Gardner, Sandra Murphy, Jonathan Scott, James P. Garnett, Sean Carrie, Jason Powell, C. M. Anjam Khan, Lei Huang, Rafiqul Hussain, Jonathan Coxhead, Tracey Davey, A. John Simpson, Muzlifah Haniffa, Sophie Hambleton, Malcolm Brodlie, Chris Ward, Matthias Trost, Gary Reynolds, Christopher J. A. Duncan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The innate immune response in epithelial cells after SARS-CoV-2 infection is not fully understood. Here the authors use human air-liquid interface culture and show single cell transcription changes and delayed type I Interferon responses after SARS-C
Externí odkaz:
https://doaj.org/article/0c29a923bed447a88b3b4df91dd15100
Autor:
Michail H. Karavolos, Pietro Mastroeni, Lubna Kharraz, David M. Bulmer, Emma J. McGhie, Fiona J. E. Morgan, Paul Dean, Andrew J. Grant, Anne C. Doble, Vassilis Koronakis, Richard A. Daniel, C. M. Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
PLoS Pathogens
PLoS Pathogens
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c9c9b343cebceab62e914a8246c9d8
Publikováno v:
Molecular Microbiology. 87:455-465
The interactions between bacterial pathogens and their eukaryotic hosts are vital in determining the outcome of infections. Bacterial pathogens employ molecular sensors to detect and facilitate adaptation to changes in their niche. The sensing of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a54c2a408c58428b93778642a1bbbb6d
https://doi.org/10.1111/mmi.12110
https://doi.org/10.1111/mmi.12110
Publikováno v:
Scopus-Elsevier
The ability of bacterial pathogens to sense their immediate environment plays a significant role on their capacity to survive and cause disease. Salmonella enterica serovar typhi (S. typhi) is an exclusively human pathogen that causes typhoid fever.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddd652be15217d5ff4705f3dc74baae
https://doi.org/10.4161/viru.2.4.16810
https://doi.org/10.4161/viru.2.4.16810
Autor:
Heather Brookes, Luisa Sturiale, Teresa Ieranò, Rosa Lanzetta, F. Kate Gould, Paul A. Corris, Antonio Molinaro, Domenico Garozzo, C. M. Anjam Khan, Michelangelo Parrilli, Alba Silipo, Anthony De Soyza, Clare E. Bryant
Publikováno v:
Glycobiology (Oxf.) 18 (2008): 871–881.
info:cnr-pdr/source/autori:T.Ieranò, A.Silipo, L.Sturiale, D.Garozzo, H.Brookes, C.M.Anjam Khan, C.Bryant, F.K.Gould, P.A.Corris, R.Lanzetta, M.Parrilli, A.De Soyza, A.Molinaro/titolo:The structure and proinflammatory activity of the lipopolysaccharide from Burkholderia multivorans and the differences between clonal strains colonizing pre and posttransplanted lungs/doi:/rivista:Glycobiology (Oxf.)/anno:2008/pagina_da:871/pagina_a:881/intervallo_pagine:871–881/volume:18
info:cnr-pdr/source/autori:T.Ieranò, A.Silipo, L.Sturiale, D.Garozzo, H.Brookes, C.M.Anjam Khan, C.Bryant, F.K.Gould, P.A.Corris, R.Lanzetta, M.Parrilli, A.De Soyza, A.Molinaro/titolo:The structure and proinflammatory activity of the lipopolysaccharide from Burkholderia multivorans and the differences between clonal strains colonizing pre and posttransplanted lungs/doi:/rivista:Glycobiology (Oxf.)/anno:2008/pagina_da:871/pagina_a:881/intervallo_pagine:871–881/volume:18
The Burkholderia cepacia complex is a group of Gram-negative bacteria that are opportunistic pathogens for humans especially in cystic fibrosis patients. Lipopolysaccharide (LPS) molecules are potent virulence factors of Gram-negative bacteria organi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c913bccb7f180a64da8a2dc8c2c6aa7
https://doi.org/10.1093/glycob/cwn074
https://doi.org/10.1093/glycob/cwn074
Autor:
Ulrich Zähringer, C. M. Anjam Khan, Raquel Demarco De Hormaeche, Buko Lindner, Charles D. Ellis
Publikováno v:
Molecular Microbiology. 42:167-181
LPS is a fundamental constituent of the outer membrane of all Gram-negative bacteria, and the lipid A domain plays a central role in the induction of inflammatory responses. We identified genes of the Neisseria gonorrhoeae lipid A biosynthetic pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f45a641bf35451abf8765cf23e187fb3
https://doi.org/10.1046/j.1365-2958.2001.02619.x
https://doi.org/10.1046/j.1365-2958.2001.02619.x
Autor:
Fidel Zavala, Michail H. Karavolos, C E Hormaeche, Jeong Jin Lee, Duncan J. Maskell, David M. Bulmer, C. M. Anjam Khan, Shahid Khan, Nicola D. McKelvie, Raquel DeMarco
Publikováno v:
FEMS Immunology & Medical Microbiology. 52:237-246
Live Salmonella vaccines are limited in use by the inherent toxicity of the lipopolysaccharide. The waaN gene encodes a myristyl transferase required for the secondary acylation of lipid A in lipopolysaccharide. A waaN mutant exhibits reduced inducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7758d62e187a8a4d677e31c79bc88988
https://doi.org/10.1111/j.1574-695x.2007.00368.x
https://doi.org/10.1111/j.1574-695x.2007.00368.x
Autor:
Raquel Demarco Carlos E. Hormaeche, C. M. Anjam Khan, Wen-Tssann Liu, Jeong Jin Lee, David M. Bulmer, Abdelmounaaim Allaoui, Michail H. Karavolos
Publikováno v:
Microbial Pathogenesis. 42:2-10
Pathogenic bacteria employ a variety of mechanisms to resist a barrage of stresses they encounter during active growth in or outside the host as well as during growth stasis. An in silico screen of the Salmonella genome sequence revealed that Salmone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1486f3cdb9b045a03a81f49cda6eac
https://doi.org/10.1016/j.micpath.2006.09.002
https://doi.org/10.1016/j.micpath.2006.09.002
Autor:
Paul A. Corris, Anthony De Soyza, Charles D. Ellis, Raquel Demarco de Hormaeche, C. M. Anjam Khan
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 170:70-77
Organisms from the Burkholderia cepacia complex are important pathogens in cystic fibrosis and are associated with increased rates of sepsis and death. These organisms comprise nine closely related species known as genomovars. B. cenocepacia (genomov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41b190d9dacf79fa0f8ce30d07aada2
https://doi.org/10.1164/rccm.200304-592oc
https://doi.org/10.1164/rccm.200304-592oc