Zobrazeno 1 - 10
of 602
pro vyhledávání: '"C Møller"'
Autor:
Pauline Scholler, Damien Nevoltris, Dimitri de Bundel, Simon Bossi, David Moreno-Delgado, Xavier Rovira, Thor C. Møller, Driss El Moustaine, Michaël Mathieu, Emilie Blanc, Heather McLean, Elodie Dupuis, Gérard Mathis, Eric Trinquet, Hervé Daniel, Emmanuel Valjent, Daniel Baty, Patrick Chames, Philippe Rondard, Jean-Philippe Pin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
G protein-coupled receptors are considered promising therapeutic targets. Here, the authors have identified nanobodies, or single-domain llama antibodies, that specifically enhance agonist-induced activity of a type of G protein-coupled receptor, the
Externí odkaz:
https://doaj.org/article/816648732d614ed3bfb0746f18dd9438
Akademický článek
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Akademický článek
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Autor:
Anna J. M. Aabakke, Tanja G. Petersen, Karen Wøjdemann, Mette H. Ibsen, Fjola Jonsdottir, Elisabeth Rønneberg, Charlotte S. Andersen, Anne Hammer, Tine D. Clausen, Julie Milbak, Lars Burmester, Rikke Zethner, Birgitte Lindved, Annette Thorsen‐Meyer, Mohammed R. Khalil, Birgitte Henriksen, Lisbeth Jønsson, Lise L. T. Andersen, Kamilla K. Karlsen, Monica L. Pedersen, Gitte Hedermann, Marianne Vestgaard, Dorthe Thisted, Agnethe N. Fallesen, Josephine N. Johansson, Ditte C. Møller, Greta Dubietyte, Charlotte B. Andersson, Richard Farlie, Ane‐Kersti Skaarup Knudsen, Lea Hansen, Lone Hvidman, Anne N. Sørensen, Sidsel L. Rathcke, Katrine H. Rubin, Lone K. Petersen, Jan S. Jørgensen, Lone Krebs, Mette Bliddal
Publikováno v:
Aabakke, A J M, Petersen, T G, Wøjdemann, K, Ibsen, M H, Jonsdottir, F, Rønneberg, E, Andersen, C S, Hammer, A, Clausen, T D, Milbak, J, Burmester, L, Zethner, R, Lindved, B, Thorsen-Meyer, A, Khalil, M R, Henriksen, B, Jønsson, L, Andersen, L L T, Karlsen, K K, Pedersen, M L, Hedermann, G, Vestgaard, M, Thisted, D, Fallesen, A N, Johansson, J N, Møller, D C, Dubietyte, G, Andersson, C B, Farlie, R, Skaarup Knudsen, A-K, Hansen, L, Hvidman, L, Sørensen, A N, Rathcke, S L, Rubin, K H, Petersen, L K, Jørgensen, J S, Krebs, L & Bliddal, M 2023, ' Risk factors for and pregnancy outcomes after SARS-CoV-2 in pregnancy according to disease severity : A nationwide cohort study with validation of the SARS-CoV-2 diagnosis ', Acta Obstetricia et Gynecologica Scandinavica, vol. 102, no. 3, pp. 282–293 . https://doi.org/10.1111/aogs.14512
Aabakke, A J M, Petersen, T G, Wøjdemann, K, Ibsen, M H, Jonsdottir, F, Rønneberg, E, Andersen, C S, Hammer, A, Clausen, T D, Milbak, J, Burmester, L, Zethner, R, Lindved, B, Thorsen-Meyer, A, Khalil, M R, Henriksen, B, Jønsson, L, Andersen, L L T, Karlsen, K K, Pedersen, M L, Hedermann, G, Vestgaard, M, Thisted, D, Fallesen, A N, Johansson, J N, Møller, D C, Dubietyte, G, Andersson, C B, Farlie, R, Skaarup Knudsen, A-K, Hansen, L, Hvidman, L, Sørensen, A N, Rathcke, S L, Rubin, K H, Petersen, L K, Jørgensen, J S, Krebs, L & Bliddal, M 2023, ' Risk factors for and pregnancy outcomes after SARS-CoV-2 in pregnancy according to disease severity : A nationwide cohort study with validation of the SARS-CoV-2 diagnosis ', Acta Obstetricia et Gynecologica Scandinavica, vol. 102, no. 3, pp. 282-293 . https://doi.org/10.1111/aogs.14512
Aabakke, A J M, Petersen, T G, Wøjdemann, K, Ibsen, M H, Jonsdottir, F, Rønneberg, E, Andersen, C S, Hammer, A, Clausen, T D, Milbak, J, Burmester, L, Zethner, R, Lindved, B, Thorsen-Meyer, A, Khalil, M R, Henriksen, B, Jønsson, L, Andersen, L L T, Karlsen, K K, Pedersen, M L, Hedermann, G, Vestgaard, M, Thisted, D, Fallesen, A N, Johansson, J N, Møller, D C, Dubietyte, G, Andersson, C B, Farlie, R, Skaarup Knudsen, A K, Hansen, L, Hvidman, L, Sørensen, A N, Rathcke, S L, Rubin, K H, Petersen, L K, Jørgensen, J S, Krebs, L & Bliddal, M 2023, ' Risk factors for and pregnancy outcomes after SARS-CoV-2 in pregnancy according to disease severity : A nationwide cohort study with validation of the SARS-CoV-2 diagnosis ', Acta Obstetricia et Gynecologica Scandinavica, vol. 102, no. 3, pp. 282-293 . https://doi.org/10.1111/aogs.14512
Aabakke, A J M, Petersen, T G, Wøjdemann, K, Ibsen, M H, Jonsdottir, F, Rønneberg, E, Andersen, C S, Hammer, A, Clausen, T D, Milbak, J, Burmester, L, Zethner, R, Lindved, B, Thorsen-Meyer, A, Khalil, M R, Henriksen, B, Jønsson, L, Andersen, L L T, Karlsen, K K, Pedersen, M L, Hedermann, G, Vestgaard, M, Thisted, D, Fallesen, A N, Johansson, J N, Møller, D C, Dubietyte, G, Andersson, C B, Farlie, R, Skaarup Knudsen, A-K, Hansen, L, Hvidman, L, Sørensen, A N, Rathcke, S L, Rubin, K H, Petersen, L K, Jørgensen, J S, Krebs, L & Bliddal, M 2023, ' Risk factors for and pregnancy outcomes after SARS-CoV-2 in pregnancy according to disease severity : A nationwide cohort study with validation of the SARS-CoV-2 diagnosis ', Acta Obstetricia et Gynecologica Scandinavica, vol. 102, no. 3, pp. 282-293 . https://doi.org/10.1111/aogs.14512
Aabakke, A J M, Petersen, T G, Wøjdemann, K, Ibsen, M H, Jonsdottir, F, Rønneberg, E, Andersen, C S, Hammer, A, Clausen, T D, Milbak, J, Burmester, L, Zethner, R, Lindved, B, Thorsen-Meyer, A, Khalil, M R, Henriksen, B, Jønsson, L, Andersen, L L T, Karlsen, K K, Pedersen, M L, Hedermann, G, Vestgaard, M, Thisted, D, Fallesen, A N, Johansson, J N, Møller, D C, Dubietyte, G, Andersson, C B, Farlie, R, Skaarup Knudsen, A K, Hansen, L, Hvidman, L, Sørensen, A N, Rathcke, S L, Rubin, K H, Petersen, L K, Jørgensen, J S, Krebs, L & Bliddal, M 2023, ' Risk factors for and pregnancy outcomes after SARS-CoV-2 in pregnancy according to disease severity : A nationwide cohort study with validation of the SARS-CoV-2 diagnosis ', Acta Obstetricia et Gynecologica Scandinavica, vol. 102, no. 3, pp. 282-293 . https://doi.org/10.1111/aogs.14512
INTRODUCTION: We identified risk factors and outcomes associated with SARS-CoV-2 infection in pregnancy in a universally tested population according to disease severity and validated information on SARS-CoV-2 during pregnancy in national health regis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf6559ac233acfe3d2c74fa341d2a22
https://curis.ku.dk/ws/files/340003379/Acta_Obstet_Gynecol_Scand_2023_Aabakke_Risk_factors_for_and_pregnancy_outcomes_after_SARS_CoV_2_in_pregnancy.pdf
https://curis.ku.dk/ws/files/340003379/Acta_Obstet_Gynecol_Scand_2023_Aabakke_Risk_factors_for_and_pregnancy_outcomes_after_SARS_CoV_2_in_pregnancy.pdf
Autor:
David Moreno Delgado, Thor C Møller, Jeanne Ster, Jesús Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M Zwier, Julie Perroy, Thierry Durroux, Eric Trinquet, Laurent Prezeau, Philippe Rondard, Jean-Philippe Pin
Publikováno v:
eLife, Vol 6 (2017)
Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells
Externí odkaz:
https://doaj.org/article/45f8031aa1ce42f587b4ebe1846baae1
Akademický článek
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Publikováno v:
Moo, E V, Van Senten, J R, Bräuner-osborne, H & Møller, T C 2021, ' Arrestin-Dependent and-Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling ', Molecular Pharmacology, vol. 99, no. 4, pp. 242-255 . https://doi.org/10.1124/molpharm.120.000192
Molecular Pharmacology
Molecular Pharmacology
Agonist-induced endocytosis is a key regulatory mechanism for controlling the responsiveness of the cell by changing the density of cell surface receptors. In addition to the role of endocytosis in signal termination, endocytosed G protein-coupled re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaa541237585bec4578b1181c1dcbc8
https://doi.org/10.1124/molpharm.120.000192
https://doi.org/10.1124/molpharm.120.000192
Autor:
Sine P. Schiellerup, Gertrud Malene Hjortø, Mette M. Rosenkilde, Florent Xavier Smit, Olav Larsen, Bolette Hartmann, Thor C. Møller, C. Christiansen, Jens J. Holst, Wijnand J.C. van der Velden, Hans Bräuner-Osborne, Thomas M. Frimurer
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Biased ligands that selectively confer activity in one pathway over another are pharmacologically important because biased signaling may reduce on-target side effects and improve drug efficacy. Here, we describe an N-terminal modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1b2b60a588622bae14728766e1f217
https://doi.org/10.1021/acsptsci.0c00193
https://doi.org/10.1021/acsptsci.0c00193
Autor:
Hans Bräuner-Osborne, Karen J. Gregory, Thor C. Møller, Line Vedel, Angela Arsova, Simon R. Foster, Jakob Lerche Hansen
Publikováno v:
Mol Pharmacol
Molecular Pharmacology
Molecular Pharmacology
Negative allosteric modulation of the metabotropic glutamate 5 (mGlu(5)) receptor has emerged as a potential strategy for the treatment of neurologic disorders. Despite the success in preclinical studies, many mGlu(5) negative allosteric modulators (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e3a856e1919599f13a55388bfec28c
https://doi.org/10.1124/mol.119.119032
https://doi.org/10.1124/mol.119.119032
Publikováno v:
The Journal of biological chemistry. 298(10)
The internalization of G protein-coupled receptors (GPCRs) can be regulated by PKC. However, most tools available to study the contribution of PKC isozymes have considerable limitations, including a lack of selectivity. In this study, we generated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37c6fabe3005ac52426425b58f23519a
https://pubmed.ncbi.nlm.nih.gov/36087841
https://pubmed.ncbi.nlm.nih.gov/36087841