Zobrazeno 1 - 10
of 173
pro vyhledávání: '"C M, Svahn"'
Publikováno v:
Journal of Biological Chemistry. 269:32279-32285
The fibroblast growth factors (FGFs) act through high affinity tyrosine kinase receptors and, in addition, interact with lower affinity receptors that represent cell- or matrix-associated heparan sulfate proteoglycans. These lower affinity receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e26d435fc6ac6b6aa57b3320b8bd1c
https://doi.org/10.1016/s0021-9258(18)31632-6
https://doi.org/10.1016/s0021-9258(18)31632-6
Publikováno v:
Journal of Biological Chemistry. 268:7685-7691
Vascular endothelial growth factor (VEGF) is a mitogen for cultured endothelial cells, and a potent angiogenic factor in vivo. Incubation of 125I-VEGF with human or bovine serum led to the formation of 125I-VEGF containing complexes that had a molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2881f61ba57c61f2ac39d1f4ad9c92ee
https://doi.org/10.1016/s0021-9258(18)53011-8
https://doi.org/10.1016/s0021-9258(18)53011-8
Autor:
W, Völker, A, Böhm, A, Schmidt, C M, Svahn, A K, Gellerbring, C, Mattsson, S, Ekvärn, H, Robenek, E, Buddecke
Publikováno v:
Arzneimittel-Forschung. 45(5)
Low-anticoagulant heparin (LA-heparin) obtained by affinity chromatography on antithrombin III Sepharose inhibits the proliferation of cultured arterial smooth muscle cells in an in vitro bioassay system as effectively as standard heparin. A growth i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e15d8ef4f4f04063f18f6475d5ffd16e
https://pubmed.ncbi.nlm.nih.gov/7612053
https://pubmed.ncbi.nlm.nih.gov/7612053
Autor:
M, Bitan, M, Mohsen, E, Levi, M R, Wygoda, H Q, Miao, O, Lider, C M, Svahn, H P, Ekre, R, Ishai-Michaeli, R, Bar-Shavit
Publikováno v:
Israel journal of medical sciences. 31(2-3)
Heparanase activity correlates with metastatic potentials of lymphoma, melanoma and mammary adenocarcinoma cell lines. We investigated the ability of various modified species of heparin and size homogeneous oligosaccharides derived from depolymerized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57b64e27d724292413fede65a90c0d01
https://pubmed.ncbi.nlm.nih.gov/7744578
https://pubmed.ncbi.nlm.nih.gov/7744578
Publikováno v:
Biochemical and biophysical research communications. 203(2)
The binding of the 165 amino-acid form of vascular endothelial growth factor (VEGF165) to the VEGF receptors of vascular endothelial cells was potentiated by heparin and heparan-sulfate, but not by other glycosaminoglycans. Heparin fragments of 16-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6721a5bd23268a865e4ad8573c766c
https://pubmed.ncbi.nlm.nih.gov/7522446
https://pubmed.ncbi.nlm.nih.gov/7522446
Autor:
I, Vlodavsky, M, Mohsen, O, Lider, C M, Svahn, H P, Ekre, M, Vigoda, R, Ishai-Michaeli, T, Peretz
Publikováno v:
Invasionmetastasis. 14(1-6)
Heparanase activity correlates with the metastatic potential of lymphoma, melanoma and mammary adenocarcinoma cell lines. We investigated the ability of various modified species of heparin and size-homogeneous oligosaccharides derived from depolymeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7bb8568de2b6c9735eaf3d2780fff12
https://pubmed.ncbi.nlm.nih.gov/7657522
https://pubmed.ncbi.nlm.nih.gov/7657522
Autor:
Israel Vlodavsky, C. M. Svahn, R. Catane, R. Bar-Shavit, R. Ishai-Michaeli, Hans-Peter T. Ekre, M. Mohsen
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489924469
We have characterized the importance of size, sulfation and anticoagulant activity of heparin in: i) release of basic fibroblast growth factor (bFGF) from the subendothelial extracellular matrix (ECM), and ii) inhibition of heparanase (endo-β-D-gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::520f88dcbcb53c8e2fd301e993f84513
https://doi.org/10.1007/978-1-4899-2444-5_31
https://doi.org/10.1007/978-1-4899-2444-5_31
Publikováno v:
Advances in experimental medicine and biology. 313
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a786371672ef37d4cdaaab4293571c7
https://pubmed.ncbi.nlm.nih.gov/1279951
https://pubmed.ncbi.nlm.nih.gov/1279951
Autor:
Malcolm R. Smyth, S. Sprake, Jan-Erik Berg, Anne-Marie Pilotti, J. Barrett, C. M. Svahn, N. Å. Jönsson
Publikováno v:
Acta Chemica Scandinavica. :137-140
Aus dem Ethylester der Saure wird durch kontrollierte Hydrolyse in 6N HCl die rac. Saure (I) in 71% Ausb. erhalten.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c434811cbcd071a7124186ad9b0e99
https://doi.org/10.3891/acta.chem.scand.32b-0137
https://doi.org/10.3891/acta.chem.scand.32b-0137
Publikováno v:
Journal of Medicinal Chemistry. 29:448-453
Derivatives of the antifibrinolytic drug tranexamic acid [trans-4-(aminomethyl)cyclohexanecarboxylic acid] containing one or two tranexamic acid moieties were synthesized. Most of the derivatives have good stability in acidic and neutral solutions bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf7ed85c1faa9b0261e2ff163148b99
https://doi.org/10.1021/jm00154a004
https://doi.org/10.1021/jm00154a004