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Induction of Human Factor VIII Inhibitors in Rats by Immunization with Human Recombinant Factor VIII: a Small Animal Model for Humans with High Responder Inhibitor Phenotype

Autor: Michael A. Jarvis, C. L. Ziaja, C. M. Suzuki, D. J. DePianto, Charles F. Abildgaard, Jennifer Brown, Jerry S. Powell, K. W. Jolly, H. M. Reisner, Janet Harrison, L. G. Levin

Publikováno v: Scopus-Elsevier

SummaryHemophilia A is a clotting disorder that is due to reduced or absent coagulation factor VIII (FVIII) activity. In approximately 25% of people with severe hemophilia A, standard treatment with intravenous plasma-derived or recombinant FVIII (rF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00005f3138fb8b073f3d791dbec67081
https://doi.org/10.1055/s-0038-1650268

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Induction of human factor VIII inhibitors in rats by immunization with human recombinant factor VIII: a small animal model for humans with high responder inhibitor phenotype

Autor: M A, Jarvis, L G, Levin, J A, Harrison, D J, DePianto, C M, Suzuki, C L, Ziaja, J E, Brown, K W, Jolly, H M, Reisner, C F, Abildgaard, J S, Powell

Publikováno v: Thrombosis and haemostasis. 75(2)

Hemophilia A is a clotting disorder that is due to reduced or absent coagulation factor VIII (FVIII) activity. In approximately 25% of people with severe hemophilia A, standard treatment with intravenous plasma-derived or recombinant FVIII (rFVIII) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c9b9e674951e0f7f09f479ca6d3f02db
https://pubmed.ncbi.nlm.nih.gov/8815584

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