Zobrazeno 1 - 10
of 59
pro vyhledávání: '"C M, Snapper"'
Autor:
Young J. Juhn, Hirohito Kita, Govindarajan Rajagopalan, Y. H. Sheen, Chung-Il Wi, Puja J. Umaretiya, C. M. Snapper
Publikováno v:
HLA. 88:25-34
Asthma is independently associated with HLA-DR3 and increased risks of pneumococcal diseases. We aimed to determine whether HLA-DR polymorphism (HLA-DRB1*03), sensitization to house dust mite (HDM), or their interaction affects humoral immune respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfa0be5dca180bd4c28cee67b1fcf8ff
https://doi.org/10.1111/tan.12851
https://doi.org/10.1111/tan.12851
Publikováno v:
HLA. 88(1-2)
Asthma is independently associated with HLA-DR3 and increased risks of pneumococcal diseases. We aimed to determine whether HLA-DR polymorphism (HLA-DRB1*03), sensitization to house dust mite (HDM), or their interaction affects humoral immune respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d067cad291325c8af3f5ba41169e1b65
https://pubmed.ncbi.nlm.nih.gov/27506953
https://pubmed.ncbi.nlm.nih.gov/27506953
Publikováno v:
The Journal of Immunology. 159:2559-2562
DNA-dependent protein kinase, the catalytic subunit associated with the Ku heterodimer (Ku70/Ku86), has been implicated in switch recombination. Therefore, we tested whether certain stimuli known to promote switch recombination may act in part by ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43284c6db71578a6bd658ac6ea1bb78f
https://doi.org/10.4049/jimmunol.159.6.2559
https://doi.org/10.4049/jimmunol.159.6.2559
Autor:
C M Snapper, J J Mond
Publikováno v:
The Journal of Immunology. 157:2229-2233
We provide a model for induction of T cell-independent, polysaccharide-specific Ig secretion in response to bacterial challenge. Two predominant pathways are defined that require the concerted action of multivalent membrane Ig cross-linking by the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed566735862571a2184368af063fce93
https://doi.org/10.4049/jimmunol.157.6.2229
https://doi.org/10.4049/jimmunol.157.6.2229
Publikováno v:
The Journal of Immunology. 156:2828-2839
Targeted disruption of the p50 subunit of NF-kappa B resulted in isotype class switch defects resembling those observed in mice in which the downstream IgH enhancer 3'alpha E(hs1,2) was deleted. We postulated that kappa B binding proteins may regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7108acb473dd834348b0a4cf59ed2599
https://doi.org/10.4049/jimmunol.156.8.2828
https://doi.org/10.4049/jimmunol.156.8.2828
Publikováno v:
The Journal of Immunology. 156:183-191
To better understand the role of NF-kappaB in normal B cell physiology, we used a purified population of resting B cells from p50/NF-kappa B knockout (p50-/-) mice to determine their ability to proliferate, secrete Ig, express germ-line CHRNA, and un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fa058e7752201ad11b267a9c65efa3d
https://doi.org/10.4049/jimmunol.156.1.183
https://doi.org/10.4049/jimmunol.156.1.183
Publikováno v:
The Journal of Immunology. 154:3156-3161
The parameters necessary for induction of high-rate IgA class switching are unknown. Thus, although TGF-beta is switch factor for the IgA class, the percentage of membrane (m)IgA+ cells generated in vitro in response to TGF-beta and various individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85533f794abb70bba9c3907efeb40604
https://doi.org/10.4049/jimmunol.154.7.3156
https://doi.org/10.4049/jimmunol.154.7.3156
Publikováno v:
The Journal of Immunology. 154:1177-1187
A number of previous studies have suggested that cross-linkage of the B cell Ag receptor may be critical for induction of humoral immune responses to T cell-dependent (TD) Ags in vivo. Previous work also indicated a critical role, in these responses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e13e1638becfc37a9da27191eca507e
https://doi.org/10.4049/jimmunol.154.3.1177
https://doi.org/10.4049/jimmunol.154.3.1177
Publikováno v:
The Journal of Immunology. 154:1223-1231
Cytokines are believed to regulate Ig class switching, in part, through selective modulation of germ-line constant heavy (CH) gene transcription. B cell activators such as LPS or activated T cell membranes also influence germ-line CH RNA expression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d6c6916b2894e9a8c4828bc7508d74b
https://doi.org/10.4049/jimmunol.154.3.1223
https://doi.org/10.4049/jimmunol.154.3.1223
Publikováno v:
The Journal of Immunology. 153:1536-1543
Administration of IL-1 and stem cell factor (SCF) to mice 18 h before lethal 60Co whole-body irradiation resulted in synergistic radioprotection, as evidenced by increased numbers of mice surviving 1,200 to 1,300 cGy doses of radiation and the recove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c80ff32fcd785f91b62c81d94d373c
https://doi.org/10.4049/jimmunol.153.4.1536
https://doi.org/10.4049/jimmunol.153.4.1536