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pro vyhledávání: '"C M, Sheckler"'
Autor:
W J, Pan, H, Hsu, W A, Rees, S P, Lear, F, Lee, I N, Foltz, P, Rathanaswami, K, Manchulenko, B M, Chan, M, Zhang, X Z, Xia, S K, Patel, P J, Prince, D R, Doherty, C M, Sheckler, K O, Reynhardt, C D, Krill, B J, Harder, J A, Wisler, J L, Brandvig, J L, Lynch, A A, Anderson, L C, Wienkers, D C, Borie
Publikováno v:
British journal of pharmacology. 169(1)
AMG 181 is a human anti-α4 β7 antibody currently in phase 1 and 2 trials in subjects with inflammatory bowel diseases. AMG 181 specifically targets the α4 β7 integrin heterodimer, blocking its interaction with mucosal addressin cell adhesion mole