Zobrazeno 1 - 6
of 6
pro vyhledávání: '"C M, Segeren"'
Autor:
B. Lowenberg, R. Neuwirtova, C. M. Segeren, H. Dohner, H.M Lokhorst, R. Willemze, P. Sonneveld, Stefan Suciu, M. Beksac, H. Gerhartz, P. Weijermans, J van der Lelie, G. Solbu
Publikováno v:
British Journal of Haematology. 115:895-902
Patients with multiple myeloma (MM) refractory to alkylating agents frequently express P-glycoprotein (Pgp), which is associated with the multidrug resistance (MDR) phenotype. We have conducted a randomized phase II/III study of the MDR reversal agen
Autor:
M, van Agthoven, C M, Segeren, I, Buijt, C A, Uyl-de Groot, B, van der Holt, H M, Lokhorst, P, Sonneveld
Publikováno v:
European journal of cancer (Oxford, England : 1990). 40(8)
A prospective randomised phase III study in patientsor =65 years old with previously untreated multiple myeloma (MM), intensive chemotherapy followed by myeloablative chemotherapy and autologous stem-cell rescue was compared with intensive chemothera
Autor:
P, Sonneveld, S, Suciu, P, Weijermans, M, Beksac, R, Neuwirtova, G, Solbu, H, Lokhorst, J, van der Lelie, H, Dohner, H, Gerhartz, C M, Segeren, R, Willemze, B, Lowenberg
Publikováno v:
British journal of haematology. 115(4)
Patients with multiple myeloma (MM) refractory to alkylating agents frequently express P-glycoprotein (Pgp), which is associated with the multidrug resistance (MDR) phenotype. We have conducted a randomized phase II/III study of the MDR reversal agen
Autor:
P, de Lange, C M, Segeren, J W, Koper, E, Wiemer, P, Sonneveld, A O, Brinkmann, A, White, I J, Brogan, F H, de Jong, S W, Lamberts
Publikováno v:
Cancer research. 61(10)
Glucocorticoids play an important role in the treatment of a number of hematological malignancies, such as multiple myeloma. The effects of glucocorticoids are mediated through the glucocorticoid receptor alpha, the abundance of which can be modulate
Autor:
C M, Segeren, P, Sonneveld, B, van der Holt, J W, Baars, D H, Biesma, J J, Cornellissen, A J, Croockewit, A W, Dekker, W E, Fibbe, B, Löwenberg, M, van Marwijk Kooy, M H, van Oers, D J, Richel, H C, Schouten, E, Vellenga, G E, Verhoef, P W, Wijermans, S, Wittebol, H M, Lokhorst
Publikováno v:
British journal of haematology. 105(1)
We examined the feasibility of achieving a rapid response in patients with previously untreated multiple myeloma by administering vincristine 0.4 mg and doxorubicin 9 mg/m2 as a rapid intravenous infusion for 4 d together with intermittent high-dose
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 142(28)
There are a number of studies dealing with intensive chemotherapy and stem cell transplantation in multiple myeloma. As to autologous transplantation best results have been obtained with younger patients (below 60 years) who had responsive disease an