Zobrazeno 1 - 10
of 19
pro vyhledávání: '"C M, Rudin"'
Autor:
P, Selenica, A, Marra, N J, Choudhury, A, Gazzo, C J, Falcon, J, Patel, X, Pei, Y, Zhu, C K Y, Ng, M, Curry, G, Heller, Y-K, Zhang, M F, Berger, M, Ladanyi, C M, Rudin, S, Chandarlapaty, C M, Lovly, J S, Reis-Filho, H A, Yu
Studies of targeted therapy resistance in lung cancer have primarily focused on single-gene alterations. Based on prior work implicating apolipoprotein b mRNA-editing enzyme, catalytic polypeptide-like (APOBEC) mutagenesis in histological transformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489362d8fe1f3452c071fd88fa3f3ebb
Publikováno v:
The Journal of Immunology. 147:2354-2358
A strong transcriptional enhancer was identified for the human lambda L chain Ig gene complex. Enhancer activity was measured by activation of the chloramphenicol acetyl transferase (CAT) gene in a transient assay using both mouse and human B lymphoi
Publikováno v:
The Journal of Immunology. 144:4857-4862
A cDNA clone was isolated from a mouse pre-B cell line, the sequence of which has a very high homology with rat and human thymosin beta 4 genes. However, the mouse clone has an insertion of 98 bp relative to the published rat and human sequences upst
Publikováno v:
Oncologic Therapies ISBN: 9783642628184
This chapter details the epidemiology, pathophysiology, clinical presentation, diagnostic approaches, and treatment modalities of several of the most common oncologic emergencies. Because of the systemic nature of cancer, these emergencies often affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c49813c13776ab4f480a2d5ebfed045
https://doi.org/10.1007/978-3-642-55780-4_7
https://doi.org/10.1007/978-3-642-55780-4_7
Autor:
E E, Cohen, C M, Rudin
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 2(12)
ONYX-015 (CI-1042), an adenovirus modified selectively to replicate in and kill cells that harbor p53 mutations, is under development by Onyx Pharmaceuticals for the potential treatment of various solid tumors, including head and neck, gastrointestin
Autor:
C M, Rudin, J, Holmlund, G F, Fleming, S, Mani, W M, Stadler, P, Schumm, B P, Monia, J F, Johnston, R, Geary, R Z, Yu, T J, Kwoh, F A, Dorr, M J, Ratain
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(5)
Raf-1 is a serine/threonine kinase that functions as a critical effector of Ras-mediated signal transduction via the mitogen-activated protein kinase pathway. Constitutive activation of this pathway directly contributes to malignant transformation in
Autor:
C M, Rudin, C B, Thompson
Publikováno v:
Genes, chromosomescancer. 30(1)
Short interspersed elements (SINEs), typified by the human Alu repeat, are RNA polymerase III (pol III)-transcribed sequences that replicate within the genome through an RNA intermediate. Replication of SINEs has been extensive in mammalian evolution
Autor:
C M, Carthy, D J, Granville, H, Jiang, J G, Levy, C M, Rudin, C B, Thompson, B M, McManus, D W, Hunt
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 79(8)
Certain nonmetallic porphyrins have potent antitumor activity upon visible light irradiation. Treatment of HeLa cells with nanomolar amounts of the photochemo therapeutic agent verteporfin and red light mobilized caspases 2, 3, 6, 7, 8, and 9, caused
Publikováno v:
Cancer. 85(1)
Inhibition of apoptosis, or programmed cell death, may be critical both in the development of cancer and in determining response to therapy. The authors examined the expression of two related apoptotic inhibitors, Bcl-2 and Bcl-xL, in pretreatment bi
Autor:
C. M. Rudin, P. R. Helft
Publikováno v:
Oncologic Therapies ISBN: 9783540781080
Oncologic Therapies
Oncologic Therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd365ae326207a6b148017a43c6c5a4
https://doi.org/10.1007/978-3-642-97988-0_10
https://doi.org/10.1007/978-3-642-97988-0_10