Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C M, Kielty"'
Publikováno v:
Journal of Cell Science. 112:4163-4171
The molecular mechanisms of fibrillin assembly into microfibrils are poorly understood. In this study, we investigated human fibrillin-1 carboxy-terminal processing and assembly using a recombinant approach. Processing of carboxy-terminal fibrillin-1
Publikováno v:
Journal of Experimental Biology. 202:3011-3020
The zonular filaments from the eyes of cows are rich in microfibrils containing fibrillin. Tensile tests, stress-relaxation tests and X-ray diffraction studies were used to study the relationship between the mechanical behaviour of zonular filaments
Autor:
C A Shuttleworth, C M Kielty
Publikováno v:
Microscopy Research and Technique. 38:413-427
Connective tissue microfibrils are key structural elements of the dermal matrix which play major roles in establishing and maintaining the structural and mechanical integrity of this complex tissue. Type VI collagen microfibrils form extensive microf
Autor:
Olivier D. Christophe, Nadine Ajzenberg, C M Kielty, Dominique Meyer, Dominique Baruch, Cécile V. Denis
Publikováno v:
Europe PubMed Central
We have recently shown that von Willebrand factor (vWF) binds to endothelial and fibroblastic extracellular matrixes (ECM) in a dose-dependent, specific, and saturable way. To localize the domain on the vWF subunit responsible for this interaction, p
Publikováno v:
Journal of muscle research and cell motility. 23(5-6)
Fibrillin-rich microfibrils are evolutionarily ancient macromolecular assemblies of the extracellular matrix. They have unique extensible properties that endow vascular and other tissues with long-range elasticity. Microfibril extensibility supports
Publikováno v:
Mechanics of Elastic Biomolecules ISBN: 9789401039710
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e509207dc58f5e008c2dad2a5d3acf3d
https://doi.org/10.1007/978-94-010-0147-2_17
https://doi.org/10.1007/978-94-010-0147-2_17
Publikováno v:
Arthritis and rheumatism. 44(8)
To determine if there are abnormalities in fibrillin 1-containing microfibrils in the extracellular matrix (ECM) of primary dermal fibroblasts explanted from patients with systemic sclerosis (SSc).Explanted fibroblasts from unaffected skin of 12 SSc
Publikováno v:
Biochemical Society transactions. 26(1)
Autor:
J L, Ashworth, G, Murphy, M J, Rock, M J, Sherratt, S D, Shapiro, C A, Shuttleworth, C M, Kielty
Publikováno v:
The Biochemical journal. 340
Fibrillin is the principal structural component of the 10-12 nm diameter elastic microfibrils of the extracellular matrix. We have previously shown that both fibrillin molecules and assembled microfibrils are susceptible to degradation by serine prot