Zobrazeno 1 - 10
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pro vyhledávání: '"C M, Fleischmann"'
Autor:
C M, Fleischmann, W R, Fleischmann
Publikováno v:
Journal of biological regulators and homeostatic agents. 9(4)
Resistance to the in vitro antiproliferative effects of INF-alpha rapidly develops in mouse B16 melanoma cells that are maintained in vitro in IFN-alpha (B16 alpha res cells). B16 alpha res cells, however, are significantly more sensitive to the anti
Autor:
W R, Fleischmann, C M, Fleischmann
Publikováno v:
Journal of biological regulators and homeostatic agents. 8(4)
Heat-induced total body hyperthermia has been shown to synergistically enhance the in vivo antitumor effects of MuIFN-gamma directed against B16 melanoma in mice. This observation was made with an 8-hour exposure to hyperthermia that was administered
Publikováno v:
Journal of biological regulators and homeostatic agents. 7(2)
Non-genetic resistance to the antiproliferative effects of interferon-alpha (IFN-alpha) develops in murine and human melanoma cells within 2-4 days of exposure of the cells to IFN-alpha. Simultaneous treatment of murine B16 melanoma cells with MuIFN-
Autor:
C M, Fleischmann, W R, Fleischmann
Publikováno v:
Journal of biological regulators and homeostatic agents. 5(1)
Mouse B16 melanoma cells have been shown to rapidly develop resistance to the antiproliferative effects of MuIFN-alpha or MuIFN-beta when exposed to these interferons. In cloning studies, the maximal antiproliferative effects of MuIFN-alpha were seen
Publikováno v:
Cancer research. 46(1)
Fever is frequently an important side effect of interferon (IFN) therapy. Studies have shown that culturing interferon-treated cells at elevated temperature heightens the antiproliferative activity of IFN-alpha and IFN-beta. Since IFN-gamma has also
Autor:
C M, Fleischmann, W R, Fleischmann
Publikováno v:
Journal of biological regulators and homeostatic agents. 2(3)
The relative enhancing effects of hyperthermia on the three types of interferon were evaluated in cloning studies for three human cell lines: G-361 malignant melanoma cells, WISH ammion cells, and AGS stomach adenocarcinoma cells. Hyperthermia enhanc
Publikováno v:
Cancer research. 46(4 Pt 1)
Previous studies have evaluated the effects of hyperthermia on the antiproliferative activity of interferon. The activities of all three types of interferon have been shown to be synergistically enhanced by hyperthermic conditions. Further, the antip
Autor:
C M, Fleischmann, W R, Fleischmann
Publikováno v:
Journal of biological regulators and homeostatic agents. 2(4)
Interferons have been recognized to have potent in vitro antiproliferative activities in mouse and human systems. To further investigate the kinetics of development of interferons' antiproliferative activities, mouse B-16 melanoma cells were treated
Publikováno v:
Journal of biological response modifiers. 3(4)
Combination treatment with interferon (IFN)-gamma and either IFN-alpha or IFN-beta synergistically enhances (potentiates) the anticellular effects of the IFNs. IFNs have been shown to have anticellular activity against normal as well as malignant cel
Publikováno v:
Journal of biological response modifiers. 3(6)
The interaction of the interferons (IFNs) that cooperate to potentiate the antiviral action of IFN was studied. Serial dilutions of MuIFN-gamma and MuIFN-alpha/beta were employed separately and in combination to block virus replication in one-step, v