Zobrazeno 1 - 10
of 23
pro vyhledávání: '"C M, Chase"'
Autor:
Paul S. Russell, Alessandro Alessandrini, Evan A. Farkash, Tsutomu Hirohashi, R. Neal Smith, Robert B. Colvin, C. M. Chase, Takurin Akiyoshi, Joren C. Madsen
Publikováno v:
Human Immunology. 73:1226-1232
Despite extensive research on T cells and potent immunosuppressive regimens that target cellular mediated rejection, few regimens have been proved to be effective on antibody-mediated rejection (AMR), particularly in the chronic setting. C4d depositi
Autor:
Joren C. Madsen, Alessandro Alessandrini, Paul S. Russell, C. M. Chase, Tsutomu Hirohashi, Robert B. Colvin, P. Della Pelle, Divya P Sebastian
Publikováno v:
American Journal of Transplantation. 12:313-321
Chronic allograft vasculopathy (CAV) in murine heart allografts can be elicited by adoptive transfer of donor specific antibody (DSA) to class I MHC antigens and is independent of complement. Here we address the mechanism by which DSA causes CAV. B6.
Autor:
C. M. Chase, Joren C. Madsen, Tsutomu Hirohashi, Shuichiro Uehara, Paul S. Russell, Robert B. Colvin, P. DellaPelle
Publikováno v:
American Journal of Transplantation. 10:510-517
Complement fixation, as evidenced by C4d in the microvasculature, is a widely accepted criterion of antibody-mediated rejection. Complement fixation has been shown to be essential in acute antibody-mediated rejection, but its role in chronic rejectio
Autor:
C. M. Chase, Joren C. Madsen, Lynn D. Cornell, William H. Kitchens, Paul S. Russell, Robert B. Colvin, Shuichiro Uehara
Publikováno v:
American Journal of Transplantation. 7:2675-2682
Cardiac allograft vasculopathy (CAV) is a major source of late posttransplant mortality. Although numerous cell types are implicated in the pathogenesis of CAV, it is unclear which cells actually induce the vascular damage that results in intimal pro
Autor:
C. M. Chase, Michael N. Starnbach, Irina B. Mazo, Annaiah Cariappa, Paul S. Russell, Guiying Cheng, Roberto Bonasio, Cornelia Halin, Pandelakis A. Koni, Shiv Pillai, Wolfgang Weninger, Lois L. Cavanagh, Adrianus W. M. van der Velden, Ulrich H. von Andrian
Publikováno v:
Nature Immunology. 6:1029-1037
Dendritic cells (DCs) carry antigen from peripheral tissues via lymphatics to lymph nodes. We report here that differentiated DCs can also travel from the periphery into the blood. Circulating DCs migrated to the spleen, liver and lung but not lymph
Autor:
Robert B. Colvin, Dorothy Ndishabandi, C. M. Raczek, Paul S. Russell, K. Shinoda, C. M. Chase, Takurin Akiyoshi, Joren C. Madsen, Divya P Sebastian, Alessandro Alessandrini, P. Della Pelle, Evan A. Farkash
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14(10)
The relative contribution of central and peripheral mechanisms to the generation and maintenance of allograft tolerance is of considerable interest. Here, we present new evidence that regulatory T cells (Foxp3(+) ) maintain skin and heart allograft t
Autor:
Robert B. Colvin, John Iacomini, Jennifer L. Bracy, C. M. Chase, Shamila Mauiyyedi, Paul S. Russell
Publikováno v:
Gene Therapy. 8:1738-1744
In order for xenotransplantation to become a clinical reality, and fulfill its promise of overcoming shortages of human organs and tissues, rejection mediated by the host's immune system must first be overcome. In primates, preformed natural antibodi
Publikováno v:
The Journal of Immunology. 152:5135-5141
Obstructive lesions in arterial vessels of transplanted organs constitute an important factor in the late failure of these organs, especially for the heart. The absence of obstructive lesions in syngeneic donor-recipient combinations, suggests that t
Autor:
Janet M. Loring, C M Chase, Hugh Auchincloss, Maarten Zijlstra, Rudolf Jaenisch, Paul S. Russell
Publikováno v:
The Journal of Experimental Medicine
Mice homozygous for a beta 2-microglobulin (beta 2-m) gene disruption lack beta 2-m protein and are deficient for functional major histocompatibility complex class I (MHC-I) molecules. The mutant mice have normal numbers of CD4+8- T helper cells, but
Autor:
Tanaka K, C. M. Chase, Toshiro Ito, Richard O. Hynes, A. Lacy-Hulbert, Rex Neal Smith, Paul S. Russell, Mollie Jurewicz, Mohamed H. Sayegh, Paolo Fiorina, Takuya Ueno, Atsushi Izawa, Hugh Auchincloss, Reza Abdi
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7(5)
Integrin alpha v beta 3 is important for cell survival, signaling and migration, particularly during angiogenesis and tumorigenesis, where it has been proposed as a therapeutic target. alpha v beta 3 is up-regulated following transplantation and beta