Zobrazeno 1 - 10
of 13
pro vyhledávání: '"C M, Brophy"'
Autor:
Howard Rasmussen, C. M. Bergh, James R. Goldenring, Thomas M. Lincoln, C. M. Brophy, D. T. Dransfield
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 268:H202-H212
Activation of either the adenylate cyclase pathway with forskolin or the guanylate cyclase pathway with sodium nitroprusside fails to induce active relaxation of serotonin-precontracted human umbilical artery smooth muscle (HUASM) but causes active r
Publikováno v:
International journal of surgical investigation. 1(4)
Thrombin contributes to hemostasis by activating platelets, the formation of fibrin, and contraction of the injured vessel. These effects are mediated through the proteolytic activity of thrombin. We hypothesized that thrombin may have a role in vaso
Cyclosporine, but not FK506, selectively induces renal and coronary artery smooth muscle contraction
Publikováno v:
Surgery. 123(4)
Cyclosporine immunosuppression for organ transplantation is associated with hypertension and nephrotoxicity. Because the effects of cyclosporine as an immunosuppressant are mediated by the effect of cyclosporine as a phosphatase inhibitor, and phosph
Publikováno v:
Biology of reproduction. 57(6)
Human umbilical artery smooth muscle is uniquely refractory to cyclic nucleotide-dependent vasorelaxation. Small heat shock proteins (HSPs) have been implicated as contractile regulatory proteins. Thus, we hypothesized that alterations in the phospho
Publikováno v:
Journal of vascular surgery. 18(2)
The tissue inhibitors of metalloproteinases (TIMPs) are major inhibitors of several enzymes that are destructive to connective tissue, and TIMP-1 has been reported to be deficient in the wall of abdominal aortic aneurysms. This deficiency could repre
Autor:
C M, Brophy
Publikováno v:
Current opinion in general surgery.
Among the vascular disorders of the small intestine, two major categories are mesenteric ischemia and occult gastrointestinal bleeding secondary to a mucosal or muscular lesion. Mesenteric ischemia remains a clinical entity with a high mortality. Rec
Autor:
C J, Kwolek, F B, Pomposelli, G A, Tannenbaum, C M, Brophy, G W, Gibbons, D R, Campbell, D V, Freeman, A, Miller, F W, LoGerfo
Publikováno v:
Journal of vascular surgery. 15(2)
This study was performed to evaluate the results of peripheral vascular reconstruction for arterial occlusive disease in patients with juvenile-onset diabetes mellitus. The results of 67 bypass procedures performed on 60 patients with juvenile-onset
Publikováno v:
Journal of vascular surgery. 13(6)
Vascular grafts in canines exhibit similar healing patterns to humans in that the graft surface forms a pseudointima over time but endothelializes only near the anastomotic sites. Thus the pseudointima at the midportion of the graft may represent a n
Autor:
A, Miller, P A, Stonebridge, A I, Tsoukas, C J, Kwolek, C M, Brophy, G W, Gibbons, D V, Freeman, F B, Pomposelli, D R, Campbell, F W, LoGerfo
Publikováno v:
Journal of vascular surgery. 13(6)
Despite a large experience with "blind" retrograde valvulotomy in in situ vein bypass grafting, the incidence of residual competent valves remains high, and valvulotome-induced injury is common. In this study we describe a new valvulotome and techniq
Publikováno v:
ASAIO transactions. 36(3)
This study shows that prosthetic arterial grafts stimulate platelets for as long as 1 year after implantation in a canine model. Carotid-to-distal aorta Dacron (DuPont, Wilmington, DE) grafts (0.8 x 50.0 cm) were tunneled subcutaneously over the righ