Zobrazeno 1 - 10
of 24
pro vyhledávání: '"C M, Boyer"'
Autor:
F, Xu, S A, Leadon, Y, Yu, C M, Boyer, K, O'Briant, K, Ward, A, McWatters, X, Zhao, D S, Bae, K, DeSombre, M R, Zalutsky, R C, Bast
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(8)
Radionuclide conjugates or ricin A chain (RTA) immunotoxins that target pl85HER-2 have partially inhibited the growth of human ovarian cancer xenografts in athymic mice but generally have not cured mice bearing human tumor transplants. The present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17c34cff9da4dad5c8fe83dc765ced33
https://pubmed.ncbi.nlm.nih.gov/10955821
https://pubmed.ncbi.nlm.nih.gov/10955821
Autor:
C M, Boyer, L, Pusztai, J R, Wiener, F J, Xu, G S, Dean, B S, Bast, K C, O'Briant, M, Greenwald, K A, DeSombre, R C, Bast
Publikováno v:
International journal of cancer. 82(4)
Different epitopes on the extracellular domain of the HER-2 receptor can serve as distinct targets for immunotoxins. To determine the optimal epitope target for immunotoxin therapy, 7 anti-HER-2 ricin A chain murine monoclonal immunotoxins, each reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::172b70f3f6560a0734bcf1a6b5b633ec
https://pubmed.ncbi.nlm.nih.gov/10404066
https://pubmed.ncbi.nlm.nih.gov/10404066
Autor:
G S, Dean, L, Pusztai, F J, Xu, K, O'Briant, K, DeSombre, M, Conaway, C M, Boyer, J, Mendelsohn, R C, Bast
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(10)
Approximately 30% of ovarian and breast cancers overexpress p185(c-erbB-2) with as many as 10(6) receptors/cell. Normal cells have as few as 10(4) receptors/cell. We have examined the susceptibility of SKOv3 human ovarian cancer cells to anti-c-erbB2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e2e2b630c97fb2d8c8595c945b340a8
https://pubmed.ncbi.nlm.nih.gov/9796989
https://pubmed.ncbi.nlm.nih.gov/9796989
Autor:
R C, Bast, L, Pusztai, B J, Kerns, J A, MacDonald, P, Jordan, L, Daly, C M, Boyer, J, Mendelsohn, A, Berchuck
Publikováno v:
Hybridoma. 17(4)
Monoclonal antibodies (MAbs) and immunoconjugates reactive with different antigens expressed by neoplastic cells can inhibit tumor growth. Use of these agents in combination with one another or with chemotherapy can exert additive or synergistic cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b36af8fa8133215aa139e5992ea77ea7
https://pubmed.ncbi.nlm.nih.gov/9790065
https://pubmed.ncbi.nlm.nih.gov/9790065
Autor:
C, van Haaften-Day, P, Russell, C M, Boyer, B J, Kerns, J R, Wiener, D N, Jensen, R C, Bast, N F, Hacker
Publikováno v:
Cancer. 77(10)
Tumors of borderline malignancy are still a controversial subgroup of ovarian neoplasms. The expression of several cell regulatory proteins was studied to characterize the molecular phenotype of these tumors, and to compare them with their benign and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::262375b3da6f8ee2bab4f454ee28ad5f
https://pubmed.ncbi.nlm.nih.gov/8640675
https://pubmed.ncbi.nlm.nih.gov/8640675
Autor:
A. Berchuck, S. Wu, K. De Sombre, C. M. Boyer, G. B. Mills, R. C. Bast, S. Kassim, G. Rodriguez, Jon R. Wiener, J. A. Hurteau
Publikováno v:
Ovarian Cancer 3 ISBN: 9781475701388
Since the last Helene Harris Symposium two years ago, epithelial ovarian cancer has been shown to be a clonal disease [1,2]. Consequently, multiple genetic changes within a single cell are thought to be required for malignant transformation. Such eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ca495cc9bbb892ff29d8c7a4d7a09dc
https://doi.org/10.1007/978-1-4757-0136-4_11
https://doi.org/10.1007/978-1-4757-0136-4_11
Publikováno v:
Immunology series. 61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b181fe03def647c8a9c4d17277b39450
https://pubmed.ncbi.nlm.nih.gov/7912111
https://pubmed.ncbi.nlm.nih.gov/7912111
Autor:
S J, McKenzie, K A, DeSombre, B S, Bast, D R, Hollis, R S, Whitaker, A, Berchuck, C M, Boyer, R C, Bast
Publikováno v:
Cancer. 71(12)
The HER-2 neu (c-erbB-2) oncogene product p185neu is expressed by most ovarian cancers and overexpressed in approximately 30%.Sera from patients with ovarian cancer were evaluated for neu antigen using an enzyme-linked immunoassay and for CA 125 anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::513ce480636365df5369444af25e800c
https://pubmed.ncbi.nlm.nih.gov/8099528
https://pubmed.ncbi.nlm.nih.gov/8099528
Publikováno v:
Cancer. 71
As in the case of other epithelial neoplasms, most ovarian cancers arise from single clones of cells that have undergone multiple genetic alterations. A comparison of normal and malignant ovarian epithelium has identified several differences in growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac823808f79c8a0a56f00b1877a6e185
https://pubmed.ncbi.nlm.nih.gov/8431895
https://pubmed.ncbi.nlm.nih.gov/8431895
Publikováno v:
Cancer research. 51(19)
A murine monoclonal antibody, TA1, is directed against an epitope on the extracellular domain of the HER-2/neu (c-erbB-2) gene product. Requirements for TA1-induced internalization of c-erbB-2 have been studied using the SKBr3 human breast cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1903bf3de196e36597ece892810e25fb
https://pubmed.ncbi.nlm.nih.gov/1680547
https://pubmed.ncbi.nlm.nih.gov/1680547