Zobrazeno 1 - 10
of 24
pro vyhledávání: '"C M, Boulanger"'
Publikováno v:
British Journal of Clinical Pharmacology. 42:431-441
1. Rizatriptan (MK-462, (N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl] ethylamine)) and its structurally related analogue L-741,519 (N-methyl-4-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]piperidine) are novel 5-HT1D-receptor agonists. Rizatr
Publikováno v:
British Journal of Clinical Pharmacology. 42:431-441
Publikováno v:
The American Journal of Cardiology. 76:3E-12E
Endothelial cells can produce at least 3 substances which cause relaxation of vascular smooth muscle: (1) endothelium-derived nitric oxide (NO, which is secreted not only toward the underlying vascular smooth muscle but also into the blood vessel lum
Publikováno v:
ResearcherID
Experiments were designed to compare the relaxant activity of the new nitrate ester ITF 296 in isolated arteries and veins of the dog and to determine the extent of modulation by the endothelium of the response to the compound. Rings (with and withou
Publikováno v:
Journal of Cardiovascular Pharmacology. 23:869-876
Experiments were designed to determine whether the Ca2+ channel inhibitor RO 40-5967 [(1S,2S)-2-[2-[[3-(2-benzimidazolyl)propyl]methylamine]ethyl]-6- fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride] causes endothelium-
Publikováno v:
ResearcherID
Experiments were designed to determine whether or not indapamide, an antihypertensive agent with vasodilator properties, inhibits endothelium-dependent contractions. Rings of aortae with and without endothelium from spontaneously hypertensive rats (S
Publikováno v:
Biochemical and Biophysical Research Communications. 196:1261-1266
Induction of NO synthase expression by interleukin-1 beta in cultured vascular smooth muscle cells from rat aortas was accompanied by simultaneous induction of GTP: cyclohydrolase I. This enzyme regulates the de novo synthesis pathway for tetrahydrob
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H523-H529
The influence of the endothelial surface and its interaction with various plasma components on flow velocity was investigated in vitro. The falling velocity of microcarrier beads with and without cultured porcine aortic endothelial cells in a vertica
Publikováno v:
Annales de cardiologie et d'angeiologie. 57(3)
Cell activation or apoptosis leads to plasma membrane blebbing and microparticles (MPs) release. MPs are submicron membrane vesicles expressing a panel of oxidized phospholipids and proteins specific of the cells they originate from. Exposure of nega
Publikováno v:
British journal of pharmacology. 131(4)
Experiments were designed to investigate the role of cyclo-oxygenase isoforms in endothelial dysfunction in ageing. Aortic rings with endothelium of aged and young (24 vs 4 month-old) Wistar rats, were mounted in organ chambers for the recording of c