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Réalisation d’un diagnostic partagé du territoire dans le domaine santé travail sous forme cartographique

Autor: P. Bossi, C. Levrat-Pinatel, S. Garcia, M. Delaunay

Publikováno v: Archives des Maladies Professionnelles et de l'Environnement. 81:86

Objectifs Dans le cadre des travaux du Plan Regional Sante Travail 3 Occitanie (PRST3), une experimentation a ete mise en place avec le Service de Sante au Travail d’Ales (SST CMIST), visant a tester et deployer des methodes de cartographie statist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c67b2465a4d8cac68b18815be5e7580b
https://doi.org/10.1016/j.admp.2019.12.062

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Inactivation of wild-type p53 by a dominant negative mutant renders MCF-7 cells resistant to tubulin-binding agent cytotoxicity

Autor: N Voorzanger-Rousselot, A Vanier-Viornery, Alain Puisieux, Carlos M. Galmarini, O Roesch-Gateau, C Levrat, Eric Tabone, Charles Dumontet, R. A. Britten, Nicole Falette

Publikováno v: British Journal of Cancer

The present study was performed to gain insight into the role of p53 on the cytotoxicity of tubulin-binding agents (TBA) on cancer cells. Drug sensitivity, cell cycle distribution and drug-induced apoptosis were compared in 2 lines derived from the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585e1fa0e128c18a679f6d369239e7d9
https://doi.org/10.1054/bjoc.2001.2017

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Calcium-binding properties of the mitochondrial channel-forming hydrophobic component

Autor: O, Gateau-Roesch, E, Pavlov, A V, Lazareva, E A, Limarenko, C, Levrat, N E, Saris, P, Louisot, G D, Mironova

Publikováno v: Journal of bioenergetics and biomembranes. 32(1)

A hydrophobic, low-molecular weight component extracted from mitochondria forms a Ca2+-activated ion channel in black-lipid membranes (Mironova et al., 1997). At pH 8.3-8.5, the component has a high-affinity binding site for Ca2+ with a Kd of 8 x 10(

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6614e4cc8cef8d15f7d6ee2389725cc2
https://pubmed.ncbi.nlm.nih.gov/11768755

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Palmitic and stearic acids bind Ca2+ with high affinity and form nonspecific channels in black-lipid membranes. Possible relation to Ca2+-activated mitochondrial pores

Autor: G D, Mironova, O, Gateau-Roesch, C, Levrat, E, Gritsenko, E, Pavlov, A V, Lazareva, E, Limarenko, C, Rey, P, Louisot, N E, Saris

Publikováno v: Journal of bioenergetics and biomembranes. 33(4)

A mitochondrial hydrophobic component that forms Ca2+-induced nonspecific ion channels in black-lipid membranes (Mironova et al., 1997) has been purified and its nature elucidated. It consists of long-chain saturated fatty acids--mainly palmitic and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8090bb42af176f9ab01c1e9e449528bd
https://pubmed.ncbi.nlm.nih.gov/11710807

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Akademický článek

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Study of the succinate dehydrogenase activation in permeabilized mitochondria through the Ca(2+)-stimulated phospholipase A2

Autor: C, Levrat, P, Louisot

Publikováno v: Biochemistry and molecular biology international. 34(3)

The development of a mitochondrial membrane permeability triggered by the Ca(2+)-stimulation of PLA2 (phospholipase A2; EC 3.1.1.4.) and based on swelling, polyunsaturated fatty acids release and calcium influx, induced the activation of SDH (succina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ce3fe3954e53ebfabb21deb4befa8f6
https://pubmed.ncbi.nlm.nih.gov/7833834

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Mitochondrial contact sites. Lipid composition and dynamics

Autor: D, Ardail, J P, Privat, M, Egret-Charlier, C, Levrat, F, Lerme, P, Louisot

Publikováno v: The Journal of biological chemistry. 265(31)

Two membrane fractions of intermediate density between inner and outer mitochondrial membranes were isolated by density gradient centrifugation from osmotically lysed mitochondria and mitoplasts of liver. These fractions were characterized by the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a2f5099673121e7a8b1235404a0995ab
https://pubmed.ncbi.nlm.nih.gov/2172233

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Biosynthesis of glycoconjugates in mitochondrial outer membranes. Preliminary characterization of the oligosaccharide moiety of a N-glycoprotein

Autor: C, Levrat, D, Ardail, P, Louisot

Publikováno v: Biochemistry international. 20(1)

Outer mitochondrial membranes synthesize a N-glycoprotein by a direct incorporation of sugars from their nucleotide-donors into an endogenous protein acceptor. To characterize the oligosaccharide moiety of this N-glycoprotein, we sequentially incorpo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f41be4d1e0193aab344b2c27c4c1be5c
https://pubmed.ncbi.nlm.nih.gov/2328016

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Biosynthesis of dolichyl pentasaccharide diphosphate in calf pancreas microsomes

Autor: C D Warren, C Levrat, W Sasak, R W Jeanloz

Publikováno v: Journal of Biological Chemistry. 259:332-337

Incubation of synthetic dolichyl pyrophosphate tetrasaccharide and GDP-[14C]mannose with calf pancreas microsomes gave three lipid-linked oligosaccharides, which could be extracted with chloroform/methanol (2:1) and separated on silica gel plates. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::833f3251fe2b2bd3c5e88df1cd106cd1
https://doi.org/10.1016/s0021-9258(17)43662-3

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