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Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments

Autor: C Layet, Oddmund Bakke, J W Yewdell, Paola Romagnoli, Ronald N. Germain

Publikováno v: The Journal of Experimental Medicine

Invariant chain (Ii), which associates with major histocompatibility complex (MHC) class II molecules in the endoplasmic reticulum, contains a targeting signal for transport to intracellular vesicles in the endocytic pathway. The characteristics of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4b787437f2429688ef074bd809f678
https://doi.org/10.1084/jem.177.3.583

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Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex A alpha A beta dimers from the endoplasmic reticulum/cis-Golgi compartment

Autor: Ronald N. Germain, C Layet

Publikováno v: Proceedings of the National Academy of Sciences. 88:2346-2350

Invariant chain (Ii) is a nonpolymorphic, non-major histocompatibility complex (MHC)-encoded glycoprotein that rapidly associates with newly synthesized class II MHC alpha and beta chains in the rough endoplasmic reticulum. This oligomerization of Ii

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddd163cda07c5f0437ee6424d41616d
https://doi.org/10.1073/pnas.88.6.2346

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The association between murine beta 2-microglobulin and HLA class I heavy chains results in serologically detectable conformational changes of both chains

Autor: P Ferrier, C Layet, D H Caillol, B R Jordan, F A Lemonnier

Publikováno v: The Journal of Immunology. 135:1281-1287

HLA-A3-, HLA-B7-, and HLA-CW3-transfected L cells, maintained in medium supplemented with murine serum so as to ensure that the human heavy chains were associated with murine beta 2-microglobulin, were subjected to a systematic serologic analysis for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76d00c5394c3a7fc3b2311cacce71355
https://doi.org/10.4049/jimmunol.135.2.1281

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Transformation of LMTK- cells with purified class I genes. V. Antibody-induced structural modification of HLA class I molecules results in potentiation of the fixation of a second monoclonal antibody

Autor: F A Lemonnier, P P Le Bouteiller, D Olive, B Malissen, Z Mishal, C Layet, J Dubreuil, D H Caillol, F M Kourilsky, B R Jordan

Publikováno v: The Journal of Immunology. 132:1176-1182

A potentiation phenomenon was observed with HLA-A3 and CW3 transformed murine L cells between anti-HLA class I B10.6 (potentiated) and B10.8 (potentiating) monoclonal antibodies (m.Ab.). Further studies of this phenomenon with these transformed L cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc2c2d5fc17b526cfd601ef49f575945
https://doi.org/10.4049/jimmunol.132.3.1176

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Transfection of murine LMTK? cells with purified HLA class I genes

Autor: François Lemonnier, Pierre Ferrier, Brigitte Kahn-Perlès, M.-J. Santoni, Torn Strachan, C Layet, Joséphine Sire, Régis Sodoyer, Bertrand Jordan

Publikováno v: Immunogenetics. 23:246-251

The individual contributions of the first two external domains of the HLA-B7 heavy chain to the expression of allele-specific (B7) and locus-specific (B and C) antigenic determinants were investigated using hybrid class I genes. Hybrid genes were con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b3cf7181975925f0fa546df079e6c0
https://doi.org/10.1007/bf00373019

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Serological and structural analysis of HLA class I molecules: β2-microglobulin interacts with the two external domains of the HLA class I heavy chain

Autor: François Lemonnier, Razqallah Hakem, Joséphine Sire, Brigitte Kahn-Perlès, A. Gillet, Pierre Pontarotti, J. Roudier, Antoine Toubert, P. Le Bouteiller, B. Perarnau, C Layet, Pierre Ferrier

Publikováno v: Annales de l'Institut Pasteur / Immunologie. 138:19-35

The serological reactivities of HLA class I molecules were studied in relation to structural modifications of these molecules, including shuffling of external exons and exchange of human beta 2-microglobulin for beta 2-microglobulin from different sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d86f240dd8437a7c11b61aa469d7a7
https://doi.org/10.1016/s0769-2625(87)80093-4

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Akademický článek

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Akademický článek

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