Zobrazeno 1 - 10
of 151
pro vyhledávání: '"C Laker"'
Publikováno v:
Applied and Environmental Soil Science, Vol 2024 (2024)
Soil crusting (surface sealing) is widespread and serious in ecotouristic game parks and reserves in southern Africa, and especially South Africa. In this study, mineral soil crusts were found to be the problem in the Dinokeng Game Reserve (DGR), Sou
Externí odkaz:
https://doaj.org/article/40cd547f773e4ae6b35c4872d1b1612f
Autor:
Michiel C. Laker
Publikováno v:
Mining, Vol 3, Iss 2, Pp 205-220 (2023)
Gold mining has serious negative environmental impacts, especially due to pollution emanating from tailings storage facilities (TSFs, tailings dams, slimes dams). The most important forms of pollution from TSFs are acid mine drainage (AMD) and high l
Externí odkaz:
https://doaj.org/article/9126136283db465aba05cc83f2c7c523
Autor:
Brandon B. Boland, Rhianna C. Laker, Siobhan O'Brien, Sadichha Sitaula, Isabelle Sermadiras, Jens Christian Nielsen, Pernille Barkholt, Urmas Roostalu, Jacob Hecksher-Sørensen, Sara Rubek Sejthen, Ditte Dencker Thorbek, Arthur Suckow, Nicole Burmeister, Stephanie Oldham, Sarah Will, Victor G. Howard, Benji M. Gill, Philip Newton, Jacqueline Naylor, David C. Hornigold, Jotham Austin, Louise Lantier, Owen P. McGuinness, James L. Trevaskis, Joseph S. Grimsby, Christopher J. Rhodes
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101392- (2022)
Objective: Obesity-linked type 2 diabetes (T2D) is a worldwide health concern and many novel approaches are being considered for its treatment and subsequent prevention of serious comorbidities. Co-administration of glucagon like peptide 1 (GLP-1) an
Externí odkaz:
https://doaj.org/article/b325ef86371a42baa07ae1549ba9e3b0
Autor:
Lewin Small, Lars R Ingerslev, Eleonora Manitta, Rhianna C Laker, Ann N Hansen, Brendan Deeney, Alain Carrié, Philippe Couvert, Romain Barrès
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1009325 (2021)
In response to physical exercise and diet, skeletal muscle adapts to energetic demands through large transcriptional changes. This remodelling is associated with changes in skeletal muscle DNA methylation which may participate in the metabolic adapta
Externí odkaz:
https://doaj.org/article/b980783ce524444ea61f6aac736af9c6
Autor:
Rhianna C. Laker, Joshua C. Drake, Rebecca J. Wilson, Vitor A. Lira, Bevan M. Lewellen, Karen A. Ryall, Carleigh C. Fisher, Mei Zhang, Jeffrey J. Saucerman, Laurie J. Goodyear, Mondira Kundu, Zhen Yan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Exercise is associated with biogenesis and removal of dysfunctional mitochondria. Here the authors use a mitochondrial reporter gene to demonstrate the occurrence of mitophagy following exercise in mice, and show this is dependent on AMPK and ULK1 si
Externí odkaz:
https://doaj.org/article/45800b0013144c79a5f7f403114864d6
Autor:
Zhen Yan, Ana Kronemberger, Jay Blomme, Jarrod A. Call, Hannah M. Caster, Renata O. Pereira, Henan Zhao, Vitor U. de Melo, Rhianna C. Laker, Mei Zhang, Vitor A. Lira
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Autophagy is stimulated by exercise in several tissues; yet the role of skeletal and cardiac muscle-specific autophagy on the benefits of exercise training remains incompletely understood. Here, we determined the metabolic impact of exercise
Externí odkaz:
https://doaj.org/article/74eacc2c370844829f2d479d16461e8f
Publikováno v:
South African Journal of Plant and Soil. 38:217-230
Pressures from population growth, changing diets and climate change are driving transformation of our global food production to ensure more efficient, reliable and sustainable production. In South ...
Autor:
Gerhardus Petrus Nortjé, M. C. Laker
Publikováno v:
South African Journal of Plant and Soil. 38:247-257
Conservation agriculture (CA) is an integrated approach that consists of a suite of practices, namely no-till farming, cover crops, and crop rotation that includes at least three crops. In the glob...
Publikováno v:
South African Journal of Plant and Soil. 38:202-216
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167910 (2016)
The mitochondrial permeability transition pore (mPTP) is a key regulator of mitochondrial function that has been implicated in the pathogenesis of metabolic disease. Cyclophilin D (CypD) is a critical regulator that directly binds to mPTP constituent
Externí odkaz:
https://doaj.org/article/18930712b92d4218a2d936d2c0b62211