Zobrazeno 1 - 10
of 43
pro vyhledávání: '"C L Witzleben"'
Publikováno v:
Pediatric Pathology. 12:269-274
Publikováno v:
Journal of Clinical Investigation. 86:1038-1045
Reovirus type 1, after intravenous inoculation in the adult mouse, is secreted via bile into the intestine in an infectious form. Although reovirus type 1 is rapidly removed from systemic circulation by the liver and the lung, very few hepatocytes ex
Publikováno v:
The Journal of Experimental Medicine
Adult severe combined immunodeficient (SCID) mice can be infected by the oral route with reovirus, and a systemic infection can be established. Infectious virus is recovered from all internal organs, and the mice die in 4-6 wk. Chronic, discrete infl
Autor:
Victoria E.H. Carlton, B. B. Dahms, Joseph DeYoung, J. Reyes, D. A. Piccoli, C. L. Witzleben, Laura N. Bull, F. J. Dicarlo, N. C. O'connell, K. D. R. Setchell, N. L. Stricker, M. S. Magid, S A Kocoshis, E. Kahn, P. R. Faught, J. F. Fitzgerald, Nelson B. Freimer, J T Boyle, L. Mcloughlin, A. S. Knisely, R. M. Agostini, Siamak Baharloo, John S. Markowitz
Publikováno v:
Hepatology (Baltimore, Md.). 26(1)
Byler disease (ByD) is an autosomal recessive disorder in which cholestasis of onset in infancy leads to hepatic fibrosis and death. Children who have a clinically similar disorder, but are not members of the Amish kindred in which ByD was described,
Publikováno v:
Pediatrics. 87(4)
Ordinarily, severe disease due to acquired cytomegalovirus (CMV) infection does not occur in immunocompetent children. We describe a previously healthy boy who acquired primary CMV infection at approximately 2 years of age and experienced a 2-year-lo
Reovirus type 1 strain Lang is restricted from replicating in adult murine livers. In noninjured livers, approximately 1% of hepatocytes express reovirus antigen during infection. However, hepatocytes can be induced to express reovirus antigen if cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd3f5a1795d02ef6f52c2fcff9f1d78
https://europepmc.org/articles/PMC247936/
https://europepmc.org/articles/PMC247936/
Autor:
C. L. Witzleben, Richard A. Landy
Publikováno v:
Cancer. 34:786-790
Publikováno v:
Journal of Virology. 61:3222-3226
We have previously demonstrated that mammalian reovirus type 1 enters the bile and gut lumen after systemic administration. In the present study, we showed that Kupffer cell uptake is essential for the transport of reovirus into the bile. Furthermore
Autor:
C. L. Witzleben
Publikováno v:
Annals of the New York Academy of Sciences. 165:105-110
Autor:
C. L. Witzleben
Publikováno v:
Pediatrics. 32:31-35
A case of tracheal aplasia is described, and the literature concerning this rare anomaly is reviewed. The lesion has so far been uniformly fatal. Infants with this condition have severe early respiratory distress and may present a difficult problem i