Zobrazeno 1 - 10
of 50
pro vyhledávání: '"C L Sidman"'
Autor:
C L Sidman, J B Roths
Publikováno v:
Infection and Immunity. 61:1641-1649
Homozygous mutant scid/scid (severe combined immunodeficiency) mice (referred to as scid mice) lack both specific humoral and cell-mediated immune functions and are exemplary in vivo models for analysis of host-parasite relationships. In our colony,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a89122393062c16a34b581e9f027065
https://doi.org/10.1128/iai.61.5.1641-1649.1993
https://doi.org/10.1128/iai.61.5.1641-1649.1993
Publikováno v:
The Journal of Experimental Medicine
Mice homozygous for the mutant allele scid (severe combined immunodeficiency) have been described as excellent models for Pneumocystis carinii (Pc) pneumonia (PCP), a major health problem in patients with acquired immune deficiency syndrome (AIDS) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcf2525bf98244e17282ace4e3bd7a6
https://doi.org/10.1084/jem.177.4.1193
https://doi.org/10.1084/jem.177.4.1193
Autor:
V S Prasad, C L Sidman
Publikováno v:
The Journal of Immunology. 147:4200-4206
Homozygosity for either of the mutations lpr (lymphoproliferation) or gld (generalized lymphoproliferative disease) in mice results in lymphoproliferation and autoimmune disease. To investigate the site and time of excessive lymphocyte proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41febb7a161368e43262a7fb336cdb4e
https://doi.org/10.4049/jimmunol.147.12.4200
https://doi.org/10.4049/jimmunol.147.12.4200
Germline V genes encode viable motheaten mouse autoantibodies against thymocytes and red blood cells
Publikováno v:
The Journal of Immunology. 145:2304-2311
Autoantibodies against thymocytes and RBC may contribute to the pathophysiology of homozygous viable motheaten (mev) autoimmune disease. Whether the production of these autoantibodies in mev mouse results from polyclonal nonspecific B cell activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbe0cd2eb9c34c4d77141732c7718493
https://doi.org/10.4049/jimmunol.145.7.2304
https://doi.org/10.4049/jimmunol.145.7.2304
Publikováno v:
Infection and Immunity. 61:1586-1588
scid mice naturally infected with Pneumocystis carinii and inoculated with a normally apathogenic pneumovirus had significantly higher P. carinii cyst counts and developed significantly more severe P. carinii-related disease than did sham-inoculated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a49486a92bd7c956a420f43c721ab88
https://doi.org/10.1128/iai.61.4.1586-1588.1993
https://doi.org/10.1128/iai.61.4.1586-1588.1993
Publikováno v:
Bone marrow transplantation. 22(4)
This report describes a child with a severe phenotype of autoimmune lymphoproliferative syndrome (ALPS) who developed progressive disease requiring stem cell transplantation. This severe form of ALPS was associated with a novel Fas gene splice site m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb60668a46b85d0d8dca507d73552e7
https://pubmed.ncbi.nlm.nih.gov/9722073
https://pubmed.ncbi.nlm.nih.gov/9722073
Publikováno v:
Molecular carcinogenesis. 18(2)
E(mu)-myc transgenic mice carry a constitutively overexpressed c-myc oncogene and develop B-lineage lymphomas. Previous studies have shown that c-myc overexpression can lead to in vitro apoptosis. Here, we investigated the in vivo effects of altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94e6977810cad2abb65ca558e957b484
https://pubmed.ncbi.nlm.nih.gov/9049182
https://pubmed.ncbi.nlm.nih.gov/9049182
Publikováno v:
Cytometry. 23(2)
The clinically important issue of tumor heterogeneity was studied in C57BL/6-E mu-myc transgenic mice, which provide a genetically uniform model system in which all animals eventually develop B cell lymphomas after additional genetic changes beyond e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da5a35b2b9abb93ef41f84450a48a2a7
https://pubmed.ncbi.nlm.nih.gov/8742172
https://pubmed.ncbi.nlm.nih.gov/8742172
Publikováno v:
Bone marrow transplantation. 15(4)
Although many cytokines have been previously implicated in graft-versus-host disease (GVHD), no study to date has comprehensively evaluated their expression over time or in different tissues affected by GVHD. Using a semi-quantitative reverse transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cfd46fae7ebc798a5382564fc66e6db
https://pubmed.ncbi.nlm.nih.gov/7655387
https://pubmed.ncbi.nlm.nih.gov/7655387
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(4)
Homozygosity for either of the autosomal recessive mutations, lpr or gld, confers an autoimmune syndrome characterized by massive lymphoid hyperplasia and extensive autoantibody production. Despite the similarities in disease progression, functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7aca0f039deef2de94b2cedfd73d9e7c
https://pubmed.ncbi.nlm.nih.gov/8120369
https://pubmed.ncbi.nlm.nih.gov/8120369