Zobrazeno 1 - 5
of 5
pro vyhledávání: '"C L Raiford"'
Publikováno v:
The Journal of Immunology. 144:3822-3828
We investigated, in vitro and in vivo, the cyclosporin A (CsA) regulation of LPS-induced TNF gene expression and subsequent pathophysiologic changes. In vitro dose-response kinetics data showed that CsA inhibited TNF bioactivity in the supernatant wi
Autor:
D T, Nguyen, M K, Eskandai, L E, DeForge, C L, Raiford, R M, Strieter, S L, Kunkel, D G, Remick
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(10)
We investigated, in vitro and in vivo, the cyclosporin A (CsA) regulation of LPS-induced TNF gene expression and subsequent pathophysiologic changes. In vitro dose-response kinetics data showed that CsA inhibited TNF bioactivity in the supernatant wi
Autor:
D G, Remick, R M, Strieter, M K, Eskandari, D T, Nguyen, M A, Genord, C L, Raiford, S L, Kunkel
Publikováno v:
The American journal of pathology. 136(1)
Tumor necrosis factor-alpha (TNF) has been implicated strongly as a principal mediator in the pathogenesis of septic shock. The authors investigated the in vivo production of TNF in CBA/J and CD-1 mice that had been primed by an intraperitoneal injec
Autor:
Daniel G. Remick, Rory M. Marks, M. Genord, Mark K. Eskandari, Sem H. Phan, C. L. Raiford, Steven L. Kunkel, H. J. Showell, Robert M. Strieter, Joseph P. Lynch
Publikováno v:
Journal of Biological Chemistry. 264:10621-10626
Although fibroblasts are important in providing a structural framework for most tissues, they also appear to be active participants in the inflammatory process via the production of specific mediators. The production of inflammatory mediators by fibr
Autor:
Steven L. Kunkel, M. Genord, Daniel G. Remick, Robert M. Strieter, Joseph P. Lynch, C. L. Raiford, Robert N. Spengler
Publikováno v:
American journal of respiratory cell and molecular biology. 1(1)
Human tumor necrosis factor-alpha (TNF), a mononuclear phagocyte (MO)-derived peptide, is increasingly being recognized for its pleomorphic immunologic effects. A number of studies have demonstrated that LPS can induce TNF synthesis, but data examini