Zobrazeno 1 - 10
of 57
pro vyhledávání: '"C L Phillips"'
Autor:
Matthew C. L. Phillips, Martin Picard
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-21 (2024)
Abstract Neurodegenerative disorders are typically “split” based on their hallmark clinical, anatomical, and pathological features, but they can also be “lumped” by a shared feature of impaired mitochondrial biology. This leads us to present
Externí odkaz:
https://doaj.org/article/975a5dad0c274bd5b2465f336718f6ca
Autor:
Matthew C. L. Phillips, Samuel E. Johnston, Pat Simpson, David K. Chang, Danielle Mather, Rognvald J. Dick
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disorder. The most devastating variant is bulbar-onset ALS, which portends a median survival of 24 months from the onset of symptoms. Abundant evidence indicates that neuron metabo
Externí odkaz:
https://doaj.org/article/4e88d55051f1487cae4431a13ca018ee
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Huntington's disease (HD) is a progressive, fatal neurodegenerative disorder with limited treatment options. Substantial evidence implicates mitochondria dysfunction in brain and skeletal muscle in the pathogenesis of HD. Metabolic strategies, such a
Externí odkaz:
https://doaj.org/article/97d7a5a1a952445db5db18a13c2529bb
Autor:
Matthew C. L. Phillips, Laura M. Deprez, Grace M. N. Mortimer, Deborah K. J. Murtagh, Stacey McCoy, Ruth Mylchreest, Linda J. Gilbertson, Karen M. Clark, Patricia V. Simpson, Eileen J. McManus, Jee-Eun Oh, Satish Yadavaraj, Vanessa M. King, Avinesh Pillai, Beatriz Romero-Ferrando, Martijn Brinkhuis, Bronwyn M. Copeland, Shah Samad, Shenyang Liao, Jan A. C. Schepel
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract Background Brain energy metabolism is impaired in Alzheimer’s disease (AD), which may be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine whether a 12-week modified ketogenic diet improved cognition, da
Externí odkaz:
https://doaj.org/article/70dd2699502f44b381a8555e3317d0f2
Autor:
V. Minard-Colin, J. Buechner, F. Locatelli, B. Gonzalez Martinez, B. J. Vormoor, S. Cooper, J. Krueger, S. Napolitano, A. Attarbaschi, A. Baruchel, S. Ghorashian, M. L. Hermiston, H. Hiramatsu, M. Ifversen, S. John, S. L. Khaw, T. A. O’Brien, C. L. Phillips, C. Diaz de Heredia, D. Tomizawa, K. Vettenranta, A. S. Wayne, S. Newsome, R. Awasthi, S. Redondo, A. Masood, S. L. Maude, B. Burkhardt
Publikováno v:
HemaSphere, Vol 6, Pp 156-157 (2022)
Externí odkaz:
https://doaj.org/article/1deff0dd936f41be913eeafb373585cc
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Sporadic inclusion body myositis (IBM) is a chronic inflammatory and degenerative muscle disease with limited treatment options; no therapy can alter its natural course. Ketogenic diets are theoretically capable of suppressing inflammation, enhancing
Externí odkaz:
https://doaj.org/article/a122e8297fed409da0ec5695bf65afd2
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Thymomas consist of neoplastic thymic cells intermixed with variable numbers of non-neoplastic lymphocytes. Metastatic thymomas are typically managed with non-curative chemotherapy to control tumor-related symptoms; no prolonged survival is expected.
Externí odkaz:
https://doaj.org/article/837614151ced4e7585bd5259efc46ccc
Autor:
M. C. L. Phillips, J. Leyden, E. J. McManus, D. G. Lowyim, F. Ziad, B. G. Moon, N. A. B. Haji Mohd Yasin, A. Tan, Z. Thotathil, M. B. Jameson
Publikováno v:
Journal of Oncology. 2022:1-10
Background. Glioblastoma multiforme (GBM) may be susceptible to metabolic strategies such as fasting and ketogenic diets, which lower blood glucose and elevate ketones. Combining these two strategies may be an ideal approach for sustaining a potentia
Autor:
M Pengo, E I Schwarz, F Barbe, L Drager, C Fava, M S M Ip, M A Martinez Garcia, D McEvoy, Y Peker, C L Phillips, D Soranna, J Steier, J Stradling, A Zambon, G Parati
Publikováno v:
European Heart Journal. 43
Background Obstructive sleep apnoea (OSA) is a well-known cardiovascular risk factor and is frequently associated with hypertension. The treatment of OSA with continuous positive airway pressure (CPAP) can resolve apnoeas, hypoxia, and sympathetic hy
Publikováno v:
Biogeosciences, Vol 10, Iss 12, Pp 7999-8012 (2013)
While radiocarbon (14C) abundances in standing stocks of soil carbon have been used to evaluate rates of soil carbon turnover on timescales of several years to centuries, soil-respired 14CO2 measurements are an important tool for identifying more imm
Externí odkaz:
https://doaj.org/article/c9bc1d258fee4791b6e3c84e152b153b