Zobrazeno 1 - 6
of 6
pro vyhledávání: '"C L, Szumlanski"'
Publikováno v:
Journal of Biological Chemistry. 269:14835-14840
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines. Human liver NNMT activity has a bimodal frequency distribution, an observation which raises the possibility that this enzyme activity might be re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0992db7491f96e7081a97c2e80e415c5
https://doi.org/10.1016/s0021-9258(17)36700-5
https://doi.org/10.1016/s0021-9258(17)36700-5
Publikováno v:
American journal of medical genetics. 96(3)
Histamine is a central nervous system (CNS) neurotransmitter that has been implicated in the pathophysiology of schizophrenia. Histamine N-methyltransferase (HNMT) terminates the neurotransmitter actions of histamine in the mammalian CNS, and levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3998532fc781d3b4d377e96b10421e5
https://pubmed.ncbi.nlm.nih.gov/10898922
https://pubmed.ncbi.nlm.nih.gov/10898922
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(8)
2,6-Dithiopurine (DTP) has been proposed as a possible chemopreventive agent because of its facile reaction with the electrophilic ultimate carcinogen, benzo[a]pyrene diol epoxide, and other reactive electrophiles. Previous studies in mouse skin indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5d94f992f8056bbf630a44b9c56e754
https://pubmed.ncbi.nlm.nih.gov/7493553
https://pubmed.ncbi.nlm.nih.gov/7493553
Publikováno v:
The Journal of biological chemistry. 269(20)
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines. Human liver NNMT activity has a bimodal frequency distribution, an observation which raises the possibility that this enzyme activity might be re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b88d93b4b7e0b2b5a0dd087f124a854a
https://pubmed.ncbi.nlm.nih.gov/8182091
https://pubmed.ncbi.nlm.nih.gov/8182091
Publikováno v:
Biochemical pharmacology. 44(4)
Thiopurine methyltransferase (TPMT) catalyzes the S-methylation of heterocyclic and aromatic sulfhydryl compounds such as the thiopurine drug 6-mercaptopurine (6-MP). TPMT activity in human tissue is regulated by a common genetic polymorphism, and "p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f43d2764f28566b5d56927d49c953946
https://pubmed.ncbi.nlm.nih.gov/1510725
https://pubmed.ncbi.nlm.nih.gov/1510725
Publikováno v:
Pharmacogenetics. 2(4)
Thiopurine methyltransferase (TPMT) catalyses the S-methylation of thiopurine drugs such as 6-mercaptopurine (6-MP). TPMT activity in the human red blood cell (RBC) is controlled by a common genetic polymorphism. Gene frequencies for this polymorphis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2afa84fced4780c7213e4c6dfb5e069
https://pubmed.ncbi.nlm.nih.gov/1306116
https://pubmed.ncbi.nlm.nih.gov/1306116