Zobrazeno 1 - 10
of 51
pro vyhledávání: '"C L, Schauf"'
Publikováno v:
The Journal of General Physiology
In Myxicola giant axons the time constants for activation of the potassium conductance (GK) after prepulses less depolarized than a test pulse are comparable to the time constants for turn off of GK after prepulses more depolarized than the same test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04436d281b6b78c5bb865dec40296db
https://doi.org/10.1085/jgp.68.4.397
https://doi.org/10.1085/jgp.68.4.397
Publikováno v:
Annals of Neurology. 18:443-450
The mode of action of adrenocorticotropic hormone (ACTH) treatment in exacerbating multiple sclerosis was studied by short-term infusions of agents that mimic specific and limited pharmacological actions of ACTH and observing for temporally phase-loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02c966051d6c1ef1f4e9cf17880ce47
https://doi.org/10.1002/ana.410180406
https://doi.org/10.1002/ana.410180406
Autor:
C. L. Schauf
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 65:568-573
Time- and voltage-dependent behavior of the Na+ conductance in dialyzed intact Myxicola axons was compared with cut-open axons subjected to loose-patch clamp of the interior and to axons where Gigaseals were formed after brief enzyme digestion. Volta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75b45c641cd502dc86e9a7dada6b09b
https://doi.org/10.1139/y87-096
https://doi.org/10.1139/y87-096
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 39:680-685
The effects of sera from guinea-pigs with experimental allergic encephalomyelitis (EAE) and multiple sclerosis (MS) patients were evaluated and compared with the activity of control sera using the isolated frog spinal cord. Ventral root responses (VR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4c8d39c8da937e9ca99807d5bb5386
https://doi.org/10.1136/jnnp.39.7.680
https://doi.org/10.1136/jnnp.39.7.680
Autor:
C L Schauf, F A Davis
Publikováno v:
The Journal of General Physiology
Myxicola giant axons were studied using standard voltage-clamp techniques in solutions whose pH values ranged from 3.9 to 10.2. Buffer concentrations of 50 mM or greater were necessary to demonstrate the full effect of pH. In acidic solutions the axo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3717c31adc41606e0cc31c83cb0ecb8c
https://doi.org/10.1085/jgp.67.2.185
https://doi.org/10.1085/jgp.67.2.185
Publikováno v:
Biophysical Journal. 16:985-989
Myxicola giant axons internally injected with tetraethylammonium chloride to block potassium currents were examined under voltage clamp. The sodium inactivation time constants obtained from the decline in INa during step depolarizations were substant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2d629e3cdb1c3631b6011a8651976b
https://doi.org/10.1016/s0006-3495(76)85749-9
https://doi.org/10.1016/s0006-3495(76)85749-9
Publikováno v:
Biophysical Journal. 16:771-778
Sodium inactivation and reactivation have been examined in voltage-clamped Myxicola axons after long-lasting membrane depolarizations produced either directly by changes in holding potential or indirectly by elevation of external K+ concentration. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fab268beff4881d951a870329b358d7
https://doi.org/10.1016/s0006-3495(76)85727-x
https://doi.org/10.1016/s0006-3495(76)85727-x
Autor:
C. L. Schauf
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 14:273-281
SUMMARY 1. Drugs can be identified that relieve clinical symptoms of demyelinating diseases such as multiple sclerosis based on their ability to alter voltage-dependent ion channels in membranes and restore conduction in demyelinated nerve. Beneficia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1849fb0f0ea53c5e2b8bd33b0d1b051b
https://doi.org/10.1111/j.1440-1681.1987.tb00972.x
https://doi.org/10.1111/j.1440-1681.1987.tb00972.x
Autor:
C L Schauf, J O Bullock
Publikováno v:
The Journal of Physiology. 286:157-171
1. Immobilization of gating charge was examined in Myxicola giant axons dialysed with Cs+. 2. With increasing pulse durations the ratio QOFF/QON decreases to as little as 0.25 with a time constant of 3.2 msec determined from composite data. Na inacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0910f332b153f60f457a1847b026e299
https://doi.org/10.1113/jphysiol.1979.sp012611
https://doi.org/10.1113/jphysiol.1979.sp012611
Autor:
C. L. Schauf
Publikováno v:
The Journal of Physiology. 235:197-205
1. The temperature dependence of the sodium and potassium conductances of Myxicola giant axons was studied in the range of 1-18 degrees C.2. Analysis of voltage clamp records for step depolarizations of 20-150 mV yielded Q(10)'s for g(Na), g(K), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb8ac0a24ba31439087a274dc61acbb
https://doi.org/10.1113/jphysiol.1973.sp010384
https://doi.org/10.1113/jphysiol.1973.sp010384