Zobrazeno 1 - 5
of 5
pro vyhledávání: '"C L, Rivier"'
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 65(2)
Degarelix is a potent very long-acting GnRH antagonist after subcutaneous administration. In this paper, we describe the synthesis of two analogs of degarelix incorporating racemic 3-(2-methoxy-5-pyridyl)-alanine (2-OMe-5Pal, 5) at position 3. The tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0435a81fb1ebe93b58e2fc8173c41d9d
https://pubmed.ncbi.nlm.nih.gov/15705170
https://pubmed.ncbi.nlm.nih.gov/15705170
Autor:
J E, Rivier, G, Jiang, R S, Struthers, S C, Koerber, J, Porter, L A, Cervini, D A, Kirby, A G, Craig, C L, Rivier
Publikováno v:
Journal of medicinal chemistry. 43(5)
In three earlier papers, the structures and biological potencies of numerous mono- and dicyclic antagonists of GnRH were reported. Among these, two families, each containing two to four members were identified that had very high antagonist potencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fc00dd273345a73ae7212380b1b6925
https://pubmed.ncbi.nlm.nih.gov/10715149
https://pubmed.ncbi.nlm.nih.gov/10715149
Publikováno v:
Alcoholism, clinical and experimental research. 23(1)
Prenatal alcohol exposure has been shown to produce hyperresponsiveness of the hypothalamic-pituitary-adrenal (HPA) axis to immune challenges. Because cytokines, which are released in response to immune challenges, are known to activate the HPA axis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf4c911e14081be7570246c881b209d6
https://pubmed.ncbi.nlm.nih.gov/10029203
https://pubmed.ncbi.nlm.nih.gov/10029203
Autor:
A V, Turnbull, C L, Rivier
Publikováno v:
Endocrinology. 139(1)
The present study tested the hypothesis that the cytokine tumor necrosis factor-alpha (TNF-alpha) is an important central nervous system mediator of the rat hypothalamo-pituitary-adrenal (HPA) axis response to the i.v. administration of lipopolysacch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c0c316cc23f4c948a8d8579f8562dd6
https://pubmed.ncbi.nlm.nih.gov/9421406
https://pubmed.ncbi.nlm.nih.gov/9421406
Autor:
A V, Turnbull, C L, Rivier
Publikováno v:
Endocrinology. 139(1)
The findings of the preceding article suggest that intracerebroventricular (i.c.v.) administration of small amounts (5 microl) of antisera to rats may produce effectual immunoneutralization of peptides in blood/tissues outside of the central nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef686d879cb4899d5c61f5c99addf01e
https://pubmed.ncbi.nlm.nih.gov/9421407
https://pubmed.ncbi.nlm.nih.gov/9421407