Zobrazeno 1 - 10
of 13
pro vyhledávání: '"C L, Nichols"'
Autor:
S L Briggs, Hinson Na, Corvalan, C L Nichols, James J. Starling, Smith W, Maciak Rs, Bennett C. Laguzza
Publikováno v:
Bioconjugate Chemistry. 3:315-322
A panel of four murine monoclonal antibodies apparently directed against three distinct epitopes of carcinoembryonic antigen (CEA) was conjugated via oxidized carbohydrate groups to 4-desacetylvinblastine-3-carboxyhydrazide. The resulting antibody-vi
Publikováno v:
Bioconjugate chemistry. 4(6)
A new carrier molecule, NH2OCH2CO-(Gly)3-[Lys(H-Ser-)]5-Gly-OH, has been synthesized to facilitate the preparation of protein conjugates of defined structure. Special features are as follows: (i) (aminooxy)-acetyl as a terminal group, which reacts sp
Publikováno v:
Peptides 1992 ISBN: 9789401046466
Peptides 1992
Peptides 1992
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91d904e9626eaab6694e1d52f07eef6c
https://doi.org/10.1007/978-94-011-1470-7_375
https://doi.org/10.1007/978-94-011-1470-7_375
Autor:
J M, Schaus, E C, Kornfeld, R D, Titus, C L, Nichols, D L, Huser, J A, Clemens, E B, Smalstig, R W, Fuller
Publikováno v:
Drug design and discovery. 9(3-4)
Ergot alkaloids and their derivatives have long been recognized for their potent pharmacologic activity. A number of ergot derivatives, including the dopamine agonists bromocriptine and pergolide, are currently in clinical use for the treatment of CN
Autor:
C. L. Nichols
Publikováno v:
Navigation. 3:89-93
The Principality of Monaco, of which Monte-Carlo is a part, is inevitably associated in the public mind with the froth of life, as a place where it is better to be decorative than useful. Yet, despite this almost universally accepted view of Monte-Ca
Autor:
C L Nichols, Frederick Tilney
Publikováno v:
The Journal of Nervous and Mental Disease. 42:95-97
n/a
Autor:
M M, Foreman, R W, Fuller, M D, Hynes, J S, Gidda, C L, Nichols, J M, Schaus, E C, Kornfeld, J A, Clemens
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 250(1)
Quinelorane (LY163502) has the endocrine, neurochemical and behavioral profile of a potent and highly selective D2-dopaminergic agonist. The administration of quinelorane produced dose-related decreases in serum prolactin concentration of reserpinize
Autor:
George Joseph Cullinan, Bennett C. Laguzza, J. R. F. Corvalan, T. F. Bumol, C L Nichols, James J. Starling, Stephen L. Briggs, David W. Johnson, A. L. Baker
Publikováno v:
Journal of medicinal chemistry. 32(3)
A method has been developed to allow the direct coupling of the cytotoxic vinca alkaloid 4-desacetylvinblastine-3-carbohydrazide (DAVLB hydrazide) to a variety of murine monoclonal antibodies directed against human solid tumors. Periodate oxidation o
Publikováno v:
Cancer Immunology Immunotherapy. 28
A panel of three hybridomas has been isolated each of which secretes a single species of monoclonal antibody (MoAb) directed against the KS1/4 tumor-associated antigen originally described by Varki et al. (Cancer Res 44: 681, 1984). These MoAbs were
Publikováno v:
Life sciences. 38(4)
LY163502, a partial ergoline and a trans-levorotatory enantiomer, does not stimulate adenylate cyclase in striatal membranes but inhibits 50% binding of 3H-apomorphine, 3H-pergolide and 3H-spiperone at 10, 13 and 151 nM (IC50), respectively. The race