Výsledky vyhledávání - "C L, Kempton"

Pharmacokinetics and safety of OBI-1, a recombinant B domain-deleted porcine factor VIII, in subjects with haemophilia A

Autor: C L, Kempton, T C, Abshire, R A, Deveras, W K, Hoots, J C, Gill, C M, Kessler, N S, Key, B A, Konkle, P, Kuriakose, D E, Macfarlane, G, Bergman

Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia. 18(5)

OBI-1 is a recombinant B-domain deleted porcine factor VIII (FVIII). FVIII treatment in those with haemophilia A may be complicated by the development of anti-FVIII antibodies (inhibitors) leading to a failure to respond to treatment with human FVIII

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c177bdc9fb129573c7270828b96a62f
https://pubmed.ncbi.nlm.nih.gov/22512291

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Cellular immune responses in hemophilia: why do inhibitors develop in some, but not all hemophiliacs?

Autor: C. L. Kempton, Gilbert C. White, H. R. Roberts, A. Grimsley, Brenda Nielsen

Publikováno v: Journal of thrombosis and haemostasis : JTH. 3(8)

Advances in molecular immunology over the past two decades permit a better understanding of why antibodies develop to peptide antigens like factor VIII and the events that lead to the development of these antibodies. Two important variables that are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508f50f9f7bb1791279af9d8f138f0e9
https://pubmed.ncbi.nlm.nih.gov/16102033

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