Zobrazeno 1 - 10
of 64
pro vyhledávání: '"C L, Jordan"'
Autor:
M. H. Thompson, S. H. Wilson, B. L. Toussaint, C. L. Jordan, G. L. Hayes, B. P. McKinzie, B. J. Wolf, L. C. Field
Publikováno v:
Survey of Anesthesiology. 61:20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a94721cfd55acfe3b75ae9e1bf4ff065
https://doi.org/10.1097/01.sa.0000513234.63915.f6
https://doi.org/10.1097/01.sa.0000513234.63915.f6
Autor:
Mark A. Muesing, Robert Theodore Vasileff, Sahlberg C, Robert J. Ternansky, Cantrell As, C. L. Jordan, Jaskunas, L. Vrang, P. Engelhardt, Peter Thomas Lind, H. Zhang, Kinnick, R. Noreen, West Sj, Marita Högberg, Pranc P, J. Kangasmetsa, B. Oberg, N. G. Johansson, J. M. Jun. Morin
Publikováno v:
Journal of Medicinal Chemistry. 39:4261-4274
Phenylethylthiazolylthiourea (PETT) derivatives have been identified as a new series of non-nucleoside inhibitors of HIV-1 RT. Structure-activity relationship studies of this class of compounds resulted in the identification of N-[2-(2-pyridyl)ethyl]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996a50dd39f38af704f493f59146bf93
https://doi.org/10.1021/jm950639r
https://doi.org/10.1021/jm950639r
Autor:
Johansson Nils Gunnar, F W Bell, Marita Högberg, Rolf Noreen, Jaskunas, C. L. Jordan, Cantrell As, Peter Thomas Lind, J. M. Jun. Morin, Kinnick
Publikováno v:
Journal of Medicinal Chemistry. 38:4929-4936
A novel series of potent specific HIV-1 inhibitory compounds is described. The lead compound in the series, N-(2-phenethyl)-N'-(2-thiazolyl)thiourea (1), inhibits HIV-1 RT using rCdG as the template with an IC50 of 0.9 microM. In MT-4 cells, compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363d4dab7ef164ee59e046f1e8fd8e74
https://doi.org/10.1021/jm00025a010
https://doi.org/10.1021/jm00025a010
Autor:
C. L. Jordan, Robert J. Ternansky
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:2443-2446
The synthesis of 1-carba-1-dethiacephalosporin nuclei is described. The new route utilizes a readily-available penicillin derivative as starting material and features an intramolecular ring closure to form the six-membered ring.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a5e0841c985598d46fbbfc91c460a52
https://doi.org/10.1016/s0960-894x(01)80974-4
https://doi.org/10.1016/s0960-894x(01)80974-4
Autor:
R J, Ternansky, S E, Draheim, A J, Pike, F W, Bell, S J, West, C L, Jordan, C Y, Wu, D A, Preston, W, Albron, J S, Kasher
Publikováno v:
Journal of Medicinal Chemistry. 36:1971-1976
The synthesis and antimicrobial activity of several new 1-carba-1-dethiacephalosporins is described. The discovery of unique activity of some of the analogues against methicillin-resistant Staphylococcus aureus led to the development of a structure-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef233af96e7d183ab5c3b58dd175ca2
https://doi.org/10.1021/jm00066a006
https://doi.org/10.1021/jm00066a006
Autor:
Jack B. Deeter, John Michael Morin, Robert J. Ternansky, David A. Hall, Richard M. Justice, Michael Dean Kinnick, Jonathan W. Paschal, C. L. Jordan
Publikováno v:
Tetrahedron Letters. 34:3051-3054
A new method for the synthesis of chiral azetidinones bearing a carbon-carbon bond at the 4-position is described. The preparation involves a stereoselective alkylation-reduction of a silylated 4-phenylsulfonyl azetidinone. The utility of this method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15e825bf359a7d0a242f22cfc5abf775
https://doi.org/10.1016/s0040-4039(00)93376-8
https://doi.org/10.1016/s0040-4039(00)93376-8
Autor:
Walter E. Wright, William Joseph Hornback, C. Y. E. Wu, C. L. Jordan, John E. Munroe, R. J. Johnson, J. A. Eudaly
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ecc7fa3ad928fccc360558f062a2457
https://doi.org/10.1002/chin.199248313
https://doi.org/10.1002/chin.199248313
Autor:
Robert J. Ternansky, Michael Dean Kinnick, David A. Hall, Jack B. Deeter, Jonathan W. Paschal, John Michael Morin, C. L. Jordan, Richard M. Justice
Publikováno v:
ChemInform. 24
A new method for the synthesis of chiral azetidinones bearing a carbon-carbon bond at the 4-position is described. The preparation involves a stereoselective alkylation-reduction of a silylated 4-phenylsulfonyl azetidinone. The utility of this method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ee076f572aa24a0896c495693846be9
https://doi.org/10.1002/chin.199340175
https://doi.org/10.1002/chin.199340175
Publikováno v:
ChemInform. 24
The synthesis and biological evaluation of novel 1-carba-1-dethiacephalosporins exhibiting activity against anaerobic pathogens are described. The nitrothiazole substituent was determined to be crucial to maintaining this activity. The pharmacokineti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::351b782a5d2d608cb09eb264c49f7b1c
https://doi.org/10.1002/chin.199352291
https://doi.org/10.1002/chin.199352291
Autor:
L C, Blaszczak, R F, Brown, G K, Cook, W J, Hornback, R C, Hoying, J M, Indelicato, C L, Jordan, A S, Katner, M D, Kinnick, J H, McDonald
Publikováno v:
Journal of Medicinal Chemistry. 33:1656-1662
Nine matched pairs of cephalosporins and their 1-carba-1-dethiacephalosporin analogues have been compared with regard to microbiological activity, beta-lactam carbonyl infrared absorption, and aqueous stability. In general the microbiological activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ba36d4797bc6c70f30624a795860e9
https://doi.org/10.1021/jm00168a019
https://doi.org/10.1021/jm00168a019