Výsledky vyhledávání - "C L, Granvil"

Autor: C. L. Granvil, Murray P. Ducharme, M. Di Marco, Irving W. Wainer, G. Batist

Publikováno v: Pharmaceutical Research. 17:645-652

Purpose. To describe the pharmacokinetics of R- andS-Ifosfamide (IFF), and their respective 2 and 3 N-dechloroethylated (DCE)metabolites (R2-, R3-, S2, S3-DCE-IFF) in cancer patients.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5db43b2d8d96e88239b684fcc7f61a70
https://doi.org/10.1023/a:1007561727948

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New insights into the pharmacokinetics and metabolism of (R,S)-ifosfamide in cancer patients using a population pharmacokinetic-metabolism model

Autor: M P, Di Marco, I W, Wainer, C L, Granvil, G, Batist, M P, Ducharme

Publikováno v: Pharmaceutical research. 17(6)

To describe the pharmacokinetics of R- and S-Ifosfamide (IFF), and their respective 2 and 3 N-dechloroethylated (DCE) metabolites (R2-, R3-, S2, S3-DCE-IFF) in cancer patients.(R,S)-IFF was administered (1.5 g/m2) daily for 5 days in 13 cancer patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b6104dcff22c34a62f774ea4b0de647
https://pubmed.ncbi.nlm.nih.gov/10955835

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Enantioselective induction of cyclophosphamide metabolism by phenytoin

Autor: M L, Williams, I W, Wainer, L, Embree, M, Barnett, C L, Granvil, M P, Ducharme

Publikováno v: Chirality. 11(7)

The objective of this study was to investigate the effect of phenytoin (PHE) on cyclophosphamide (CP) disposition. CP was administered to 6 adult patients in a preparative regimen for bone marrow transplantation consisting of busulfan and CP. Three o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d734e1311f078db02fbda932bf70984c
https://pubmed.ncbi.nlm.nih.gov/10423284

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