Zobrazeno 1 - 8
of 8
pro vyhledávání: '"C L, Baum"'
Publikováno v:
Krankenhaushygiene up2date. 11:335-336
Publikováno v:
Endocrinology. 131:1125-1133
We have examined the effects of 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] on the phosphoinositol signal transduction pathway in the human colon cancer-derived cell line CaCo-2 and have studied the regulation of intracellular calcium ([Ca2+]i) and pH (p
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 5, Pp 729-739 (1993)
Sterol carrier protein-2 (SCP2) is a peroxisomal protein most highly expressed in non-steroidogenic tissues such as liver and small intestine. We have examined SCP2 gene expression during development and after alterations in lipid and bile acid metab
Publikováno v:
The Journal of biological chemistry. 265(31)
Apolipoprotein B (apoB) mRNA is modified by a posttranscriptional editing reaction in which a single base (C to U) change in apoB100 mRNA modifies a glutamine (CAA) to a translational stop codon (UAA), producing apoB48 mRNA in mammalian intestine. Ra
Publikováno v:
Cancer research. 50(13)
Recently, a number of studies in experimental animals and humans have suggested that alterations in the activity of protein kinase C (PKC) may be involved in the malignant transformation process. To determine whether such alterations in this kinase w
Publikováno v:
Clinical Pharmacology & Therapeutics. 75:P95
Water-soluble vitamin E(D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) may increase oral drug absorption. In vitro and animal data suggest that TPGS inhibits P-gp. It is unknown whether α-tocopherol acetate(TA), the more common formulatio
Publikováno v:
Clinical Pharmacology & Therapeutics. 75:P31
Although human hepatocytes usually provide an accurate estimate of drug metabolism in vivo, oral CLZ appears to induce CYP3A4 in vitro and inhibit CYP3A4 in vivo. This discrepancy indicates that predicting the effect of a drug on CYP activity in vivo
Publikováno v:
The Journal of laboratory and clinical medicine. 97(6)
SASP, the drug most widely used for the treatment of Crohn's disease and ulcerative colitis, is a competitive inhibitor of intestinal folate metabolism and transport. Some of the therapeutic effects of the drug could be related to antifolate actions