Zobrazeno 1 - 10
of 28
pro vyhledávání: '"C Kletke"'
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 12, Pp 2063-2075 (1993)
The mass isotopomer distribution analysis (MIDA) technique is applied here in men and menstruating women to quantify periodicities in the biosynthesis of serum cholesterol and very low density lipoprotein (VLDL)-palmitate. The isotopic enrichment of
Externí odkaz:
https://doaj.org/article/6d13c4a6e74a4a59bbdafa28d346a242
Autor:
Richard A. Neese, S. Wolden, Marc K. Hellerstein, D. Faix, C. Kletke, Cedric H.L. Shackleton, Denise Cesar, M. Coutlangus
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 12, Pp 2063-2075 (1993)
The mass isotopomer distribution analysis (MIDA) technique is applied here in men and menstruating women to quantify periodicities in the biosynthesis of serum cholesterol and very low density lipoprotein (VLDL)-palmitate. The isotopic enrichment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd0eea385a75a90594ddc40fe96505f
https://doi.org/10.1016/s0022-2275(20)35348-7
https://doi.org/10.1016/s0022-2275(20)35348-7
Publikováno v:
Journal of Biological Chemistry. 266:10912-10919
The acetylation of xenobiotics may provide a means for sampling hepatic cytosolic acetyl-CoA in vivo for isotopic studies of lipogenesis. Here, we test the accuracy of acetylated-sulfamethoxazole (SMX) in representing the true precursor pool for hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa78ad272ae030b299fdcc86bb818c0
https://doi.org/10.1016/s0021-9258(18)99106-4
https://doi.org/10.1016/s0021-9258(18)99106-4
Autor:
M. Christiansen, C. Kletke, J. S. Reid, Kathleen Mulligan, Marc K. Hellerstein, K. Wu, S. Kaempfer, Cedric H.L. Shackleton, N. S. Hellerstein
Publikováno v:
Journal of Clinical Investigation. 87:1841-1852
Direct measurement of de novo lipogenesis has not previously been possible in humans. We measured de novo hepatic lipogenesis in normal men by means of stable isotopes and by combining the acetylated-xenobiotic probe technique with mass isotopomer an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43d488e055871ea84f5cd26d80aff8e
https://doi.org/10.1172/jci115206
https://doi.org/10.1172/jci115206
Publikováno v:
Steroids. 55:472-478
A thermospray high-performance liquid chromatography/mass spectrometry method for determination of serum dehydroepiandrosterone sulfate is described. The steroid was measured intact using [7,7-2H2]dehydroepiandrosterone sulfate as internal standard.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bdde10e722244f95b7772633a29f40
https://doi.org/10.1016/0039-128x(90)90016-5
https://doi.org/10.1016/0039-128x(90)90016-5
Autor:
J. Cone, K Yamanishi, J. A. Wilkins, Z. I. Randhawa, P Hughes, Y Masui, H. E. Witkowska, P Arthur, S Yasuda, C Kletke
Publikováno v:
Biochemistry. 33(14)
Expression of the 17.5-kDa truncated form of human recombinant macrophage colony stimulating factor (rM-CSF, 4-153) in Escherichia coli is complicated by the replacement of methionine residues by norleucine. In order to detect and quantitate this mis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9ebcaf83b17d24a5942f3755d5fa46
https://pubmed.ncbi.nlm.nih.gov/8155653
https://pubmed.ncbi.nlm.nih.gov/8155653
Autor:
C. H. L. Shackleton, C. Kletke, A. C. Wang, K. Wu, Marc K. Hellerstein, Richard A. Neese, D. Faix
Publikováno v:
The American journal of physiology. 264(1 Pt 1)
We used the mass isotopomer distribution analysis (MIDA) technique to measure endogenous synthesis of plasma cholesterol in vivo in rats and normal human subjects. Sodium [1-13C]- or [2-13C]acetate was infused, and plasma free cholesterol was analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921aaf5da04823404eaae7e28db78063
https://pubmed.ncbi.nlm.nih.gov/8430782
https://pubmed.ncbi.nlm.nih.gov/8430782
Publikováno v:
The American journal of physiology. 261(4 Pt 1)
Measurement of hepatic fatty acid (FA) and cholesterol synthesis has been limited by lack of access to the precursor pool, cytosolic acetyl-CoA. We present a method for inferring the enrichment of the true hepatic lipogenic precursor pool in humans u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaf6fd0aadd34971860692cc6e270eb
https://pubmed.ncbi.nlm.nih.gov/1928339
https://pubmed.ncbi.nlm.nih.gov/1928339
Publikováno v:
The Journal of biological chemistry. 266(17)
The acetylation of xenobiotics may provide a means for sampling hepatic cytosolic acetyl-CoA in vivo for isotopic studies of lipogenesis. Here, we test the accuracy of acetylated-sulfamethoxazole (SMX) in representing the true precursor pool for hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1dd7581bbbe6f64f2ad58ac67634341
https://pubmed.ncbi.nlm.nih.gov/2040608
https://pubmed.ncbi.nlm.nih.gov/2040608
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