Zobrazeno 1 - 10
of 14
pro vyhledávání: '"C K Derian"'
Publikováno v:
Biochemistry (Moscow). 67:56-64
The serine protease thrombin is well recognized as being pivotal to the maintenance of hemostasis under both normal and pathological conditions. Its cellular actions are mediated through a unique family of protease-activated receptors (PARs). These r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e63c211eacad8afb5cc3b2b375b5623
https://doi.org/10.1023/a:1013900130415
https://doi.org/10.1023/a:1013900130415
Publikováno v:
The Journal of Immunology. 154:308-317
An early event associated with neutrophil-dependent tissue damage involves the adhesion of neutrophils to the vascular endothelium and the subsequent release of oxygen-derived free radicals and granule constituents. Elevations in intracellular cAMP a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ed81dd5b8cec73d90fd289bde5defb5
https://doi.org/10.4049/jimmunol.154.1.308
https://doi.org/10.4049/jimmunol.154.1.308
Publikováno v:
Biochemistry. Biokhimiia. 67(1)
The serine protease thrombin is well recognized as being pivotal to the maintenance of hemostasis under both normal and pathological conditions. Its cellular actions are mediated through a unique family of protease-activated receptors (PARs). These r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89d530f43c01bd56274bcb2aa26e6fdd
https://pubmed.ncbi.nlm.nih.gov/11841340
https://pubmed.ncbi.nlm.nih.gov/11841340
Autor:
J T, Elliott, W J, Hoekstra, C K, Derian, M F, Addo, B E, Maryanoff, D G, Ahern, G D, Prestwich
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 57(6)
Six photoactivatable analogs of the human thrombin receptor activating peptide (TRAP), SFLLRN-NH2, were synthesized by substituting the photoactive amino acid, p-benzoylphenylalanine (Bpa), into each position of the peptide sequence. Platelet aggrega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29f1177a725f0ef58f3a873d8afc2862
https://pubmed.ncbi.nlm.nih.gov/11437953
https://pubmed.ncbi.nlm.nih.gov/11437953
Autor:
P, Andrade-Gordon, C K, Derian, B E, Maryanoff, H C, Zhang, M F, Addo, Cheung Wm, B P, Damiano, M R, D'Andrea, A L, Darrow, L, de Garavilla, A J, Eckardt, E C, Giardino, B J, Haertlein, D F, McComsey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(1)
Human platelets possess two distinct thrombin-activated receptors, PAR-1 (protease-activated receptor-1) and PAR-4, whereas human vascular smooth muscle cells possess only PAR-1. Although such thrombin receptors have been studied extensively in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18a00983bda7a1b6bd81fc0953668bf9
https://pubmed.ncbi.nlm.nih.gov/11408522
https://pubmed.ncbi.nlm.nih.gov/11408522
Publikováno v:
Canadian journal of physiology and pharmacology. 76(1)
Vascular expression and cellular functions of the thrombin receptor (PAR-1) and protease activated receptor 2 (PAR-2) suggest similar but distinct vascular regulatory roles. The vascular actions of PAR-1 and PAR-2 in vivo were differentiated by monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cd9253a4438ede8206439b725b70d9f
https://pubmed.ncbi.nlm.nih.gov/9564545
https://pubmed.ncbi.nlm.nih.gov/9564545
Publikováno v:
Blood. 90(10)
The proteinase-activated receptor-2 (PAR-2) is the second member of a putative larger class of proteolytically activated receptors that mediate cell activation events by receptor cleavage or synthetic peptidomimetics corresponding to the newly genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f1e524c08508a3ab95cfacb162138da
https://pubmed.ncbi.nlm.nih.gov/9354658
https://pubmed.ncbi.nlm.nih.gov/9354658
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(7)
Thrombin receptor (ThrR) and protease-activated receptor-2 (PAR-2) are members of a unique G protein-coupled receptor family, which are characterized by the unveiling of a tethered peptide ligand upon proteolysis of their NH2 terminus. We have previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5caca33175cf3d327538732d610e889f
https://pubmed.ncbi.nlm.nih.gov/9218868
https://pubmed.ncbi.nlm.nih.gov/9218868
Autor:
C K Derian, Michael A. Moskowitz
Publikováno v:
Journal of Biological Chemistry. 261:3831-3837
Bovine aortic and cerebral microvascular endothelial cells and cultured segments of canine common carotid artery possess functional receptors for the nonapeptide bradykinin which mediate a rapid increase in the formation of [3H]inositol 1-phosphate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79ce4de20ca4673b8c424ee0c7b47275
https://doi.org/10.1016/s0021-9258(17)35722-8
https://doi.org/10.1016/s0021-9258(17)35722-8
Publikováno v:
Biochemical and biophysical research communications. 94(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11c3f3d83faf3afc3778f27ec5a611d2
https://pubmed.ncbi.nlm.nih.gov/7396938
https://pubmed.ncbi.nlm.nih.gov/7396938