Zobrazeno 1 - 10
of 277
pro vyhledávání: '"C K, Lau"'
Autor:
Jahanara Rajwani, Daniil Vishnevskiy, Madison Turk, Victor Naumenko, Chris Gafuik, Dae-Sun Kim, Laura K. Mah, Shannon Snelling, Gerone A. Gonzales, Jingna Xue, Ayan Chanda, Kyle G. Potts, Hayley M. Todesco, Keith C. K. Lau, Karys M. Hildebrand, Jennifer A. Chan, Shan Liao, Michael J. Monument, Martin Hyrcza, Pinaki Bose, Craig N. Jenne, Johnathan Canton, Franz J. Zemp, Douglas J. Mahoney
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Oncolytic viruses (OV) are designed to selectively infect and kill cancer cells, while simultaneously eliciting antitumour immunity. The mechanism is expected to originate from infected cancer cells. However, recent reports of tumour regress
Externí odkaz:
https://doaj.org/article/e1b4ff19dd154ae59c5ddb76c77964d0
Autor:
Danny Morick, Nadav Davidovich, Ziv Zemah-Shamir, Eyal Bigal, Assaf Rokney, Merav Ron, Shlomo E. Blum, Marcelo Fleker, Esteban Soto, Taylor I. Heckman, Stanley C. K. Lau, Natascha Wosnick, Dan Tchernov, Aviad P. Scheinin
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
Streptococcosis is an infectious bacterial disease of both homeotherms and poikilotherms. Among the Streptococcus species that infect marine animals, Streptococcus agalactiae has the broadest host spectrum, including different aquatic organisms in fr
Externí odkaz:
https://doaj.org/article/515464e2542c42ee88bcea1f1892b6a1
Autor:
Keith C. K. Lau, Shivali S. Joshi, Douglas J. Mahoney, Andrew L. Mason, Guido van Marle, Carla Osiowy, Carla S. Coffin
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
BackgroundChronic hepatitis B virus (HBV) infection is the leading cause of hepatocellular carcinoma (HCC) world-wide. HBV variants, particularly the G1896A pre-core (PC) and A1762T/G1764A basal core promoter (BCP) mutations, are established risk fac
Externí odkaz:
https://doaj.org/article/e29188ca93214241ac4a7e09fd153aae
Autor:
Saw-Lin Oo, Shishir Venkatesh, Vaithinathan Karthikeyan, Clement Manohar Arava, Spoorthy Pathikonda, Peter K. N. Yu, Terrence C. K. Lau, Xianfeng Chen, Vellaisamy A. L. Roy
Publikováno v:
Sensors, Vol 21, Iss 8, p 2639 (2021)
Facile and efficient early detection of cancer is a major challenge in healthcare. Herein we developed a novel sensor made from a polycarbonate (PC) membrane with nanopores, followed by sequence-specific Oligo RNA modification for early gastric carci
Externí odkaz:
https://doaj.org/article/8ede0a0c84574f18a88af064ae37f72a
Publikováno v:
Microorganisms, Vol 8, Iss 11, p 1713 (2020)
The evolution, habitat, and lifestyle of the cryptic clade II of Escherichia, which were first recovered at low frequency from non-human hosts and later from external environments, were poorly understood. Here, the genomes of selected strains were an
Externí odkaz:
https://doaj.org/article/a8107bd50e494fc6ab9053354d29ec8d
Autor:
Yael Regev, Nadav Davidovich, Ran Berzak, Stanley C. K. Lau, Aviad P. Scheinin, Dan Tchernov, Danny Morick
Publikováno v:
Microorganisms, Vol 8, Iss 8, p 1153 (2020)
We would like to change the authors’ affiliation of paper [...]
Externí odkaz:
https://doaj.org/article/c6d551a7e108420386c06100a561475b
Autor:
Yael Regev, Nadav Davidovich, Ran Berzak, Stanley C. K. Lau, Aviad P. Scheinin, Dan Tchernov, Danny Morick
Publikováno v:
Microorganisms, Vol 8, Iss 6, p 863 (2020)
In contrast to numerous documented pathogens and infectious diseases of aquaculture, there is a lack of baseline data and information regarding pathogenic agents’ prevalence in wild marine fish populations. This study focused on two common fish pat
Externí odkaz:
https://doaj.org/article/86e4cd763e3e43af8c82b0f88b0fbcba
Autor:
Hoi-Kuan Kong, Xuan Liu, Wai U. Lo, Qing Pan, Carmen O. K. Law, Ting F. Chan, Pak L. Ho, Terrence C. K. Lau
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Small RNAs (sRNAs) play significant roles in regulating gene expression post-transcriptionally in response to environmental changes in bacteria. In this work, we identified and characterized six novel sRNAs from an emerging multidrug-resistance (MDR)
Externí odkaz:
https://doaj.org/article/7b250cdf88884828b28f742f029af841
Publikováno v:
Journal of Bioscience and Bioengineering. 132:621-629
Cyclohexanecarboxylate (CHCA) is formed by oxidative microbial degradation of n-alkylcycloparaffins and anaerobic degradation of benzoate, and also known to be a synthetic intermediate or the starter unit of biosynthesis of cellular constituents and
Autor:
Ian C-K Lau, Joel H. Z. Lee, John B. Bruning, James J. De Voss, Rebecca R. Chao, Stephen Bell, T. Coleman, Stella A. Child, Luke R. Churchman
Publikováno v:
Chemistry – A European Journal. 27:14765-14777
The serine 244 to aspartate (S244D) variant of the cytochrome P450 enzyme CYP199A4 was used to expand its substrate range beyond benzoic acids. Substrates, in which the carboxylate group of the benzoic acid moiety is replaced were oxidised with high