Zobrazeno 1 - 8
of 8
pro vyhledávání: '"C K, Hiebert"'
Autor:
I Uchida, Smith Rl, A K Judd, C K Hiebert, R G Almquist, Waud Wr, Dousman L, Joseph I. DeGraw
Publikováno v:
Journal of Medicinal Chemistry. 40:2398-2406
In this second paper in a series of three studies of stable analogs of thymopentin (Arg1-Lys2-Asp3-Val4-Tyr5), the synthesis of analogs stabilized at peptide bonds 1,2 and 3,4 via insertion of ketomethylene units is described. A tris(carbobenzyloxy)a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90188d4bac5df077db3b1094584a911
https://doi.org/10.1021/jm9508043
https://doi.org/10.1021/jm9508043
Autor:
Dousman L, I Uchida, A K Judd, J Crase, C K Hiebert, R G Almquist, W. T. Colwell, Waud Wr, T. Hayano, Smith Rl, Joseph I. DeGraw
Publikováno v:
Journal of medicinal chemistry. 40(15)
The pentapeptide, thymopentin (Arg1-Lys2-Asp3-Val4-Tyr5) is known for its activity as an immunomodulating drug, but with limited half-life in plasma. In this first paper of a series of three studies, the synthesis of analogs stabilized at the peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27e7129bebbb799087e79b755c8795f
https://pubmed.ncbi.nlm.nih.gov/9240353
https://pubmed.ncbi.nlm.nih.gov/9240353
Publikováno v:
Chemischer Informationsdienst. 15
A fluorescent-labeled muramyl dipeptide (MDP) has been prepared to probe immunoadjuvant cellular interactions. N-Acetylmuramyl-L-alanyl-D-isoglutamine (1) was synthesized in improved yield and reacted with 2-(fluoresceinylamino)-4,6-dichloro-s-triazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d5ec3bc472499f70c57bc8a553f89df
https://doi.org/10.1002/chin.198418333
https://doi.org/10.1002/chin.198418333
Publikováno v:
Journal of medicinal chemistry. 31(10)
Muramyl dipeptide (MDP) analogues were prepared and utilized in the synthesis of new fluorescently labeled MDP derivatives for use as biologic probes. Thus, N alpha-(N-acetylmuramyl)-L-lysyl-D-isoglutamine (Lys-MDP, 4) and N alpha-(N-acetylmuramyl)-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d566cf4fe36dcf8d598737bdfb0292
https://pubmed.ncbi.nlm.nih.gov/3172138
https://pubmed.ncbi.nlm.nih.gov/3172138
Publikováno v:
The Journal of biological chemistry. 264(36)
It was previously shown (Sayre, L. M., Arora, P. K., Feke, S. C., and Urbach, F. L. (1986) J. Am. Chem. Soc. 108, 2464-2466) that 1,3,3-trimethyl-4-phenyl-2,3-dihydropyridinium salt (the 3,3-dimethyl analogue of 1-methyl-4-phenyl-2,3-dihydropyridiniu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6d832aa0f518ca275d5bfbaa4c2c0f0
https://pubmed.ncbi.nlm.nih.gov/2600079
https://pubmed.ncbi.nlm.nih.gov/2600079
Publikováno v:
Journal of medicinal chemistry. 26(12)
A fluorescent-labeled muramyl dipeptide (MDP) has been prepared to probe immunoadjuvant cellular interactions. N-Acetylmuramyl-L-alanyl-D-isoglutamine (1) was synthesized in improved yield and reacted with 2-(fluoresceinylamino)-4,6-dichloro-s-triazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1607b599490fef01b613bd8a632c9235
https://pubmed.ncbi.nlm.nih.gov/6644742
https://pubmed.ncbi.nlm.nih.gov/6644742
Publikováno v:
The Journal of biological chemistry. 260(27)
[1-3H]Allylamine was synthesized by sodium boro[3H]hydride reduction of acrolein followed by direct conversion of the [1-3H]allyl alcohol to N-allylphthalimide with triphenylphosphine, diethylazodicarboxylate, and phthalimide. The protecting group wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59e7192cc7625ddf34a9d8d76d851866
https://pubmed.ncbi.nlm.nih.gov/4055794
https://pubmed.ncbi.nlm.nih.gov/4055794
Autor:
Michael T. Suelzer, P.A. Swanson, C.K. Barfknecht, C. K. Hiebert, John E. Butler, William C. Kopp, Hal B. Richerson
Publikováno v:
Journal of Allergy and Clinical Immunology. 69:107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a448a874cd2afcc3acf78179d65e9625
https://doi.org/10.1016/s0091-6749(62)80342-x
https://doi.org/10.1016/s0091-6749(62)80342-x