Zobrazeno 1 - 10
of 74
pro vyhledávání: '"C K, Grieshaber"'
Autor:
C K Grieshaber, Brian Leyland-Jones
Publikováno v:
British Journal of Cancer. 81:753-755
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b740448e61a17b1671422ce4960b9c9
https://doi.org/10.1038/sj.bjc.6690759
https://doi.org/10.1038/sj.bjc.6690759
Publikováno v:
Experimental hematology. 18(7)
Three nucleoside analogues, 2',3'-dideoxyadenosine (ddA), 2',3'-dideoxyinosine (ddI), and 2',3'-dideoxycytosine (ddC), were evaluated for their potential myelotoxic effects to normal human hematopoietic progenitor cells. The myeloid (granulocyte-mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7eb3f135fbac55e6abe486500b1811fd
https://pubmed.ncbi.nlm.nih.gov/2379548
https://pubmed.ncbi.nlm.nih.gov/2379548
Publikováno v:
Cancer research. 50(13)
The effects of L-buthionine sulfoximine (L-BSO) and L-phenylalanine mustard (L-PAM), alone and in combination, on human and murine marrow were explored using in vitro clonogenic assays to establish whether enhanced myelotoxicity might limit the clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::176dd186fe51c233119b057fd45aa373
https://pubmed.ncbi.nlm.nih.gov/2354454
https://pubmed.ncbi.nlm.nih.gov/2354454
Publikováno v:
Journal of Clinical Oncology. 23:2065-2065
2065 Background: Amonafide malate (Xanafide, Xan) is currently under study in AIPC as an individualized therapy based on the rate of Xan conversion to its N-acetyl metabolite by NAT-2. The current ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b66bd5b543e8bac2343e65dcb6bea34
https://doi.org/10.1200/jco.2005.23.16_suppl.2065
https://doi.org/10.1200/jco.2005.23.16_suppl.2065
Autor:
R. Dubon, M. Drouin, C. K. Grieshaber, Jonathan E. Kolitz, M. A. Boss, M. Champagne, Steven L. Allen, Daniel R. Budman, Ante Sven Lundberg, S. Devost
Publikováno v:
Journal of Clinical Oncology. 23:6602-6602
6602 Background: Amonafide (Am) is an ATP independent topoisomerase 2 inhibitor that in prior clinical studies demonstrated activity in breast cancer (18–25% response rate (RR)) and prostate cancer...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5baee6deec7a79f21a28ff9cf26d7a83
https://doi.org/10.1200/jco.2005.23.16_suppl.6602
https://doi.org/10.1200/jco.2005.23.16_suppl.6602
Publikováno v:
Blood. 51:1021-1029
Enriched fractions of mature and immature neutrophil granulocytes, isolated from guinea pig bone marrow, were assayed for ornithine decarboxylase activity and polyamine content. The results show that immature granulocytes contain at least ten times m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d44bb9734845debff076f5f327961b
https://doi.org/10.1182/blood.v51.6.1021.bloodjournal5161021
https://doi.org/10.1182/blood.v51.6.1021.bloodjournal5161021
Autor:
W. C. Hymer, C. K. Grieshaber
Publikováno v:
Experimental Biology and Medicine. 128:459-463
Summary1. Evidence obtained by radio-autography and sucrose density gradient centrifugation indicated that macromolecular RNA was synthesized in explants of rat anterior pituitary tissue in vitro. 2. The rapidly labeled RNA was, in part, heavier than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb972b68e8697225fac9f02e4663dd7d
https://doi.org/10.3181/00379727-128-33037
https://doi.org/10.3181/00379727-128-33037
Autor:
A C, Smith, D, Barrett, M A, Stedham, M, el-Hawari, M D, Kastello, C K, Grieshaber, M R, Boyd
Publikováno v:
Cancer treatment reports. 71(12)
4-Ipomeanol (ipomeanol) is being developed as a potential antitumor agent to treat lung cancer. Ipomeanol produced a dose-related toxicity in CD2F1 mice, Fischer 344 rats, and beagle dogs. The LD50 in mice after a single iv dose of ipomeanol was 35 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d73a1d36a95d4c16283837f69979ea0
https://pubmed.ncbi.nlm.nih.gov/3690525
https://pubmed.ncbi.nlm.nih.gov/3690525
Autor:
H A, Hoffman, C K, Grieshaber
Publikováno v:
The Journal of heredity. 65(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d63b145f3ef1992e02fd34f2d183b5b
https://pubmed.ncbi.nlm.nih.gov/4436533
https://pubmed.ncbi.nlm.nih.gov/4436533
Autor:
C K, Grieshaber, S, Marsoni
Publikováno v:
Cancer treatment reports. 70(1)
The evolution of the Division of Cancer Treatment's preclinical toxicology protocols over the last decade, a description of the current protocol, and the progress of this protocol regarding quantitative and qualitative relationships to current clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05d610d3a4db2c489d76aa36c0db6aa8
https://pubmed.ncbi.nlm.nih.gov/3943115
https://pubmed.ncbi.nlm.nih.gov/3943115