Zobrazeno 1 - 10
of 35
pro vyhledávání: '"C K, Atterwill"'
Publikováno v:
Cell biology and toxicology. 15(3)
Rat whole-brain spheroids were used to assess the intrinsic neurotoxicity of methylenedioxy-methamphetamine (MDMA, Ecstasy) and two of its metabolites, dihydroxymethamphetamine (DHMA) and 6-hydroxy-MDMA (6-OH MDMA). Exposure of brain spheroids to MDM
Publikováno v:
Neurotoxicology. 17(3-4)
Glutamine synthetase (GS) is a key enzyme involved in glutamate compartmentalisation which may be pivotal in the course of both central free-radical mediated and excitotoxic events. The ability of the oxidants FeCl2 and H2O2 and the excitatory amino
Autor:
C K, Atterwill
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 43
Autor:
C. K. Atterwill
Publikováno v:
Journal of Neurochemistry. 35:729-734
Repeated electroconvulsive shock (ECS) administered on alternate days for 10 days produced no changes in rat striatal [3H]spiroperidol binding measured 24 h after the last shock compared to anaesthetised controls. Similarly, there was no change in wh
Publikováno v:
Neuropathology and Applied Neurobiology. 12:577-592
The effects of thyroid hormone on neural development in vitro were studied using rat fetal forebrain aggregating cultures. They were examined morphologically after growth for 21 days in medium containing fetal calf serum (S+), in a chemically defined
Autor:
C K Atterwill, A K Prince
Publikováno v:
British Journal of Pharmacology. 61:111P-159P
Publikováno v:
Journal of Neural Transmission. 60:295-302
Clonidine-induced hypoactivity was studied in rats made neonatally hypo- and hyperthyroid (PTU or T4 administered between 1-27 days postnatally) as an indication of central presynaptic alpha 2-adrenoceptor function. Paradoxically, at 28 days postnata
Publikováno v:
Journal of Neurochemistry. 31:1027-1033
Rats treated with reserpine show increased Vmax for the high affinity uptake of choline into small slices of corpus striatum. The choline acetyltransferase activity of whole homogenates of striatum is also increased. These changes are consistent with
Autor:
A. K. Prince, C. K. Atterwill
Publikováno v:
Journal of Neurochemistry. 31:719-725
— The multiple molecular forms of choline acetyltransferase (ChAT) were analysed during the postnatal development of rat brain. Changes in the sodium-dependent, high affinity uptake of [3H]choline (HAUC) and in the efficiency of conversion of label