Zobrazeno 1 - 10
of 58
pro vyhledávání: '"C Joel McManus"'
Autor:
Max V Cravener, Eunsoo Do, Gemma May, Robert Zarnowski, David R Andes, C Joel McManus, Aaron P Mitchell
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011109 (2023)
Biofilms of the fungal pathogen Candida albicans include abundant long filaments called hyphae. These cells express hypha-associated genes, which specify diverse virulence functions including surface adhesins that ensure biofilm integrity. Biofilm fo
Externí odkaz:
https://doaj.org/article/86426b14307945c08c01ad98f2b51576
Autor:
Katherine Lagree, Carol A Woolford, Manning Y Huang, Gemma May, C Joel McManus, Norma V Solis, Scott G Filler, Aaron P Mitchell
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008582 (2020)
Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way that C. albicans controls its metabolism is through the glucose repression pathway, where ex
Externí odkaz:
https://doaj.org/article/afb4094d8aa24a9a8acc436b456440d7
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007787 (2019)
Genotype-phenotype relationships can vary extensively among members of a species. One cause of this variation is circuit diversification, the alteration of gene regulatory relationships among members of a species. Circuit diversification is thought t
Externí odkaz:
https://doaj.org/article/9053167b48754a72b747454e87ce545d
Autor:
Karen K Klyczek, J Alfred Bonilla, Deborah Jacobs-Sera, Tamarah L Adair, Patricia Afram, Katherine G Allen, Megan L Archambault, Rahat M Aziz, Filippa G Bagnasco, Sarah L Ball, Natalie A Barrett, Robert C Benjamin, Christopher J Blasi, Katherine Borst, Mary A Braun, Haley Broomell, Conner B Brown, Zachary S Brynell, Ashley B Bue, Sydney O Burke, William Casazza, Julia A Cautela, Kevin Chen, Nitish S Chimalakonda, Dylan Chudoff, Jade A Connor, Trevor S Cross, Kyra N Curtis, Jessica A Dahlke, Bethany M Deaton, Sarah J Degroote, Danielle M DeNigris, Katherine C DeRuff, Milan Dolan, David Dunbar, Marisa S Egan, Daniel R Evans, Abby K Fahnestock, Amal Farooq, Garrett Finn, Christopher R Fratus, Bobby L Gaffney, Rebecca A Garlena, Kelly E Garrigan, Bryan C Gibbon, Michael A Goedde, Carlos A Guerrero Bustamante, Melinda Harrison, Megan C Hartwell, Emily L Heckman, Jennifer Huang, Lee E Hughes, Kathryn M Hyduchak, Aswathi E Jacob, Machika Kaku, Allen W Karstens, Margaret A Kenna, Susheel Khetarpal, Rodney A King, Amanda L Kobokovich, Hannah Kolev, Sai A Konde, Elizabeth Kriese, Morgan E Lamey, Carter N Lantz, Jonathan S Lapin, Temiloluwa O Lawson, In Young Lee, Scott M Lee, Julia Y Lee-Soety, Emily M Lehmann, Shawn C London, A Javier Lopez, Kelly C Lynch, Catherine M Mageeney, Tetyana Martynyuk, Kevin J Mathew, Travis N Mavrich, Christopher M McDaniel, Hannah McDonald, C Joel McManus, Jessica E Medrano, Francis E Mele, Jennifer E Menninger, Sierra N Miller, Josephine E Minick, Courtney T Nabua, Caroline K Napoli, Martha Nkangabwa, Elizabeth A Oates, Cassandra T Ott, Sarah K Pellerino, William J Pinamont, Ross T Pirnie, Marie C Pizzorno, Emilee J Plautz, Welkin H Pope, Katelyn M Pruett, Gabbi Rickstrew, Patrick A Rimple, Claire A Rinehart, Kayla M Robinson, Victoria A Rose, Daniel A Russell, Amelia M Schick, Julia Schlossman, Victoria M Schneider, Chloe A Sells, Jeremy W Sieker, Morgan P Silva, Marissa M Silvi, Stephanie E Simon, Amanda K Staples, Isabelle L Steed, Emily L Stowe, Noah A Stueven, Porter T Swartz, Emma A Sweet, Abigail T Sweetman, Corrina Tender, Katrina Terry, Chrystal Thomas, Daniel S Thomas, Allison R Thompson, Lorianna Vanderveen, Rohan Varma, Hannah L Vaught, Quynh D Vo, Zachary T Vonberg, Vassie C Ware, Yasmene M Warrad, Kaitlyn E Wathen, Jonathan L Weinstein, Jacqueline F Wyper, Jakob R Yankauskas, Christine Zhang, Graham F Hatfull
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180517 (2017)
The vast bacteriophage population harbors an immense reservoir of genetic information. Almost 2000 phage genomes have been sequenced from phages infecting hosts in the phylum Actinobacteria, and analysis of these genomes reveals substantial diversity
Externí odkaz:
https://doaj.org/article/65e7a5f405dc48c78507210f321a40e9
Autor:
Ashley R. Brown, Grant A. Fox, Irene M. Kaplow, Alyssa J. Lawler, BaDoi N. Phan, Morgan E. Wirthlin, Easwaran Ramamurthy, Gemma E. May, Ziheng Chen, Qiao Su, C. Joel McManus, Andreas R. Pfenning
Genetic studies are rapidly identifying non-protein-coding human disease-associated loci. Understanding the regulatory mechanisms underlying these loci remains a challenge because the causal variants and the tissues in which they act are often unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20d3fd569187d296363d78bc2809699e
https://doi.org/10.1101/2022.11.23.517755
https://doi.org/10.1101/2022.11.23.517755
Publikováno v:
mBio. 13
Candida albicans is among the most significant human fungal pathogens. However, the vast majority of C. albicans studies have focused on a single clinical isolate and its marked derivatives. We investigated natural variation among clinical C. albican
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Hyperconserved genomic sequences have great promise for understanding core biological processes. It has been recently proposed that scores of hyperconserved 5′ untranslated regions (UTRs), also known as transcript leaders (hTLs), encode internal ri
Autor:
Gemma E. May, C. Joel McManus
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071619742
Methods in Molecular Biology ISBN: 9781071619742
Protein synthesis is a highly regulated essential process. As such, it is subjected to substantial regulation in response to stress. One hallmark of the Integrated Stress Response (ISR) is the immediate shutdown of most translation through phosphoryl
Autor:
Gemma E. May, C. Joel McManus
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071618509
Methods in Molecular Biology ISBN: 9781071618509
Eukaryotic upstream Open Reading Frames (uORFs) are short translated regions found in many transcript leaders (Barbosa et al. PLoS Genet 9:e1003529, 2013; Zhang et al. Trends Biochem Sci 44:782-794, 2019). Modern transcript annotations and ribosome p
Autor:
Hunter Kready, Yizhu Lin, Lauren Nazzaro, Yehuda Creeger, Gemma E. May, Mao Mao, C. Joel McManus, Pieter Spealman
Publikováno v:
Nucleic Acids Research
Translation regulation plays an important role in eukaryotic gene expression. Upstream open reading frames (uORFs) are potent regulatory elements located in 5′ mRNA transcript leaders. Translation of uORFs usually inhibit the translation of downstr