Reinforcement amid genetic diversity in the Candida albicans biofilm regulatory network.

Autor: Max V Cravener, Eunsoo Do, Gemma May, Robert Zarnowski, David R Andes, C Joel McManus, Aaron P Mitchell

Publikováno v: PLoS Pathogens, Vol 19, Iss 1, p e1011109 (2023)

Biofilms of the fungal pathogen Candida albicans include abundant long filaments called hyphae. These cells express hypha-associated genes, which specify diverse virulence functions including surface adhesins that ensure biofilm integrity. Biofilm fo

Externí odkaz: https://doaj.org/article/86426b14307945c08c01ad98f2b51576

Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality.

Autor: Katherine Lagree, Carol A Woolford, Manning Y Huang, Gemma May, C Joel McManus, Norma V Solis, Scott G Filler, Aaron P Mitchell

Publikováno v: PLoS Genetics, Vol 16, Iss 1, p e1008582 (2020)

Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way that C. albicans controls its metabolism is through the glucose repression pathway, where ex

Externí odkaz: https://doaj.org/article/afb4094d8aa24a9a8acc436b456440d7

Circuit diversification in a biofilm regulatory network.

Autor: Manning Y Huang, Carol A Woolford, Gemma May, C Joel McManus, Aaron P Mitchell

Publikováno v: PLoS Pathogens, Vol 15, Iss 5, p e1007787 (2019)

Genotype-phenotype relationships can vary extensively among members of a species. One cause of this variation is circuit diversification, the alteration of gene regulatory relationships among members of a species. Circuit diversification is thought t

Externí odkaz: https://doaj.org/article/9053167b48754a72b747454e87ce545d

Tales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages.

Autor: Karen K Klyczek, J Alfred Bonilla, Deborah Jacobs-Sera, Tamarah L Adair, Patricia Afram, Katherine G Allen, Megan L Archambault, Rahat M Aziz, Filippa G Bagnasco, Sarah L Ball, Natalie A Barrett, Robert C Benjamin, Christopher J Blasi, Katherine Borst, Mary A Braun, Haley Broomell, Conner B Brown, Zachary S Brynell, Ashley B Bue, Sydney O Burke, William Casazza, Julia A Cautela, Kevin Chen, Nitish S Chimalakonda, Dylan Chudoff, Jade A Connor, Trevor S Cross, Kyra N Curtis, Jessica A Dahlke, Bethany M Deaton, Sarah J Degroote, Danielle M DeNigris, Katherine C DeRuff, Milan Dolan, David Dunbar, Marisa S Egan, Daniel R Evans, Abby K Fahnestock, Amal Farooq, Garrett Finn, Christopher R Fratus, Bobby L Gaffney, Rebecca A Garlena, Kelly E Garrigan, Bryan C Gibbon, Michael A Goedde, Carlos A Guerrero Bustamante, Melinda Harrison, Megan C Hartwell, Emily L Heckman, Jennifer Huang, Lee E Hughes, Kathryn M Hyduchak, Aswathi E Jacob, Machika Kaku, Allen W Karstens, Margaret A Kenna, Susheel Khetarpal, Rodney A King, Amanda L Kobokovich, Hannah Kolev, Sai A Konde, Elizabeth Kriese, Morgan E Lamey, Carter N Lantz, Jonathan S Lapin, Temiloluwa O Lawson, In Young Lee, Scott M Lee, Julia Y Lee-Soety, Emily M Lehmann, Shawn C London, A Javier Lopez, Kelly C Lynch, Catherine M Mageeney, Tetyana Martynyuk, Kevin J Mathew, Travis N Mavrich, Christopher M McDaniel, Hannah McDonald, C Joel McManus, Jessica E Medrano, Francis E Mele, Jennifer E Menninger, Sierra N Miller, Josephine E Minick, Courtney T Nabua, Caroline K Napoli, Martha Nkangabwa, Elizabeth A Oates, Cassandra T Ott, Sarah K Pellerino, William J Pinamont, Ross T Pirnie, Marie C Pizzorno, Emilee J Plautz, Welkin H Pope, Katelyn M Pruett, Gabbi Rickstrew, Patrick A Rimple, Claire A Rinehart, Kayla M Robinson, Victoria A Rose, Daniel A Russell, Amelia M Schick, Julia Schlossman, Victoria M Schneider, Chloe A Sells, Jeremy W Sieker, Morgan P Silva, Marissa M Silvi, Stephanie E Simon, Amanda K Staples, Isabelle L Steed, Emily L Stowe, Noah A Stueven, Porter T Swartz, Emma A Sweet, Abigail T Sweetman, Corrina Tender, Katrina Terry, Chrystal Thomas, Daniel S Thomas, Allison R Thompson, Lorianna Vanderveen, Rohan Varma, Hannah L Vaught, Quynh D Vo, Zachary T Vonberg, Vassie C Ware, Yasmene M Warrad, Kaitlyn E Wathen, Jonathan L Weinstein, Jacqueline F Wyper, Jakob R Yankauskas, Christine Zhang, Graham F Hatfull

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0180517 (2017)

The vast bacteriophage population harbors an immense reservoir of genetic information. Almost 2000 phage genomes have been sequenced from phages infecting hosts in the phylum Actinobacteria, and analysis of these genomes reveals substantial diversity

Externí odkaz: https://doaj.org/article/65e7a5f405dc48c78507210f321a40e9

Multiplexed Analysis of Human uORF Regulatory Functions During the ISR Using PoLib-Seq

Autor: Gemma E. May, C. Joel McManus

Publikováno v: Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071619742

Protein synthesis is a highly regulated essential process. As such, it is subjected to substantial regulation in response to stress. One hallmark of the Integrated Stress Response (ISR) is the immediate shutdown of most translation through phosphoryl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffcff22fd25bf3e51a3ac3653652a3e
https://pubmed.ncbi.nlm.nih.gov/35171472