Zobrazeno 1 - 10
of 19
pro vyhledávání: '"C J Kara"'
Publikováno v:
The Journal of Immunology. 151:4173-4182
Transforming growth factor beta 1 (TGF-beta 1) is a pleiotropic cytokine that decreases the expression of class II MHC Ag in the melanoma cell line Hs294T(c). To investigate the mechanism of this repression, we have examined the effect of TGF-beta 1
Autor:
C J Kara, L H Glimcher
Publikováno v:
The Journal of Immunology. 150:4934-4942
The class II genes of the major histocompatibility complex are a family of genes whose expression is regulated developmentally in cells of the B lineage and by IFN-gamma in many other cell types. Using the approach of in vivo footprinting, which allo
Autor:
Laurie H. Glimcher, C. J. Kara
Publikováno v:
Annual Review of Immunology. 10:13-49
The expression of the class-II antigens of the major histocompatibility complex is tissue-specific, developmentally regulated in cells of the B lineage, and inducible by cytokine. Some of the molecular mechanisms that account for this regulation have
Publikováno v:
The Journal of Immunology. 146:4011-4015
The MHC class II (Ia) molecules are heterodimeric cell surface glycoproteins that have a limited tissue distribution and are essential for an Ir. These proteins are known to both display a limited tissue distribution and be responsive to up-regulatio
Autor:
Laurie H. Glimcher, C. J. Kara
Publikováno v:
Science. 252:709-712
Major histocompatibility complex (MHC) class II genes are coordinately regulated and show tissue-specific expression. With the use of in vivo footprinting, common promoter sites in these genes were found to be occupied only in cells that expressed th
Publikováno v:
Molecular and Cellular Biology. 10:1609-1621
Proto-oncogene products c-Fos and c-Jun form a complex which binds with high affinity to the 12-O-tetradecanoylphorbol-13-acetate (TPA) response DNA element and which stimulates transcription of phorbol ester- inducible genes. We have previously iden
Publikováno v:
Molecular and Cellular Biology. 10:1609-1621
Proto-oncogene products c-Fos and c-Jun form a complex which binds with high affinity to the 12-O-tetradecanoylphorbol-13-acetate (TPA) response DNA element and which stimulates transcription of phorbol ester- inducible genes. We have previously iden
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(8)
Transforming growth factor beta 1 (TGF-beta 1) is a pleiotropic cytokine that decreases the expression of class II MHC Ag in the melanoma cell line Hs294T(c). To investigate the mechanism of this repression, we have examined the effect of TGF-beta 1
Autor:
C J, Kara, L H, Glimcher
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 150(11)
The class II genes of the major histocompatibility complex are a family of genes whose expression is regulated developmentally in cells of the B lineage and by IFN-gamma in many other cell types. Using the approach of in vivo footprinting, which allo
Autor:
C. J. Kara, Laurie H. Glimcher
Publikováno v:
The EMBO journal. 12(1)
Class II-deficient combined immunodeficiency (CID) is a hereditary disease resulting in abrogation of transcription of the class II genes of the major histocompatibility complex, due to a defect in a trans-acting regulatory factor. Cell lines from ce